en Mental Health Mental Health توصيفی و نظرسنجی Descriptive Study <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Aims:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> The current study aimed to investigate the relationship between metacognitive beliefs and perfectionism concerning rumination among individuals with multiple sclerosis. This research sought to understand how these psychological factors contribute to the exacerbation of symptoms in multiple sclerosis patients.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Instrument & Methods</span></span></span></b><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> This correlational study involved a sample of 160 patients with multiple sclerosis from the Multiple Sclerosis Association of Yazd in 2024. Participants completed psychological assessments using the Frost Multidimensional Perfectionism Scale, the Metacognitions Questionnaire, and the Ruminative Response Scale. Statistical analysis was conducted using descriptive statistics and inferential statistics (regression analysis) with SPSS 29 software.<b><span style="color:#44546a"></span></b></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Findings:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> There was a significant positive correlation between metacognitive beliefs, perfectionism, and rumination in patients with multiple sclerosis (p<0.001). Hierarchical regression analysis and correlation tests showed that rumination could be predicted by both metacognitive beliefs and perfectionism in this population.<b><span style="color:#44546a"></span></b></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#44546a">Conclusion:</span></span></span></b><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> There was a significant association between metacognitive beliefs and perfectionism with rumination in MS patients.<b><span style="color:#44546a"></span></b></span></span></span></span></span><br> &nbsp; Metacognition,Perfectionism,Rumination Cognitive,Multiple Sclerosis, 33 38 http://jccs.yums.ac.ir/browse.php?a_code=A-10-336-1&slc_lang=en&sid=1 A.M. Mirbagheri 10031947532846005365 10031947532846005365 No Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran A. Hamoun 10031947532846005366 10031947532846005366 No Department of Clinical Psychology, Islamic Azad University, Yazd Branch, Yazd, Iran Z. Hazareh 10031947532846005367 10031947532846005367 No Department of Psychiatry, School of Medicine, Shahid Sadougi University of Medical Sciences, Yazd, Iran M. Hazareh 10031947532846005368 10031947532846005368 No Department of Psychiatry, School of Medicine, Shahid Sadougi University of Medical Sciences, Yazd, Iran R. Bidaki 10031947532846005369 10031947532846005369 Yes Department of Psychiatry, Fellowship of Neuropsychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran