R. Kazemi Dermenaki Farahani , K. Rahzani, D. Hekmat Pu, A. Rostami, Volume 4, Issue 4 (Fall 2023)
Abstract
Aims: Burns and wounds caused by it are a global injury. Finding natural ingredients to accelerate wound healing in patients with fewer side effects could be valuable. This study aimed to determine the effect of oral Centella asiatica extract on the healing of pain and wound of burn in patients. Materials & Methods: This study is a clinical trial in which 76 patients hospitalized in the burn department were randomly divided into two intervention (n=38) and control (n=38) groups. The intervention group, in addition to the usual antibiotic treatments, received capsules containing 200mg of Centella asiatica twice daily, and the control group received capsules containing 200mg of starch twice daily. Data collection tools were Bates-Jensen Wound Assessment tool and Visual Analog Scale. Patients' pain and wound healing status were examined at different time of the study. Findings:The mean burn pain score showed a significant improvement in the intervention group compared to the control group (p<0.001). The average wound healing score did not show significant improvement in the intervention group compared to the control group (p=0.561). However, size (p=0.023), the degree of destruction of the underlying tissues (p=0.032), the amount of necrotic tissue (p=0.015), and the amount of granulation tissue (p=0.001) improved significantly in the intervention group. In addition, the peripheral tissue edema in the control group decrease significantly compared to the intervention group (p=0.008). Conclusion:Oral extract of Centella asiatica reduces pain in burn patients. However, it does not affect wound healing, although it improves some wound healing indicators.
A. Sasani, K. Rahzani, D. Hekmatpou, F. Haghverdi , Volume 5, Issue 2 (Spring 2024)
Abstract
Aims: Hemodialysis is the most common treatment method for patients, and access to blood vessels is the way to save hemodialysis patients. Therefore, the purpose of this study was to compare the effect of Hugo point cold therapy with the needle insertion site on pain caused by venipuncture in hemodialysis. Material & Methods: This randomized clinical trial was carried out on hemodialysis patients of Hami Arak Dialysis Center in Arak, Iran. The samples were selected by purposive sampling (n=56) and assigned into two groups (28 samples each). For group A, an ice pack was used at the needle entry sites, and for group B, an ice pack was used at the Hugo point of the opposite hand for 10 minutes before cannulation by a nurse. The pain intensity of the patients was measured within 1 minute after cannulation and recorded based on the visual comparison scale of pain measurement (VAS). Data was analyzed using SPSS 23 software. Findings:The average pain in groups A and B were 3.10±86.81 and 4.2±65.05, respectively. There was no significant difference in the average pain intensity between the two cold therapy groups at the needle insertion site and Hugo point (p>0.05). Conclusion: Cryotherapy intervention at the needle insertion site and Hugo's point have the same effect on reducing arteriovenous fistula cannulation pain.
