en پژوهشی اصيل Original Research <strong>Aims<em>:</em></strong> With the announcement of the coronavirus pandemic by the World Health Organization, many people experienced many waves of panic. The disease was a major threat to individuals&#39; physical and mental health because of the rapid spread and severe mortality. The continued development and changes in the educational process can affect student&#39;s mental health. This study aimed to investigate the frequency of posttraumatic stress disorder, anxiety, depression, and stress in students of Rafsanjan University of Medical Sciences during the coronavirus outbreak in 2020.<br> <strong>Materials & Methods:</strong> This cross-sectional descriptive study was conducted on students of Rafsanjan University of Medical Sciences. The sample size was 351 individuals selected by the convenience sampling method. Data were collected by DASS-21 and IES-R. Data were analyzed by SPSS18 using the chi-squared and Fisher&#39;s exact tests.<br> <strong>Findings:</strong> The majority of students had moderate anxiety (33.6%) and posttraumatic stress disorder (26.2%). Depression (38.5%) and stress (55.3%) were not common in most students. Analysis of logistic regression showed a significant correlation between anxiety, stress, depression, and Posttraumatic stress disorder (p<0.05).<br> <strong>Conclusion:</strong> The results suggest mental health problems among medical students. Therefore, it is recommended to implement psychological counseling programs to reduce these cases. COVID-19,Students,Anxiety,Depression,Stress,Posttraumatic stress disorder, 87 93 http://jccs.yums.ac.ir/browse.php?a_code=A-10-128-1&slc_lang=en&sid=1 A. Najjar Mohiabadi 10031947532846005595 10031947532846005595 No Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran M. Tajadini maryam.tajadiny@gmail.com 10031947532846005596 10031947532846005596 Yes Department of Anesthesiology, Faculty of Para‐ medical, Rafsanjan University of Medical Sci‐ ences, Rafsanjan, Iran S.H. Seyedbagheri 10031947532846005597 10031947532846005597 No “Non-Communicable Diseases Research Center” and “Department of Pediatric Nursing, Nursing and Midwifery School”, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Y. Soltanmoradi 10031947532846005598 10031947532846005598 No Department of Operating Room, Faculty of Paramedical, Rafsanjan University of Medical Sciences, Rafsanjan, Iran A.R. Sayadi 10031947532846005599 10031947532846005599 No “Department of Psychiatric Nursing, School of Nursing and Midwifery” and “Social Deter‐ minants of Health Research Center”, Rafsanjan University of Medical Sciences, Rafsanjan, Iran F. Harandi 10031947532846005600 10031947532846005600 No Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran M. Jamali 10031947532846005601 10031947532846005601 No Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran M.H. Kamrani 10031947532846005602 10031947532846005602 No Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran H. Khodadadi 10031947532846005603 10031947532846005603 No “Non-Communicable Diseases Research Cen‐ ter” and “Department of Health in Disasters and Emergencies, School of Health”, Rafsanjan Uni‐ versity of Medical Sciences, Rafsanjan, Iran