en Infection Control Infection Control پژوهشی اصيل Original Research <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Aims:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> Every year around the world, hospital infections and resistance to antibiotics lead to many complications in hospitalized patients. This study aimed to determine and compare the antibacterial effect of hydroalcoholic extract of <i>Rosa canina</i> plant (<i>Rosa canina L</i>) on Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus bacteria isolated from surgical wounds in Yasuj hospitals.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Materials & Methods:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> In this cross-sectional study, the effect of <i>Rosa canina L</i> hydroalcoholic extract on 20 samples of Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus was investigated. The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and zone of inhibition (ZOI) of each clinical sample were investigated and compared with the standard sample. The results were statistically analyzed by SPSS 16 software.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Findings:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> <i>Rosa canina L</i> hydroalcoholic extract had no antibacterial effect on Pseudomonas aeruginosa. The lowest inhibitory concentration was related to Staphylococcus aureus 125 &micro;g/ml, Escherichia coli 325 &micro;g/ml and Klebsiella pneumoniae 350 &micro;g/ml, respectively. The difference in minimum MIC, MBC and ZOI between clinical and standard samples was not statistically significant. The ZOI diameter of Klebsiella pneumoniae and Escherichia coli clinical samples were equal (9.8 mm).</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Conclusion:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> The hydroalcoholic extract of <i>Rosa canina L</i> has a better antimicrobial effect on Staphylococcus aureus than the other 3 investigated bacteria and has no effect on Pseudomonas aeruginosa. There is no difference between the effect of the examined extract on clinical and standard samples, and the effect of this extract on different bacteria is different.</span></span></span></span></span><br> &nbsp; Plant Extracts,Rosa,Anti-Bacterial Agents,Bacteria, 157 163 http://jccs.yums.ac.ir/browse.php?a_code=A-10-108-4&slc_lang=en&sid=1 E. Masnavi 10031947532846003945 10031947532846003945 No Department of Obstetrics and Gynecology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran S. Hassanzadeh 10031947532846003946 10031947532846003946 Yes Department of Internal Medicine, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran K. Karimi 10031947532846003947 10031947532846003947 No Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran J. Malekzadeh 10031947532846003948 10031947532846003948 No Department of Nutrition Sciences, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran S.S. Khoramrooz 10031947532846003949 10031947532846003949 No Department of Microbiology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran