2026-08-08T15:08:15+03:30 http://jccs.yums.ac.ir/browse.php?mag_id=26&slc_lang=en&sid=1

26-376 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 A. Marzban This article has no abstract. This article has no keywords. 2025 4 01 57 58 http://jccs.yums.ac.ir/article-1-376-en.pdf 10.58209/jccs.6.2.57

26-397 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 Z. Hashemimohammadabad M. Hashemimohammadabad I. Yazdanpanah D. Razmjoue F. Karimi N. Hashemimohammadabad Aims: The aim of this study was to determine the effectiveness of the hydrolyzed extract from Melissa officinalis in patients with depression who are taking escitalopram. Materials & Methods: This quasi-experimental using pre-test and post-test phases, assessed 78 patients in 2023. The participants were divided into two groups of 39. In the control group, escitalopram (10mg daily, single tablet) was prescribed for 30 days, while in the intervention group, escitalopram (10mg daily, single tablet) and Melissa officinalis hydrochloride capsules (500mg daily, single tablet) were prescribed for 30 days. Depression was measured using the Hamilton Depression Rating Scale and the Beck Depression Inventory. For data analysis, chi-square tests, paired t-tests, and independent t-tests with a significance level of 0.05 were employed, using SPSS version 26. Findings: Regarding demographic factors, there was no statistically significant difference in treatment rates between the intervention and control groups. There was no significant difference between the two groups in the severity of depression, as measured by the Beck and Hamilton scales in the pre-test (p=0.533, p=0.570). The severity of depression decreased significantly (p<0.001) in both groups in the post-test, but the severity of depression on both scales decreased significantly (p<0.001) in the intervention group after the intervention. Conclusion: The extract of Melissa officinalis is effective in reducing symptoms of depression when used in combination with the medication escitalopram.   Depression Dracocephalum Kotschyi Escitalopram 2025 4 01 59 64 http://jccs.yums.ac.ir/article-1-397-en.pdf 10.58209/jccs.6.2.59

26-404 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 M. Zoladl M.S. Mousavi M.L. Rastian F. Tabatabaei M. Salari Aims: Patient safety is one of the fundamental pillars of healthcare and plays a crucial role in the quality of nursing services. Promoting a culture of safety can enhance nurses’ professional behavior and help prevent medical errors. Therefore, this study was conducted to determine the effect of patient safety culture on nurses’ professional behavior. Materials & Methods: In this randomized field trial, 84 eligible nurses from hospitals in Yasuj were randomly assigned to intervention and control groups using block randomization. Data on the professional behavior of the nurses were collected both before the intervention and one month afterward. The collected data were analyzed using SPSS version 21, with a 95% confidence level. Chi-square tests, independent t-tests, and paired t-tests were used for statistical analysis. Findings: After the intervention, there was a statistically significant difference in the overall professional behavior scores between the intervention and control groups, with mean scores of 96.40±12.70 and 52.00±9.40, respectively (p<0.0001). Conclusion: The implementation of patient safety culture has a significant and positive impact on nurses’ professional behavior. Patients Safety Culture Behavior Nurses 2025 4 01 65 69 http://jccs.yums.ac.ir/article-1-404-en.pdf 10.58209/jccs.6.2.65

26-401 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 F. Goudarzi F. Hekmatzadeh Aims: This study aimed to systematically review clinical trials of herbal products on the severity of menstrual bleeding. Information & Methods: In this review, all articles that employed clinical trial methods in the field of “effectiveness of herbal compounds in the treatment of heavy menstrual bleeding” were searched without a time limit until October 2024. Persian and English sources, as well as search engines including PubMed, Cochrane, Web of Science, Scopus, Magiran, and SID Iranmedex, were reviewed. Keywords based on MeSH, which included menstrual bleeding, herbal medicine, complementary medicine, and alternative care, were used for the search. The AND and OR operators were utilized in the search. These databases were searched without a time limit until October 2024. Findings: Out of 28,108 articles, 16 articles were reviewed. Most of the herbs examined reduced menstrual bleeding. The results of several studies on the effects of ginger, chamomile, and fennel in reducing menstrual bleeding were consistent. Conclusion: The medicinal products prepared in all studies were reported to be effective in reducing menstrual bleeding. Due to the insufficient number of articles on the herbs reviewed, further studies with different forms and doses are necessary to achieve reliable results and determine the effective dose and form of these herbs. Menstruation Menorrhagia Systematic Review Plants Plants Medicinal 2025 4 01 71 82 http://jccs.yums.ac.ir/article-1-401-en.pdf 10.58209/jccs.6.2.71

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Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 G. Rezaei F. Salmani Aims: Coronary artery bypass grafting is a recommended and effective treatment for some heart patients. Among its psychological complications, death anxiety is one of the most common. Various factors can influence the development and severity of this anxiety. This study aimed to investigate death anxiety and its related factors in patients scheduled for coronary artery bypass grafting. Instrument & Methods: This descriptive-correlational study was conducted at Shariati Hospital in Isfahan in 2024. A total of 100 coronary artery bypass grafting candidates admitted to the cardiac intensive care unit were selected through convenience sampling. After obtaining informed consent, participants were instructed to complete a questionnaire, which consisted of two parts, including demographic data and Templer’s Death Anxiety Scale. Data were analyzed using SPSS version 20 through descriptive statistics and the Pearson correlation coefficient. Findings: The overall level of death anxiety in patients was moderate. There was a significant relationship between death anxiety and parameters, such as age, sex, marital status, employment, and the presence of underlying disease (p≤0.05). However, no significant relationship was found with place of residence (urban/rural), education level, or duration of illness (p>0.05). Conclusion: Death anxiety is influenced by various factors, such as age, gender, employment status, marital status, and religious beliefs. Death Anxiety Death Coronary Artery Bypass 2025 4 01 83 88 http://jccs.yums.ac.ir/article-1-396-en.pdf 10.58209/jccs.6.2.83

26-419 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 S.M.H. Mousavi M. Hosseinian M. Rezaei Aims: Intravenous cannulation is a common invasive procedure that causes pain, anxiety and technical challenges in both adults and children. This study evaluated nurses’ Intravenous cannulation skills and related influencing factors at Kashan University of Medical Sciences hospitals. Instrument & Methods: In this descriptive observational study, which is conducted in 2024 in Kashan, 253 nurses working in hospitals affiliated with Kashan University of Medical Sciences  were investigated. A non-probability quota sampling method was used. Data were collected using questionnaires on the demographic information of nurses and patients, along with a researcher-made checklist for evaluating the nurses’ clinical Intravenous cannulation skills. Data analysis was performed using SPSS version 26, employing statistical tests such as the independent t-test, analysis of variance (ANOVA), Pearson correlation, and multiple regression. Findings: The mean total score for the nurses’ Intravenous cannulation skills was 33.73±8.33, which corresponded to 84.2% of the maximum score (40 points). Over 90% of the nurses rated their Intravenous cannulation skills as good to excellent. The average duration of the cannulation process was 85.4±13.6 minutes. Moreover, the mean Intravenous cannulation skill score for nurses in the emergency department was significantly lower than that in other departments (p<0.05). Conclusion: About 90% of nurses met Intravenous cannulation standards; targeted training to address gaps could further boost their skills, improve patient outcomes, and cut hospital stays and costs. Clinical Skills Venipuncture Nurses Nursing Education 2025 4 01 89 95 http://jccs.yums.ac.ir/article-1-419-en.pdf 10.58209/jccs.6.2.89

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Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 M.A. Fazeli M. Malekzadeh H. Bayatmanesh P. Neysarian N. Arefkhah M. Sedaghattalab Aims: Despite the urgent need to treat the COVID-19 pandemic, no effective treatment has been identified to date. The present study aimed to compare the effects of interferon Beta-1 and dexamethasone on the treatment of hospitalized COVID-19 patients. Materials & Methods: This phase 2, open-label, randomized trial examined adult patients who were admitted to hospitals in Yasuj, Iran, from October 2021 to May 2022 due to COVID-19. Patients were randomly assigned to intervention group 1 (88 patients), which included remdesivir, interferon beta-1, and dexamethasone, and intervention group 2 (88 patients), which included remdesivir and dexamethasone, in a ratio of 1:1. The mean arterial blood O2 saturation and length of hospitalization for both groups were compared. Findings: The two groups did not show a significant difference in terms of demographic characteristics and disease-related parameters at baseline (p>0.05). The mean O2 saturation at the time of discharge for group 1 (90.14±10.72) and group 2 (92.54±3.19) demonstrated a significant difference (p<0.05). The mean length of hospitalization for group 1 (7.02±2.56) and group 2 (5.73±2.04) was significantly different (p<0.01). There was a significant difference between the number of deaths in group 1 (7 patients) and group 2 (0 patients; p<0.01). Conclusion: The administration of remdesivir and dexamethasone, compared to remdesivir, dexamethasone, and interferon, results in a decreased length of hospitalization, reduced mortality, and improved O2 saturation. Patients Interferons Dexamethasone COVID-19 2025 4 01 97 103 http://jccs.yums.ac.ir/article-1-403-en.pdf 10.58209/jccs.6.2.97

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Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2025 6 2 Z. Asadikalameh F. Golshahi Chamandani M. Sharifi Aims: Fetal heart rate patterns are monitored throughout pregnancy and labor to evaluate the health of the fetus. We aimed to evaluate the impact of sildenafil on fetal heart rate patterns during delivery. Materials & Methods: This single-blind randomized controlled trial was conducted on 198 participants in the maternity unit of Imam Sajjad Hospital, Yasuj, in 2024. In addition to standard practices during labor, the intervention group received oral sildenafil at a dose of 50mg every 8 hours, not exceeding 150mg, starting with the initial dose at the onset of the study. In the control group, standard routine care was implemented. The primary outcome measure was fetal heart rate patterns, while the secondary outcome measures included labor duration, meconium-stained amniotic fluid, delivery method, postpartum hemorrhage, Apgar score, admission to the neonatal intensive care unit, and adverse effects. Findings: Ninety-six cases in the sildenafil group and 102 cases in the control group were included in the analysis. The reassuring fetal heart rate pattern was more common in the sildenafil group (80.2% vs. 56.9%). Among the various non-reassuring fetal heart rate patterns, tachycardia and bradycardia were more prevalent in the control group than in the sildenafil group. Cesarean sections occurred more frequently in the control group than in the sildenafil group. The neonatal outcomes were similar in both groups, and no side effects were reported. Conclusion: Sildenafil improves non-reassuring fetal heart rate patterns, especially tachycardia and bradycardia, and decreases the rate of cesarean deliveries.   Sildenafil Fetal Heart Clinical Trial Labor Obstetric 2025 4 01 105 111 http://jccs.yums.ac.ir/article-1-400-en.pdf 10.58209/jccs.6.2.105