2026-08-08T13:39:46+03:30 http://jccs.yums.ac.ir/browse.php?mag_id=4&slc_lang=en&sid=1

4-71 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 H. Mohammadi M. Afkari N. Salehi A. Roozbehi amroozbehi@gmail.com Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy. Materials & Methods: In this clinical trial, 90 patients with lumbosacral radiculopathy referring to the clinic of Shahid Mofatteh, Yasuj, Iran in 2018, were selected using purposeful convenience sampling and divided into intervention (N=45) and control (N=45) groups. The pain severity was assessed by a standard visual analog scale (VAS). In the intervention group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin, and in the control group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin placebo were prescribed. After 8 weeks, the severity of the pain was again assessed and compared. Findings: At the beginning of the study, the mean pain severity in the intervention and control group did not differ significantly (p>0.05). After the intervention, the mean pain severity between the two groups did not show a significant difference (p>0.05). The severity of the pain did not differ significantly between the two groups of intervention and control according to age, disease history, location of pain, and body weight (p>0.05). Conclusion: The efficacy of pregabalin and NSAID in comparison with NSAID use in patients with lumbosacral radiculopathy is not different in reducing pain severity.Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.   Radiculopathy Pregabalin Lower Back Pain Lumbosacral Region 2020 7 01 153 157 http://jccs.yums.ac.ir/article-1-71-en.pdf 10.52547/jccs.1.4.153

4-77 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 R. Vanda Sh. Aramesh M. Sadeghian M.A. Ghatee P. Ghaffari pari.ghaffari@gmail.com Aim(s): Obesity in pregnant women is a serious health problem that has many complications such as pre-eclampsia and fetal growth restriction (FGR). The aim of the present study was to evaluate the effect of aspirin on prevalence of pre-eclampsia and FGR in obese pregnant women. Materials & Methods: This randomized controlled clinical trial was conducted on 187 pregnant women referring to birth center of Mofatteh Clinic, Yasuj University of Medical Sciences, Yasuj, Iran in 2017-2018. The subjects were selected using purposive sampling method and randomly divided into two groups; intervention group (n=89) and control group (n=98). The intervention group received 80mg/day aspirin and the control group received placebo at 13-20 weeks of gestation until 34 weeks of pregnancy. Data were analyzed by SPSS 21 software using Chi square test. Findings: The prevalence of pre-eclampsia (1.1 vs. 11.2) and FGR (3.4 vs. 21.4) were significantly lower in the intervention group compared to the control group (p<0.05). Conclusion: Administration of 80mg/daily of aspirin from 13-20 weeks of gestation in obese pregnant women reduces the incidence of pre-eclampsia and FGR, which could support the positive role of aspirin in preventing pre-eclampsia and FGR. aspirin obesity pregnancy preeclampsia fetal growth restriction 2020 7 01 159 164 http://jccs.yums.ac.ir/article-1-77-en.pdf 10.52547/jccs.1.4.159

4-73 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 S.F. Hekmatzadeh sf.hekmatzadeh@yahoo.com Sh. Aramesh S. Baashti Aim(s): To advance birth and avoid prolonged labor, oxytocin is routinely used globally. However there are a number of side-effects in this therapy. The aim of this study was to evaluate the effect of boiled Anethum graveolens seed on the duration and intensity of labor pain in comparison to oxytocin. Materials & Methods: This randomized clinical trial was conducted on 88 pregnant women admitted to the birth center of Imam Sajjad, Yasuj hospital, Iran in 2015-2016. The subjects were selected by purposive sampling method and randomly allocated to Anethum graveolens (n=41) and oxytocin (n=47) groups. In Anethum graveolens group, 10gr of Anethum graveolens seed was boiled in 100ml of water for 10 minutes and, after filtration, was given to participants to swallow at the start of active labor. In oxytocin group, 10 units of oxytocin in 1000ml of Ringer’s solution was diluted and administered by infusion when the contractions were established. Data were analyzed by SPSS 21 software using chi square, Mann-Whitney U and independent t test. Findings: Labor was shorter in the first, second and third stages in Anethum graveolens group compared to oxytocin group. However there was a significant difference only in the 1st stage of labor (p<0.001). The dilatation and effacement scores improved in Anethum graveolens group than the oxytocin group (p<0.05) at one, two, three, and four hours of continuous intervention. Conclusion: Using boiled Anethum graveolens seed can be effective in reducing the length of labor and improving dilatation and effacement during birth. dill seeds oxytocin labor pain 2020 7 01 165 170 http://jccs.yums.ac.ir/article-1-73-en.pdf 10.52547/jccs.1.4.165

4-78 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 A. Keshtkari A. Mehboudi arm.mehboudi@yahoo.com M.A. Ghatee N. Bagheri Aims: Breastfeeding is an economic and valuable method to protect infant health during the life and provides unique biological and emotional effect for mothers and infants. The aim of this study was to compare the effect of fennel on maternal serum prolactin level and neonatal weight gain to effect of domperidon and placebo on these variables. Materials & Methods: In this single blind randomized clinical trial (RCT), 150 volunteer mothers who had delivery and their newborns in Imam Sajad Hospital of Yasuj University of Medical Science, Yasuj, Iran in 2018, were selected by convenience sampling method and randomly assigned into three equal groups: placebo, domperidone, and fennel groups. Participants used placebo, domperidone tablets and fennel seeds powder for 14 days. Serum prolactin levels of mothers were measured with ELISA method before and after interventions. The weight of newborns were measured using digital scales on birth day, 14th and 28th days of study. Data were analyzed by SPSS 21 software using Chi square test, paired t-test, and one-way ANOVA. Findings: The mean serum prolactin level of the mothers before and after intervention in all three groups were not significantly different (p>0.05). The mean weight of neonates on the birth day, 14th day and 28th day in three groups did not show any significant difference (p>0.05). Conclusion: Fennel and domperidone have no effect on the serum prolactin level of lactating mothers and weight gain of newborns. Fennel Prolactin Domperidone Breastfeeding Lactation 2020 7 01 171 174 http://jccs.yums.ac.ir/article-1-78-en.pdf 10.52547/jccs.1.4.171

4-69 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 F. Mahmoudi fatemeh.mahmoodii66@yahoo.com P. Ghaffari R. Hosseinpour Aims: Pelvic floor disorders such as urinary incontinence and pelvic and genital prolapse affect sexual function and quality of life. The aim of the present study was to compare the effect of anterior colporrhaphy and transobturator tape (TOT) surgeries on urinary incontinence and sexual function in women. Materials & Methods: This retrospective cohort clinical trial study was performed on 136 women with pelvic prolapse and urinary incontinence who referred to Shahid Mofatteh Women's Clinic in Yasuj, Iran, from 2016 to 2018. All patients in the two groups of 68 underwent anterior colporrhaphy and TOT surgeries. Non-random sampling method was performed. Data were collected by Pelvic Organ Prolapse Incontinence Sexual Questionnaire (PISQ) and Female Sexual Function Index (FSFI) before and 6 months after surgery, and analyzed using SPSS 20 software through Chi-square test, independent t-test and paired t-test. Findings: 77.9% of women had urinary incontinence or leakage during sneezing, coughing, or sexual intercourse, which improved by 95.6% after surgery. The variables of the PISQ questionnaire were significantly different in terms of behavior and emotions and physical factors, before and after TOT and anterior colporrhaphy surgeries (p<0.05). The average total score of women's sexual function before and after surgery did not show a significant difference (p>0.05). In the TOT surgery group, a significant increase was observed in the areas of sexual desire, sexual arousal, orgasm, and sexual satisfaction after surgery. Conclusion: TOT and anterior colporrhaphy surgeries are effective in relieving urinary incontinence, but TOT surgery is more effective in the long term.   Anterior Colporrhaphy Trans-obturator Tape Urinary Incontinence Sexual Behavior Sexual Satisfaction 2020 7 01 175 180 http://jccs.yums.ac.ir/article-1-69-en.pdf 10.52547/jccs.1.4.175

4-81 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 K. Karimzadeh Shirazi Sh. Davoodi M. Akbartabar Toori m_akbartabar@yahoo.co.uk Aims: The goal of this study is to investigate  the impact of teaching on the health belief model constructs in the preventive  behaviors of metabolic syndrome in premenopausal women over  40  years of Gachsaran. Methods:  130 females who visited health and treatment centers were divided into two groups of control and intervention.  The instrument for gathering data was a questionnaire containing demographic information, anthropometric measurement and questions related to the health belief model. After doing the pretest in both groups, only the intervention group was given  instruction on preventive behaviors of metabolic syndrome disease. The collected data were analyzed using a Paired T-test and independent T-test. SPSS (22) was used to analyze the data Findings: Despite the fact that the two groups were similar at the beginning of the study, after giving the teaching, a significant difference of perceived susceptibility,  perceived severity, perceived benefits,   perceived barriers,   perceived self-efficacy and knowledge in the intervention group. A significant difference was also observed in both groups with respect to cues to action.  Conclusion: The findings of this study indicated the impact of educational intervention on women's beliefs, thus it can be suggested that an educational program based on the Health Belief Model be used to prevent this disease.    Educational Intervention Health Belief Model Metabolic Syndrome Women Premenopause 2020 7 01 181 187 http://jccs.yums.ac.ir/article-1-81-en.pdf 10.52547/jccs.1.4.181

4-80 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 A. Arya S. Jokar P. Etemadfar J.M. Malekzadeh R. Jannesar M. Rohani T. Mohamadi F. Kharaman M. Yosefi S. Hatamipour A. Roozbehi amroozbehi@gmail.com Aims: Patients with thalassemia major suffer from iron overload due to excessive cell lysis. Iron-chelating agents are used to preventing the effects of iron overload on the body. Deferoxamine, deferiprone, and deferasirox are the most common iron-chelating agents. The aim of this study was to compare deferoxamine, deferiprone, and deferasirox iron-chelating agents in reducing serum ferritin levels in patients with thalassemia major. Instrument & Methods: This descriptive cross-sectional study was performed on 114 thalassemia major patients in the Cooley's ward of Shahid Beheshti Hospital, Yasuj, Iran, in 2018 who had been taking iron supplements for the past year. Census sampling was done. After recording patients’ information, such as age, sex, and type of iron used, the blood sample was taken from the patients to measure serum ferritin and the results were analyzed using SPSS 22 software and multivariate analysis of variance. Findings: The mean serum ferritin level was 3438.70±2872.88 ng/ml. 14 patients were taking deferoxamine, 62 patients were using deferiprone, and 38 patients were consuming deferasirox. There was no significant difference between iron-chelating agents in reducing ferritin levels (p>0.05). Also, there was no significant difference between males and females in terms of decreased ferritin levels (p>0.05). Conclusion: There is no difference between deferoxamine, deferiprone and deferasirox iron-chelating agents in reducing the ferritin levels of patients with thalassemia and all can be administrated considering the cost, availability, condition, and patient's desire. Thalassemia Major Iron Chelating Agents Deferoxamine Deferiprone Deferasirox Ferritin 2020 7 01 189 193 http://jccs.yums.ac.ir/article-1-80-en.pdf 10.52547/jccs.1.4.189

4-72 2026-08-08 10.1002

Journal of Clinical Care and Skills J Clinic Care Skill 2645-7687 2645-7687 10.58209/jccs 2020 1 4 Z. Daneshyar shadi_med79@yahoo.com H. Abidi Introduction: Endometriosis, commonly occurs in the pelvic organs, mostly the ovaries, with dysmenorrhea, and menorrhagia. Umbilical endometriosis is rare. Symptoms include umbilical masses with swelling and pain. So it is often not recognized based on its clinical appearance. In this report, it was presented a case of primary umbilical endometriosis, accidentally found after surgery for umbilical hernia and detected in pathologic examination of tissue. Patient Information: A 32-year old female, was presented with umbilical bulging and mild cyclic umbilical pain, without history of abdominal surgery, or symptom of pelvic endometriosis. Umbilical sonography was done in favor of fixed sac of herniation, underwent surgery, umbilical endometriosis accidentally found in pathologic examination after surgery for umbilical hernia. Conclusion: Although endometriosis is a common gynecological disease, primary umbilical endometriosis is a rare entity that make the diagnosis is difficult. Nevertheless, this disease must be considered in the differential diagnosis of any suspected umbilical mass. Umbilical Endometriosis Umbilicus Pain Pathology 2020 7 01 195 197 http://jccs.yums.ac.ir/article-1-72-en.pdf 10.52547/jccs.1.4.195