en پژوهشی اصيل Original Research <strong>Aims</strong>: Chronic non-specific low back pain is the most common chronic lower back pain, and developing a therapeutic and rehabilitative plan to more rapidly mend patients with lower back pain has always been discussed. The present study aimed to determine the effect of prayer-based movements on pain and endurance of flexor muscles in patients with non-specific chronic low back pain.<br> <strong>Materials & Methods:</strong> This quasi-experimental study was conducted on all the patients with a chronic non-specific LBP referring to Shahid Mofatteh Clinic No. 1 in Yasuj, 2020. According to block random assignment, Sixty-six patients were divided into two groups of the intervention and control. In the intervention group, prayer-based exercises were performed three sessions a week for eight weeks. The control group was not instructed. The demographic questionnaire and Quebec back pain disability scale were used to measure pain, and the maintain the 60&deg; angle test was used to collect data before intervention; the visual pain measurement scale was used immediately after the intervention, and the endurance test of spine flexor muscles performed at the angle of 60&deg; was used a week after the intervention. The collected data were analyzed by SPSS 21 using descriptive statistics and statistical tests of Paired T, Mann-Whitney, Independent T, Wilcoxon, Chi-square, and Shapiro-Wilk.<br> <strong>Findings:</strong> There was no significant difference between the two groups in terms of pain severity and endurance of the flexor muscles at the starting point (p>0.05). The comparisons of the mean immediately and a week after the intervention were significant (p<0.05).<br> <strong>Conclusion:</strong> Prayer-based exercises effectively affect pain severity and endurance of flexor muscles in patients with non-chronic lower back pain. Exercise, Prayer, Pain, The Endurance of Flexor Muscles, Chronic Non-Specific Lower Back Pain 57 61 http://jccs.yums.ac.ir/browse.php?a_code=A-10-127-1&slc_lang=en&sid=1 A. Jokarborzabad 10031947532846005575 10031947532846005575 No Department of Medical Surgical Nursing, School of Nursing, Yasuj University of Medical Sciences, Yasuj, Iran Z. Karimi 10031947532846005576 10031947532846005576 No Department of Operating Room, School of Paramedicine, Yasuj University of Medical Sciences, Yasuj, Iran P. Yazdanpanah 10031947532846005577 10031947532846005577 No Department of Physical Medicine and Rehabilitation, School of Medi-cine, Yasuj University of Medical Sciences, Yasuj, Iran N. Roustaei 10031947532846005578 10031947532846005578 No Department of Medical Surgical Nursing, School of Nursing, Yasuj University of Medical Sciences, Yasuj, Iran S. Mohammadhossini hossini2370@yahoo.com 10031947532846005579 10031947532846005579 Yes Department of Biostatistics and Epidemiology, School of Health and Nutrition Sciences, Yasuj University of Medical Sciences, Yasuj, Iran