en توصيفی و نظرسنجی Descriptive Study <span style="font-size:10pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span cambria="" lang="EN-GB" style="font-family:">Aims:</span></b><span cambria="" lang="EN-GB" style="font-family:"> The COVID-19 pandemic has been a global crisis for more than two years, which caused an immense global burden on economy, health care and education. More than 250 million people have been infected with this novel virus, among which more than 5 million have died. Prevention is the best strategy against COVID-19 infection in both children and adults. This narrative review aimed at summarizing the important epidemiological and clinical findings of COVID-19 infection and its transmission, clinical manifestation, laboratory findings, radiographic findings, and diagnosis.</span></span></span></span><br> <span style="font-size:10pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span cambria="" lang="EN-GB" style="font-family:">Conclusion:</span></b><span cambria="" lang="EN-GB" style="font-family:"> Reports have shown that paediatric patients are often exposed to the SARS-CoV-2 virus through a family member, and that COVID-19 infection is a serious threat to this vulnerable age group. Milder or asymptomatic manifestations of this new disease in younger patients should not cause this population to be neglected.</span> <span cambria="" lang="EN-GB" style="font-family:">Numerous epidemiological and clinical studies have reported the burden of this novel infection in children and the chance of severe forms of infection, hospitalisation, and admission to ICU. However, many aspects of pathophysiological and immunological mechanisms regarding COVID-19 infection in children are still unexplained. Clinical characteristics of COVID-19 infection is different in children compared to adults, and a comprehensive knowledge regarding this distinction can lead to timely diagnosis and successful management of COVID-19 in these patients.</span> <span lang="EN-GB" style="font-family:"Cambria","serif""></span></span></span></span><br> <span style="font-size:10pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-family:"Cambria","serif""></span></span></span></span><br> &nbsp; COVID-19,SARS-COV-2,Pediatrics,Patients,Diagnosis,Clinical Manifestation,Transmission, 119 124 http://jccs.yums.ac.ir/browse.php?a_code=A-10-179-1&slc_lang=en&sid=1 M. Shahamat mahmoudshahamat01@gmail.com 10031947532846005711 10031947532846005711 Yes Department of Pediatrics, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran