Journal of Clinical Care and Skills

en Filter-Based Feature Selection for Type II Diabetes Prediction Diagnosis Skills Diagnosis Skills توصيفی و نظرسنجی Descriptive Study Aims: Type 2 diabetes mellitus is a major global health challenge, and early prediction is key to prevention. This study compared three filter-based feature selection methods (ANOVA (f-classif), mutual information, and Chi-square test) for identifying predictors of type 2 diabetes and assessed their impact on the performance of logistic regression. Instrument & Methods: This retrospective study analyzed data from 3,203 adults aged 35-70 years from Yasuj, Kohgiluyeh and Boyer-Ahmad Province, Iran, gathered between 2020 and 2022 in the Dena-PERSIAN cohort, including 402 (12.55%) individuals with type 2 diabetes. Preprocessing included imputation, normalization, and class balancing using the synthetic minority oversampling technique. Each method ranked predictors, and the top five features were used to train logistic regression models. Model performance was evaluated on a test set using accuracy, precision, recall, and F1-score. Findings: Fasting blood sugar and age consistently emerged as dominant predictors across methods. ANOVA highlighted metabolic factors (triglycerides, fatty liver, and kidney stones), while mutual information emphasized high-density lipoprotein cholesterol and lifestyle behaviors, and the Chi-square test prioritized categorical comorbidities. Logistic regression achieved the strongest performance with ANOVA and mutual information (accuracy and F1=0.84), slightly outperforming the Chi-square test (accuracy and F1=0.82). Conclusion: ANOVA and mutual information produced clinically meaningful and stable feature subsets for type 2 diabetes prediction, centered on fasting glucose, age, and fatty liver. Type 2 Diabetes,Life Style,ANOVA,Chi-Square Test,Logistic Regression, 121 128 http://jccs.yums.ac.ir/browse.php?a_code=A-10-331-1&slc_lang=en&sid=1 M. Ghaderzadeh 10031947532846006121 10031947532846006121 No Department of Medical Informatics, Boukan School of Medical Sciences, Urmia University of Medical Sciences, Urmia, Iran C. Salehnasab 10031947532846006122 10031947532846006122 Yes Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran