Journal of Clinical Care and Skills

en Health Related Quality of Life, Perceived Stress, Depression, Perceived Social Support, Coping Strategies and Health Locus of Control in Patients with Gastrointestinal Cancer; A Path Analysis Study Nursing Management Nursing Management پژوهشی اصيل Original Research <div style="text-align: justify;">Aims Gastrointestinal (GI) cancer is commonly increasingly prevalent among Indians and improvement of health related quality of life (HRQOL) has been one of goals in health care for people living with cancer. The aim of this study was to examine the relationships between perceived Stress, depression, perceived social support, coping strategies and Health locus of control (HLOC) with health related quality of life (HRQOL) in patient with gastrointestinal cancer. Materials & Methods In this cross sectional study 100 Indian patients with GI cancer were selected with convenience sampling method from Nizam’s Institute of Medical Sciences (NIMS) Hospital in Hyderabad, India from July 2013 to September 2014. Data were collected using questionnaires. Relationships between variables were tested by path analysis, using SPSS/AMOS 23. Findings Maladaptive coping directly and negatively correlated with HRQOL (β=−0.15), mediated by perceived stress. HRQOL of the patients with cancer, who used more maladaptive coping perceived more stress, was worse. Perceived Social Support directly and positively correlated with HRQOL (β=0.44) mediated by perceived stress and depression, demonstrating that patients with higher perceived social support experienced less stress and depression; therefore, they have better HRQOL. Depression (β=−0.40) and Perceived Stress (β=−0.22) directly and negatively correlated with HRQOL. Perceived stress was mediated by Depression. There was no significant association between HLOC and HRQOL. Conclusion The important role of social support needs to be communicated to family members in home visits. Promoting Coping and Adjustment to cancer and Psychological intervention for preventing and treating depression is necessary.  </div> Psychological Stress, Depression, Socialsupport, Coping Skills, Locus of Control, Gastrointestinal Cancers, Quality of Life 23 29 http://jccs.yums.ac.ir/browse.php?a_code=A-10-1-72&slc_lang=en&sid=1 M. Malekzadeh 10031947532846005421 10031947532846005421 No Social Determinant of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran N. Hashemi Mohammad Abad 10031947532846005422 10031947532846005422 No Department of Psychiatry, Faculty of Medicine, Yasuj University of Medical sciences, Yasuj, Iran Sh. Vazir s_vazir@hotmail.com 10031947532846005423 10031947532846005423 Yes National Institute of Nutrition (ICMR), Hyderabad, India