Journal of Clinical Care and Skills

Background: several studies have explored the relationship between blood lipid levels and depressive disorders. Specific studies reported an association between lower serum cholesterol and depressive disorder, while some other studies no connection. The aim of this study was to evaluate the relationship of serum lipid profiles and serum serotonin with depressive disorder.
Methods: In the present study, the total serum cholesterol, LDL-C, HDL-C and serum serotonin of 45 patients with depressive disorder as a case group, and 45 normal people without depressive disorder as a control group was measured. Age, sex, weight and height were matched in both groups. Diagnosis of depression was conducted by using both the Beck and Hamilton depression Rating scale, followed by an interview by a psychiatrist.
Results: The LDL-C serum concentrations of the case group was higher than the control group (121.1±30.9 vs107.9±36.9; P<0.1); moreover, the HDL-C serum of the case group was significantly lower than the control group (52.6±11.9 vs. 34.4±9; p<0.0001). The Serum serotonin of case group was higher than the control group, but this difference was not statistically significant (455.9±393 vs. 418.1±224.4).The total cholesterol and TG of case group were higher than control group, but these differences were not statistically significant (178±37.8 vs. 191.2±47 and 127.4±56.2 vs. 148.5±88.4 respectively).
Conclusions:
The Serum HDL-C concentration of depressed patients was significantly lower than the control group, suggesting a possible convers relationship between serum HDL-C and Depression. The serum LDL-C concentration of depressed patients was also higher than the controls showing a possible relationship. However there was no statistical significant difference between the total serum cholesterol, triglyceride and serum serotonin between two groups.

Background: Spiritual intelligence includes problem-solving behavior and adaptability, also spiritual intelligence helps a person to coordinate and integrate into the environment.
Objective: This study aimed to determine the relationship between spiritual intelligence and self-care in adolescents with type 1 diabetes.
Methods and materials: This was a cross-sectional study of an analytical type, 200 adolescences with type 1 diabetes in 2020 were selected using the available sampling method. It collected information from the SISRI spiritual intelligence questionnaire and Tobert's self-care questionnaire. Data were analyzed using SPSS 18 series software.
Findings: There was an inverse and indirect relationship between the total score of self-care and all subscales of spiritual intelligence (r=-0.02). There was also an inverse and indirect relationship between the total score of self-care and the age of adolescents with diabetes (r = -0.17).
Conclusion: Based on the findings of this study, we recommend that more serious and practical studies be conducted to investigate the relationship between spiritual intelligence and self-care in adolescents with type 1 diabetes.
 

Background and Aim: Improving the quality of public health depends on improving the quality of medical education. The National Committee for Quality Improvement has emphasized on creating a change in the management system and leadership of medical education in the Ministry of Health. In this regard, this study was conducted to investigate the relationship between transformational and interactive leadership styles with attitudes toward organizational change in the teaching staff of Yasuj University of Medical Sciences.
Method: This is a descriptive-correlational cross-sectional study that was conducted by census method and its statistical population includes all teaching staff of Yasuj University of Medical Sciences over 300 people who volunteered to participate in the study. Bass Multi-Factor Leadership Questionnaires were completed to assess transformational and interactive leadership and the Dunham Scale was completed to assess attitudes toward organizational change.
 Results: Among the variables included in the regression equation, the ideal influence variable is a significant predictor of the emotional dimension in the attitude to organizational change (P <0.01, β = 0.170). In the cognitive field, the variable of job satisfaction was a significant predictor for the cognitive dimension (P <0.01, β = -0.164) and also the variable of intellectual stimulation was a significant predictor for the criterion variable (P <0.01, β = -0.130).               
Conclusion: Transformational and interactive leadership, each based on certain dimensions of their existence can affect parts of the tendency to organizational change.
 

Introduction & Objective: Cough is an important problem in pediatric medicine. One of the drug regimens for the treatment of children cough are bronchodilators such as salbutamol, aminophylline, and theophylline (methyl xanthene), while the response to thromboembolism is not predictable, regardless of the underlying cause. Accordingly, since caffeine, as a central nervous system stimulant of the methylxanthine group, inhibits the alpha-Tumor necrosis factor (TNFα) and lacto-synthetase and reduces inflammation and initiates the immune process, the aim of this study was to determine the effect of caffeine on cough in 36-3 months old Children.
Materials and Methods: In this clinical trial study, 120 children aged 3 to 36 months with  the cough due to bronchiolitis, lower respiratory viral disease, elevated airway sensitivity or persistent asthma among the patients referred to the Children's Clinic of Martyr Mofattah  of Yasuj Were mild and eligible to enter the study and were randomly assigned to two groups of intervention and control. While the control group received routine treatment, the group received caffeine in combination with routine treatment. In addition to completing demographic information at the beginning of the study, information was provided the rate of daily cough and night cough at the beginning of the study, 48 hours, one week and two weeks after the start of the drug; then the collected data were analyzed by SPSS software version 21 through descriptive statistics and parametric or nonparametric statistical tests Corresponding to 95% confidence level (P = 0.05).
Result: No significant statistical difference was found between the experimental and control groups in terms of demographic and background characteristics, and the two research groups were similar at the beginning of the study (P <0.05). The rate of daily cough and night cough at 48 hours, one week and two weeks after starting treatment in the intervention group was significantly reduced in comparison with the control group (P <0.05). It is worth that in this study, nausea and vomiting as side effects of Caffeine reported in 3 cases only.
Conclusion: According to the findings of this study, it seems that the use of caffeine is effective in improving children's cough.
 

 Circumferential incision line compressive dressing in Circumcision; a comparative study between conventional dressing, no dressing and our innovative dressing
  Abstract
Background and Goal: Circumcision is a minor urologic surgery that is widely used in our country and other Muslim and non-muslin countries. Although this procedure is used as a religious duty, but there are evidence based data about its preventive role for urinary tract infections and even for genital malignancies. A common complication following this procedure is bleeding. The aim of this study was to compare our innovative dressing with no dressing and conventional dressing options for circumcision in point of bleeding after circumcision.
Patients and Methods
Between October 2010 and July 2016, 126 boys underwent elective circumcision. The patients were randomized in 3 groups. In group one conventional dressing, group 2 no dressing, and in group 3 innovative dressing was done. Patients were followed for one week and outcomes were recorded and compared.
Results:
The demographic criteria were similar in 3 groups, there were 15 reattendances for bleeding; 8 patients in group one, 7 patients in group 2 and no patients in group 3, but all had minimal bleeding and no life- threatening bleeding was encountered.
Conclusions
Circumcision is a well-known procedure with different methods of surgery, and different medical and cultural aims of performing. Bleeding is the most common complication of circumcision. In experienced hands, bleeding can be ignorable in this procedure by choosing a suitable dressing and/or good hemostasis.
Key Words: Circumcision, Bleeding, complication
 

Introduction and Objective: Asthma is a chronic inflammatory disease of the air ways, resulting in air way hyperresponiveness, mucosal edema and mucus production. According to the estimations done, near by 17 million Americans are affected by this disease and more than 500 persons die due to it's affection yearly. The present research has been carried out with the aim to assess the effect of Hypnotherapy on the improvement of symptoms of sufferers from Asthma referred to the Shahid Mofateh clinic of Yasouj city among which, 72 patients were selected as study samples. Considering the shortage of 10.0%, statistical analysis was carried out on the relative data of 64 patients. Samples were selected according to the block randomization sampling method and thereafter, each individual from case group underwent Hypnotherapy by scientific method for one session of 1.5 hours. The disease severity was studied immediately, 2 weeks and 4 weeks after intervention. Data collection were done using check list questionnaire that was completed by internist based on examination of patients and doing Peak Flow Meter before and after Hypnotherapy. Collected data were analyzed using SPSS software, descriptive statistics and inferential statistics such as X², t-test, Mann-Whitney and repeated measurement.
Results: Statistical results of Analysis of Covariance (ANCOVA) with repeated measurements indicated that, time alone had significant effect on Asthma severity (P<0.05). As a whole, changes of Asthma severity were statistically different between two case and control groups with time-lapse and without concerning time (P<0.05).
Conclusion: Totally, it seems that, Hypnotherapy as a complementary treatment in improving the symptoms of Asthma disease is effective though; the necessity of Randomized Controlled Trial (RCT) with more samples and following patients after intervention for longer period is felt.
 

Introduction & Objective: Diabetes is among the expensive diseases and in most countries. It is the primary reason for blindness, amputation and chronic renal failure. Although diabetes conditions are preventable or postponable, different studies have reported diabetes control situation as undesirable. So, this study is performed to compare the effect of face-to-face education and educational booklet on health-related quality of life in patients suffering from type 2 diabetes.
Materials & Methods: This study is clinical trial study which was performed in order to compare the effect of face-to-face education and educational booklet on health-related quality of life in patients suffering from diabetes type 2 in Jahrom city. 120 patients qualified to enter the study were selected by random sampling. They were among the patients visiting the selected clinics; they were randomly allocated to three groups: education through educational booklet, face-to-face group, and control group. In order to gather the data, personal and social information form, standardized health-related quality of life questionnaire in diabetic patients were used. Questionnaires about complying the health-related quality of life were completed before and two weeks after the intervention. Gathered data was analyzed by SPSS software. Due to the aims of the study, absolute and relative frequency distribution were used; moreover, in order to investigate the relation between the variables depending on distribution of consequence variables, parametrical and non-parametrical tests were used in a 95 percent confidence interval.
Findings: Intergroup comparison of the average results of health-related quality of life in the face-to-face, booklet and control groups, before and after the intervention, reveals that average results for quality of life in three groups had no significant difference before the intervention (P=0.1). However, after the intervention, average results for quality of life in face-to-face (59.37±5.6) and booklet group (57.47±9.26) were more were more than the control group (48.8±9.6) and there was a significant difference (P=0.001).
Conclusion: Although face-to-face and booklet education have the same effect on quality of life, both interventions could improve dimensions quality of life in comparison with control group.
 

Aim: Determine the effect of early ambulation in bed on hemodynamic parameters and complication of sleeve gastrectomy.
Materials and Methods: In this randomized clinical trial, 88 volunteer patients were selected by available sampling method. Hemodynamic parameters were recorded for all patients at the time of entry to the department immediately, six hours, twelve hours and twenty four hours after leaving the bed. 
 Results: The changes in systolic blood pressure and diastolic blood pressure in the intervention group at each time interval after the intervention were significantly different in the control group compared with those in the control group. Also, changes in arterial oxygen saturation in the intervention group, at each time interval after the intervention  were statistically significant in comparison with these changes in the control group.
Conclusion: The effect of early out of the bed compared to the conventional procedure for the removal of the patient from the bed following the sleeping gastrectomy surgery is in the balance of systolic blood pressure, diastolic blood pressure and arterial oxygen saturation .
 

Parigol Taheri*, Kheirollah Nooryan*^*, Mohammad Zoladl*, Zohreh Karimi*
^* Yasuj University of Medical Sciences,Yasuj, Iran
^**Corresponding author: Kheirollah Nooryan, Email: khnooryan@gmail.com

Abstract
Background & Objective: Thalassemia is a one of the most common inherited chronic diseases in the world. Hereditary disease, which emerged in the first years of life, the risk of physical abnormalities and ongoing need for blood transfusion and chelation have significant impact on the growth and evolution of patients with thalassemia and their relationship with other members of the family. So, the study aim was determine the effect of individual psychotherapy with a focus on self-efficacy on quality of life in patients with thalassemia major.
Materials & Methods: In this clinical trial study sample was 50 patients with thalassemia major referred to Shahid Rajai Hospital in Gachsaran (Southern Iran) that has eligible and defined criteria for research units. Using block random allocation 25 of them in the intervention group and 25 of them was assigned to the control group. Data were collected in this study using a three-part questionnaire consist of demographic questionnaire, Quality of Life Questionnaire (SF-36) and Scherer Self-efficacy Questionnaire was completed by the subjects.  Data were analyzed using SPSS software version 21, by descriptive and inferential test, considering the 95% statistical confidence interval.
Results: The findings showed that the mean age of 21±6.27 years and rank of their children in the family was 3.24±1.94, the highest level of high school education, majority of singles, highest mean employment for people who are studying, more patients in the city and more patients have changed in appearance. The mean score of self-efficacy in two groups were significantly different (P<0.05). There were no significant different between mean scores of physical dimension for quality of life in the two groups, but the mental aspect of quality of life were significantly different (P<0.05).  
Conclusion: According to the results, it seems to increase the self-efficacy and following quality of life in patients, measures such as training workshops for patients, the presence of psychologists in the field of blood transfusion and facilitating therapy can be effective.
 

Background and objective: From past times, herbal medicine had wide usage in Iranian conventional medicine, and nowadays, Alhagi pseudoalhagi (that is the gum of Alhagi plant) and purgative manna are still used for treatment of icterus in infants. The aim of this study was to assess the effect of purgative manna, Alhagi pseudoalhagi, and their simultaneous use on healing icterus of infants hospitalized in Imam Sadjad hospital of Yasuj in 2016.
Materials and Methods: In this interventional study with clinical trial, the groups were divided into three groups including two intervention groups (Alhagi pseudoalhagi extract group, purgative manna extract group) and one control group, and grouping performed by random block allocation. 30 infants placed in each group that needed treatment. At the end, age, gender, blood group, total and direct bilirubin, and G6PD were evaluated in the patients. Data were statistically analyzed using SPSS software version 21, and using One-way ANOVA and Tukey's follow-up test. P<0.05 was considered to be statistically significant.
Results: Results of this study showed that the phototherapy group had higher total and direct bilirubin mean in comparison to the Alhagi pseudoalhagigroup. Based on our results, Alhagi pseudoalhagi had more effectively decreased bilirubin level in comparison to the phototherapy and purgative manna groups. Phototherapy and,purgative manna groups had similar results. No significant difference was seen regarding serum bilirubin reduction between two phototherapy (control) and,purgative manna groups, and in spite of conventional ideas had no effect on reduction of icterus in hospitalized infants.
Conclusion: Regarding our results and assessment of the effect of oral Alhagi pseudoalhagiand purgative manna on reduction of icterus in infants in different studies, using oral Alhagi pseudoalhagi(5 drops for 3 times per day and for 3 days) is recommended for helping treatment of icterus in infants.

Introduction & Objective: Cancer is an important chronic non communicable disease. Chemotherapy as one of main treatment of cancer had side effects, especially fatigue as one of prevalent side effects of chemotherapy. Accordingly and because despite the confirmation of the positive effect of psychological and self-management based interventions on the relief of side effects of chronic diseases, so this study carried out to determine the effect of intervention relying 5 A’s program of self-management on fatigue severity of cancer patients under chemotherapy.
 Material & Methods: In this randomized clinical trial, 60 cancer patients under chemotherapy who referred to Chemotherapy Center of Shahid Motahari Clinic of Shiraz University of Medical Sciences, and were eligible based on inclusion criteria,  selected using convenience sampling, then using block random allocation divided to experimental and control group with the equal number. While control group received routine treatment and care related to chemotherapy, 5 A’s program of self-management including assessment, advisement, agreement, assistance and arrangement in the four sessions (two individual sessions, two group sessions),during four months was applied for experimental group based on protocol in addition to routine treatment and care related to chemotherapy. The data gathering tool of current study consists of a demographic questionnaire and Multidimensional fatigue inventory (MFI) completed by all subjects at the beginning of the study, end of the intervention, and 3 months later. The data analyzed by the descriptive statistic such as mean and standard deviation, and analysis of variance with repeated measurement as an inferential statistic using SPSS 21 software.
Result: Immediately after research intervention, the fatigue severity amount in the intervention group(43.4±7)was less than this amount in the control group(46.8±13); but 3 months after research intervention, the fatigue severity amount in the control group(34.7±10.1) was more less than this amount in the intervention group(42±4.8); which these differences were statistical significance. In the intervention group, there were 11.4 and 12.8 significant decrease between the fatigue severity of immediately and three months after the end of the intervention compared to the starting point of the study accordingly(P<0.05); but there were no significant differences regarding 1.5 decreases between the fatigue severity of the follow up compared to post-test (P>0.05). In the control group, there were no significant differences regarding 2.2 decreases between the fatigue severity of the end of the intervention compared to the starting point of the study (P>0.05); but there were 14.3 and 12.1 significant decreases between the fatigue severity of  the three months after the end of the intervention compared to the starting point of the study and immediately after the end of the intervention accordingly (P<0.05).
Conclusion: The  finding showed that the 5 A’s program of self-management produce a decrease  in fatigue severity of cancer patients under chemotherapy who were in the intervention group: but this independent variable couldn't perform significant differences between the intervention group and  control group regarding fatigue severity that confirmed the effectiveness of mentioned intervention; so wider researches with more accurate and more sensitive design  recommended.

Aims: Preterm labor (delivery earlier than 37 weeks) is one of the most common problems with
midwifery. Recently, vitamin D deficiencies have been reported with adverse maternal outcomes
such as pregnancy toxicity, intrauterine growth limitation, and preterm labor. The aim of this study
was to compare the effect of two vitamin D doses (VIt D-Ca and VIt D-Ca+VIt D) from the 16th week
on preterm labor in pregnant women.
Materials and Methods: In this single-blind randomized clinical trial, from January 2015 to April
2016, 202 pregnant women from 5 gynecological and obstetric clinics in Bandar Abbas, Hormozgan
province were selected by …. sampling method; they were randomly divided into experimental
(150 people) and control (152 people) groups. The experimental group (A) received the VIt D-Ca
supplement containing IU/day400 and the control group (B) received the VIt D-Ca supplement plus
Vit D for IU/day1000 from the 16th week of pregnancy until delivery. Research subjects were
examined from the 16th week of pregnancy to delivery. Data analysis was performed, using SPSS 21
software by T ... (type?) test, Mann-Whitney Yu, and Chi-square.
Finding: There was a significant difference between groups A and B in terms of preterm labor. The
incidence of preterm delivery was lower in the VIt D-Ca+VIt D group than in the VIt D-Ca group
alone (p=0.01).
Conclusion: The consumption of Vit D-Ca and vitamin D reduces preterm delivery in pregnant
women more than in Vit D-Ca alone.
 

Aims: Cancer disrupts the quality of life of patients, as well as increases the care burden of the patients' families. The current study aimed to determine the effect of Glenn Abdellah's nursing theory on quality of life of patients with cancer.
Materials & Methods: In this randomized control trial, 60 patients with cancer were selected by purposive sampling method in Shahid Modarres Hospital, Saveh city in 2020.
Then the samples were divided into intervention and control groups using random allocation. Then the samples were divided into intervention (n=30) and control (n=30) groups using random allocation. The intervention related to ten steps in Faye Glenn Abdellah’s Nursing Theory was implemented for intervention group, but there was no intervention in the control group. Information was collected before, after the intervention, and one month after the intervention through World Health Organization Quality-of-Life Scale (WHOQOL-BREF). Data were analyzed by SPSS 22 software, using descriptive statistics methods and inferential analysis tests.
Findings: In the intervention group, the mean score of patients' quality of life increased significantly after intervention and one month after intervention (p<0.001). After intervention and the follow-up period, the quality of life in the intervention group was better than that of the control group (p<0.001).
Conclusion: The use of nursing care theories, such as Faye Glenn Abdellah's nursing theory, can improve the quality of life in cancer patients.

 

Abstract
Aim: Asthma is one of the common, chronic respiratory diseases which psychological factors play an important role in it and comorbidities of several psychological disorders such as anxiety, depression, and panic attacks are common in asthmatic patients. The aim of this study was to determine the effect of hypnosis on pulmonary function and severity of the disease in asthmatic patients.
Materials and Methods: This randomized clinical trial study, was carried out on 64 asthmatic patients, who referred to the clinic of Shahid Mofattah in Yasuj, Iran in 2010. The subjects were selected by purposeful sampling method, and randomly assigned into the tow group of the intervention (subjects were treated by solo hypnosis in a 90-minute session and conventional treatments) and control group (subjects were treated by conventional treatments, in addition, providing an explanation about requirement care point for improvement of asthma in 15 minutes) by use of balanced block randomization. In addition to completing demographic information at the beginning of the study, determination of pulmonary function and asthma severity were conducted respectively through measurement of FEV1 and NAEPP classification (EPR-3) at the starting point of the study and one month after the completion of the research intervention. Data were analyzed using SPSS 21 software, through independent sample t-test, paired sample t-test, Chi-square test, and marginal homogeneity test.
Findings: one month after completing the research intervention, the FEV1 in the intervention group increased than the control group and the severity of asthma in the intervention group decreased than the control group.
Conclusion: Hypnosis as an adjuvant treatment is effective in the improvement of pulmonary function and reducing the disease severity in asthmatic patients.

Aims: Coughing is one of the most common clinical complaints in pediatric medicine. Since caffeine, as a central nervous system stimulant from methylxanthine, inhibits tumor necrosis factor-alpha (TNFα) and leukotriene synthesis and reduces inflammation and initiates the immune process, the aim of this study was to determine the effect of caffeine on coughing in children aged 3-36 months.
Materials and Methods: In this randomized clinical trial study in 2015, among children referred to the Shahid Mofateh Pediatric Clinic of Yasuj, 120 children aged 3-36 months with coughing due to bronchiolitis, lower respiratory viral disease, increased airway sensitivity, or moderate persistent asthma were selected by convenience sampling method. They were assigned in intervention (reciving salbutamol and caffeine) and control (reciving salbutamol alone) groups by quadratic block randomization. In addition to completing demographic information at the beginning of the study, data on daily and nocturnal cough at the beginning of the study, 48 hours, 1 week, and 2 weeks after starting the drug were recorded. The data were analyzed by SPSS 21 software, using Mann-Whitney test, Chi-square or Fisher's exact test, generalized estimating equation, Friedman, and Wilcoxon statistical tests.
Findings: Daily cough and nocturnal cough significantly decreased in the intervention group at 48 hours, 1 and 2 weeks after beginning the treatment (p<0.05).
Conclusion: Prescription of caffeine with salbutamol is effective in accelerating improvement of cough in children.
 

Aim(s): Obesity in pregnant women is a serious health problem that has many complications such as pre-eclampsia and fetal growth restriction (FGR). The aim of the present study was to evaluate the effect of aspirin on prevalence of pre-eclampsia and FGR in obese pregnant women.
Materials & Methods: This randomized controlled clinical trial was conducted on 187 pregnant women referring to birth center of Mofatteh Clinic, Yasuj University of Medical Sciences, Yasuj, Iran in 2017-2018.
The subjects were selected using purposive sampling method and randomly divided into two groups; intervention group (n=89) and control group (n=98). The intervention group received 80mg/day aspirin and the control group received placebo at 13-20 weeks of gestation until 34 weeks of pregnancy. Data were analyzed by SPSS 21 software using Chi square test.
Findings: The prevalence of pre-eclampsia (1.1 vs. 11.2) and FGR (3.4 vs. 21.4) were significantly lower in the intervention group compared to the control group (p<0.05).
Conclusion: Administration of 80mg/daily of aspirin from 13-20 weeks of gestation in obese pregnant women reduces the incidence of pre-eclampsia and FGR, which could support the positive role of aspirin in preventing pre-eclampsia and FGR.

Aims: Hospital indicators are one of the most important criteria of hospital efficiency. The aim of this study was to determine the performance indicators of affiliated hospitals of Yasuj University of Medical Sciences in 2011-2018.
Instruments & Methods: This cross-sectional descriptive study was conducted on 5 hospitals, including Shahid Beheshti, Shahid Rajaei, and Emam-Sajjad Yasuj hospitals, and Shahid Rajaei Hospital in Gachsaran and Emam-Khomeini Hospital in Dehdasht affiliated to Yasuj University of Medical Sciences in 2011-2018. Bed Occupancy Rate (BOR), Bed Turnover (BTR) and Average Length of Stay (ALS) were collected through hospital information system and analyzed according to Pabon Lasso model and compared with the standard levels.
Findings: The mean BTR (98.76 times per year), ALS (2.12 days) and BOR (70.9%) in hospitals in 2011-2018 were favorable. ALS was 15.24 days in Shahid Rajaei hospital in Yasuj. Shahid Beheshti hospital was in zone 3 in all years. Emam-Sajjad hospital was in zone 3 in all years except 2014. Shahid Rajaei hospital of Yasuj was in zone 4 in 2011-2018. Emam-Khomeini hospital was in zone 1 in 2015-2016, zone 3 in 2011-2012, 2014, 2017-2018, and zone 4 in 2013. Shahid Rajaei hospital of Gachsaran was in zone 3 only in 2012, zone 1 in 2016-2019 and zone 2 in 2011 and 2013-2015.
Conclusion: The performance indicators of affiliated hospitals of Yasuj University of Medical Sciences are at the favorable and moderate level, and in total, in 2011-2018, most of the hospitals have been in zone 3, which indicates good performance.
 

Aims: Interleukin-10 is an important immunoregulatory cytokine that has an inhibitory effect on the initiation and progression of inflammatory responses in different situations such as autoimmune diseases including rheumatoid arthritis. Polymorphism in IL-10 promoter region affects the expression of this gene. It therefore seems reasonable that these polymorphisms may contribute to rheumatoid arthritis susceptibility in special populations. the aim of this study was to investigate the association between IL-10 rs1800872 polymorphism in the promoter region of human IL-10 gene and susceptibility to rheumatoid arthritis in the patients in southwest of Iran.
Materials & Methods: The present study is a case-control study conducted among patients with and without rheumatoid arthritis referred to the Mofateh clinic in Yasuj, Iran. Both case (n=64) and control (n=65) groups were selected using purposive sampling and were matched in terms of age, gender and ethnicity. Peripheral blood samples were collected from subjects and rs1800872 genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism method. SPSS 26.0 software was used for statistical analysis of data
Findings: The association between the frequency of TT genotypes and the incidence of rheumatoid arthritis was significant (OR=6.45; 95% CI= 1.30-32.00; p=0.023). On the other hand, the distribution of the T allele showed a significant relationship with rheumatoid arthritis (OR= 2.23; 95% CI= 1.26–3.97; p=0.006).
Conclusion: TT genotype of rs1800872 polymorphism is associated with rheumatoid arthritis susceptibility in southwestern Iranian population and can be considered as a risk factor for rheumatism.
 

Aims: Psoriasis is a common immune-related skin disorder that affects 2-3% of worldwide people. This study aimed to determine the disease characteristics of psoriasis patients.
Materials & Methods: In this descriptive cross-sectional study, using the convenience sampling method, 164 psoriatic patients who were referred to a dermatology clinic in Yasuj from 2013 to 2014 participated. Demographic information and medical parameters were collected by a dermatologist through observation and using a researcher-made checklist. SPSS software version 19 was used for the statistical analysis of data.
Findings: Participants were consisting of 106 males and 58 females. The mean age of females was 28.72±15.89, and for males was 29.83±23.19. Most of them had the mild disease (48.3%), and common plaque-type psoriasis (87.7%). Sites of skin involvement were 80.4% on extremities. Nail involvement was 31.7% and arthritis was detected in 3% of cases. There was a history of pruritus or burning sensation in 41.5% of cases. There was only a 17.1% positive family history.
Conclusion: According to the results of this study, the ratio of men with psoriasis to women was higher. Most of the skin lesions caused by this disease were observed in the extremities, head, face and trunk, respectively, and in this respect both gender were similar and few participants reported a positive family history in this regard.

Aims: Chronic non-specific low back pain is the most common chronic lower back pain, and developing a therapeutic and rehabilitative plan to more rapidly mend patients with lower back pain has always been discussed. The present study aimed to determine the effect of prayer-based movements on pain and endurance of flexor muscles in patients with non-specific chronic low back pain.
Materials & Methods: This quasi-experimental study was conducted on all the patients with a chronic non-specific LBP referring to Shahid Mofatteh Clinic No. 1 in Yasuj, 2020. According to block random assignment, Sixty-six patients were divided into two groups of the intervention and control. In the intervention group, prayer-based exercises were performed three sessions a week for eight weeks. The control group was not instructed. The demographic questionnaire and Quebec back pain disability scale were used to measure pain, and the maintain the 60° angle test was used to collect data before intervention; the visual pain measurement scale was used immediately after the intervention, and the endurance test of spine flexor muscles performed at the angle of 60° was used a week after the intervention. The collected data were analyzed by SPSS 21 using descriptive statistics and statistical tests of Paired T, Mann-Whitney, Independent T, Wilcoxon, Chi-square, and Shapiro-Wilk.
Findings: There was no significant difference between the two groups in terms of pain severity and endurance of the flexor muscles at the starting point (p>0.05). The comparisons of the mean immediately and a week after the intervention were significant (p<0.05).
Conclusion: Prayer-based exercises effectively affect pain severity and endurance of flexor muscles in patients with non-chronic lower back pain.

Aims: Mothers whose children suffer from chronic diseases experience high levels of stress. Promoting the sense of coherence can be a way to reduce the stress. The aim of this study was to compare the effect of teach-back method and video clip teaching on the sense of coherence of mothers with children suffering from asthma.
Materials & Methods: In this randomized controlled trial, 75 eligible mothers with children suffering from asthma in Yasuj in 2020 were selected by convenience sampling method and randomly assigned into three groups: video clip group, teach-back method group and control group. In video clip group, training was performed through a 15-minute clip in two sessions. In teach-back method group 8 training sessions were held. Data were collected using the Antonovsky's Sense of Coherence scale-13 at baseline and one month after the intervention. Data were analyzed using SPSS 21 by descriptive and inferential statistics.
Findings: Before the intervention, there was no significant difference in the mean score of sense of coherence and its subscale in the three groups (p>0.05). One month after the intervention, there was a significant difference in the mean score of sense of coherence and its subscales between the two intervention groups with the control group (p=0.001). Also, a significant difference was observed between the two intervention groups in the mean scores of the sense of coherence and comprehensibility (p<0.05).
Conclusion: Both video clip and teach-back methods improves mothers' sense of coherence, but teach-back method is more effective than video clip teaching.

 

Aims: The aim of this study was to investigate the effect of individual psychotherapy with a focus on self-efficacy on quality of life in patients with thalassemia major.
Materials and Methods: In this randomized clinical trial study in 2016, among patients with thalassemia major referring to Cooley's anemia ward of Shahid Rajaie Hospital in Gachsaran, Iran, 50 eligible patients were selected by convenience sampling method. They were assigned in intervention (n=25) and control (n=25) groups by quadratic block randomization. Each of 50 subjects signed the informed written consent. Demographic questionnaire and 36-Item Short-Form Health Survey (SF-36) were used as the research tool. The data were analyzed by SPSS 21 software, using Chi-square test, independent T-test, and the Mann-Whitney U test.
Findings: One month after the intervention, the scores of the Physical Component Summary (2461.8±15.7) and the Mental Component Summary (1873.0± 21.6) in the intervention group were significantly higher than the same scores (2283.2±279.8) and (1712.6±270.5) in the control group (p<0.05). At this time, the score of all Health Domain Scales of SF-36 Health Survey in the intervention group were higher than the same scores in the control group. These differences were significant except for the Role-Physical and Bodily Pain (p<0.05). 
Conclusion: Individual psychotherapy with a focus on self-efficacy is effective on increasing quality of life of patients with thalassemia major.

Introduction: Fibroepithelial stromal polyp (FESP) of the female lower genital tract is a rare benign lesion characterized by polypoid proliferation of stroma, covered by a benign squamous epithelium in the vulvovaginal region. These hormone-sensitive lesions usually occur in young to middle-aged women. The lesions are typically no larger than 5 cm in diameter and are found randomly during routine gynecologic examinations.
Patient Information: The case of this study was an 88-year-old man with a solitary polypoid lesion measuring 3×2×2 in the low back area showing the histological appearances of those described in the vulvovaginal region.
It was a well-circumscribed gray-brown lesion covered by wrinkled skin. Histopathological examination revealed edematous hypocellular lesion at low magnification with hyperplastic squamous epithelium coating with reactive epithelial change. At high magnification, the lesion consisted of bland-appearing spindle and stellate-shaped cells in an edematous and fibrous stroma with a large number of variably-sized blood vessels. Immunohistochemistry showed the lesional cells to be focally immunoreactive for EMA and negative for CD34, SMA in stromal cells.
Conclusion: FESPs is an uncommon benign lesion that can occur in men and areas other than the genitals with independence from female sex hormones. Although this is a benign finding, reporting it will increase the knowledge about this rare tumor.

 

Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.
Materials & Methods: In this clinical trial, 90 patients with lumbosacral radiculopathy referring to the clinic of Shahid Mofatteh, Yasuj, Iran in 2018, were selected using purposeful convenience sampling and divided into intervention (N=45) and control (N=45) groups. The pain severity was assessed by a standard visual analog scale (VAS). In the intervention group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin, and in the control group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin placebo were prescribed. After 8 weeks, the severity of the pain was again assessed and compared.
Findings: At the beginning of the study, the mean pain severity in the intervention and control group did not differ significantly (p>0.05). After the intervention, the mean pain severity between the two groups did not show a significant difference (p>0.05). The severity of the pain did not differ significantly between the two groups of intervention and control according to age, disease history, location of pain, and body weight (p>0.05).
Conclusion: The efficacy of pregabalin and NSAID in comparison with NSAID use in patients with lumbosacral radiculopathy is not different in reducing pain severity.Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.
 

Aims: This study aimed to examine the acute effects of exhaustive incremental exercise on serum leptin, glucose, and lactate in one session in trained 18-26 years old men.
Material & Methods: The present study was conducted in 2021 on male physical education students available at the Faculty of Sports Sciences of the Shahid Chamran University of Ahvaz in Iran. Thirty students who had 18-26 years old, with body fat between 15-25% and VO2max between 35-45ml/kg/min, were simple randomly selected through 200 physical education students, and they were divided into two equal training and the control groups (each of them consists of 15 subjects). The exercise test included the Astrand test on a treadmill that performed exhaustive incremental exercise. Blood samples have been collected from two groups in pre and post-test and 9 hours after exhaustive incremental exercise. The statistical analyses used were the Independent T-test and one-way ANOVA tests by SPSS version 20.
Findings: Results showed that serum leptin did not change between three measurement sets in the training group in comparison to the control group (p>0.05). Plasma glucose significantly changed between pre and post-test and pretest and 9 hours later (p<0.001). Plasma lactate significantly changed in post-test in comparison to pretest and 9 hours later to post-test (p<0.001).
Conclusion: Incremental exhaustive exercise has no significant effect on serum leptin.
 

There is no abstract.
 

Aims: Currently, the outbreak of COVID-19 has imposed a wide range of stressors that can negatively affect nurses and other health care workers. This study aimed to investigate the severity of burnout among nurses working in COVID-19 wards.
Instrument & Methods: This cross-sectional descriptive study was conducted in 2019 on 372 nurses working in the clinical wards of Shahid Beheshti Hospital of Kashan, Iran. A two-part questionnaire was used for data collection. The first part consisted of demographic questions and the second part was the Maslach burnout inventory. Data analysis was conducted by the SPSS 16 using Mann-Whitney U and independent samples t-test.
Findings: Of 372 nurses who participated in this study the mean overall occupational burnout was 45.16±22.84 which shows burnout at a moderate level. The mean occupational burnout was significantly higher in nurses over the age of 30 (p< 0.01), in males (p=0.05), and nurses working in operating rooms (p<0.001).
Conclusion: The level of nurses' burnout was moderate.