en Mental Health Mental Health پژوهشی اصيل Original Research <span style="font-size:12pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#8496b0">Aims:</span></span></span></strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> This study aimed to investigate the effect of reducing frontal head temperature on visual attention accuracy and cognitive performance in patients with schizophrenia.</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#8496b0">Materials & Methods:</span></span></span></strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> This double-blind clinical trial was conducted on 42 hospitalized patients with schizophrenia at Shahid Rajaee Hospital in Yasuj, Iran. Participants were selected through convenience sampling and randomly assigned, using block randomization, to equal intervention and control groups. In the intervention group, prefrontal cortical temperature was lowered, whereas the control group received a sham intervention. The Rapid Visual Information Processing test was used to assess visual attention, and the Flicker Fusion test was applied to evaluate cognitive function. Measurements were obtained before and immediately after the intervention. Data were analyzed using SPSS 25 with independent t-tests and repeated-measures ANOVA at a significance level of p<0.05.</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#8496b0">Findings:</span></span></span></strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"> The mean age of participants was 22.16&plusmn;2.18 years. No significant demographic differences were found between the groups. After the intervention, the intervention group showed significant improvements in both visual attention and cognitive performance compared with the control group (p<0.001).</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif"><span style="color:#8496b0">Conclusion:</span></span></span></strong><strong> </strong><span style="font-size:10.0pt"><span style="font-family:&quot;Cambria&quot;,serif">Cooling the prefrontal cortex effectively modulates cerebral blood flow and neurophysiological activity, leading to improved attention and cognitive function in patients with schizophrenia.</span></span></span></span> Attention,Cerebrovascular Circulation,Cognition,Prefrontal Cortex,Schizophrenia,Visual Perception, 225 232 http://jccs.yums.ac.ir/browse.php?a_code=A-10-172-5&slc_lang=en&sid=1 S. Mohsenian 10031947532846006427 10031947532846006427 No Department of Ergonomic and Occupational Therapy, Rajaee Hospital, Yasuj, Iran I. Yazdanpanah 10031947532846006428 10031947532846006428 No College of Medicine, Zhejiang University of Medical Sciences, Zhejiang, China N. Hashemimohammadabad 10031947532846006429 10031947532846006429 No Department of Psychiatry, College of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran Z. Sadat 10031947532846006430 10031947532846006430 No Department of Psychiatry, College of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran Z. Hashemimohammadabad 10031947532846006431 10031947532846006431 Yes College of Medicine, Zhejiang University of Medical Sciences, Zhejiang, China