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Volume 2, Issue 3 (2021)
J Clinic Care Skill 2021, 2(3): 151-155 |
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Received: 2021/06/4 | Accepted: 2021/09/12 | Published: 2021/09/12
Received: 2021/06/4 | Accepted: 2021/09/12 | Published: 2021/09/12
How to cite this article
Razmjoue D, Khoramrooz S S, Jafari Lagharaki M, Jafari Lagharaki S, Nooripour Sisakht S, Zoladl M et al . Prevalence of Positive Fungal Cultures in Patients with Chronic Sinusitis undergoing Functional Endoscopic Sinus Surgery in Yasuj, Iran. J Clinic Care Skill 2021; 2 (3) :151-155
URL: http://jccs.yums.ac.ir/article-1-109-en.html
URL: http://jccs.yums.ac.ir/article-1-109-en.html
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Authors
D. Razmjoue1, S. S. Khoramrooz2, M. Jafari Lagharaki3, S. Jafari Lagharaki3, S. Nooripour Sisakht2, M. Zoladl4, Gh.A. Sabz *5
1- Department of Basic Sciences, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
2- Department of Microbiology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
3- Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran
4- Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
5- Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
2- Department of Microbiology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
3- Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran
4- Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
5- Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
Abstract (1889 Views)
Aims: Sinusitis is the inflammation of the nasal cavity, and Paranasal sinuses occur by pathogen agents such as bacteria, viruses, fungi, or other allergens. This study was aimed to determine the prevalence of positive fungal cultures in patients with chronic sinusitis undergoing functional endoscopic sinus surgery.
Materials & Methods: This experimental study was carried out on 60 patients with chronic sinusitis in 2019. After anesthesia in the operating room, the ENT specialist evacuated the sinuses of patients with chronic sinusitis undergoing sinus endoscopic surgery. After sampling of evacuated sinus tissue of eligible patients and transfer to mycology laboratory, fungal elements were identified using direct smear and culture of the sample on sub-dextrose agar medium. The patient's profiles were recorded. Data were analyzed using SPSS 21 software by the descriptive statistic.
Findings: 36 of selected patients with chronic sinusitis were male (60%), and 24 were female (40%) with a mean age of 38.4±11.5 years. Two Candida parapsilosis (3.3%), one Aspergillus flavus (1.7%), and one Aspergillus niger (1.7%) were detected. Therefore, the prevalence of positive fungal cultures in patients with chronic sinusitis undergoing endoscopic sinus surgery was 6.7% in Yasuj, southwest of Iran, in 2019.
Conclusion: The prevalence of fungal sinusitis is low in patients with chronic sinusitis in Yasuj due to the location of Yasuj in a mountainous region with a cold and dry climate.
Materials & Methods: This experimental study was carried out on 60 patients with chronic sinusitis in 2019. After anesthesia in the operating room, the ENT specialist evacuated the sinuses of patients with chronic sinusitis undergoing sinus endoscopic surgery. After sampling of evacuated sinus tissue of eligible patients and transfer to mycology laboratory, fungal elements were identified using direct smear and culture of the sample on sub-dextrose agar medium. The patient's profiles were recorded. Data were analyzed using SPSS 21 software by the descriptive statistic.
Findings: 36 of selected patients with chronic sinusitis were male (60%), and 24 were female (40%) with a mean age of 38.4±11.5 years. Two Candida parapsilosis (3.3%), one Aspergillus flavus (1.7%), and one Aspergillus niger (1.7%) were detected. Therefore, the prevalence of positive fungal cultures in patients with chronic sinusitis undergoing endoscopic sinus surgery was 6.7% in Yasuj, southwest of Iran, in 2019.
Conclusion: The prevalence of fungal sinusitis is low in patients with chronic sinusitis in Yasuj due to the location of Yasuj in a mountainous region with a cold and dry climate.
References
1. Shetty S, Chandrashekar S, Aggarwal N. A study on the prevalence and clinical features of fungal sinusitis in chronic rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2020;72(1):117-22. [DOI:10.1007/s12070-019-01769-w] [PMID] [PMCID]
2. Wiszniewska M, Walusiak-Skorupa J, Pannenko I, Draniak M, Palczynski C. Occupational exposure and sensitization to fungi among museum workers. Occup Med. 2009;59(4):237-42. [DOI:10.1093/occmed/kqp043] [PMID]
3. Wilson M, Wilson PJK. Chronic sinusitis. In: Wilson M, Wilson PJK. Close encounters of the microbial kind. Cham: Springer; 2021. [DOI:10.1007/978-3-030-56978-5_15]
4. Gendy S, Walsh MA, McConn-Walsh R, Costello RW. Recent consensus on the classification of rhinosinusitis-a way forward for research and practice. Surgeon. 2007;5(2):67-71. [DOI:10.1016/S1479-666X(07)80055-2]
5. Chang CC, Incaudo GA, Gershwin ME. Diseases of the sinuses: A comprehensive textbook of diagnosis and treatment. Amsterdam: Springer; 2014. [DOI:10.1007/978-1-4939-0265-1]
6. Ellis D, Davis S, Alexiou H, Handke R, Bartley R. Descriptions of medical fungi. Adelaide: University of Adelaide; 2007. [link]
7. Watkinson JC, Clarke RW. Scott-Brown's otorhinolaryngology and head and neck surgery. London: Tylor & Francis Group; 2018. [DOI:10.1201/9780429443558]
8. Soler ZM, Schlosser RJ. The role of fungi in diseases of the nose and sinuses. Am J Rhinol Allergy. 2012;26(5):351-8. [DOI:10.2500/ajra.2012.26.3807] [PMID] [PMCID]
9. Aribandi M, McCoy VA, Bazan C. Imaging features of invasive and noninvasive fungal sinusitis: A review. Radiographics. 2007;27(5):1283-96. [DOI:10.1148/rg.275065189] [PMID]
10. Chakrabarti A, Das A, Panda NK. Controversies surrounding the categorization of fungal sinusitis. Med Mycol. 2009;47 Suppl 1:299-308. [DOI:10.1080/13693780802213357] [PMID]
11. Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H, et al. Fungal rhinosinusitis: A categorization and definitional schema addressing current controversies. Laryngoscope. 2009;119(9):1809-18. [DOI:10.1002/lary.20520] [PMID] [PMCID]
12. Granville L, Chirala M, Cernoch P, Ostrowski M, Truong LD. Fungal sinusitis: Histologic spectrum and correlation with culture. Hum Pathol. 2004;35(4):474-81. [DOI:10.1016/j.humpath.2003.10.024] [PMID]
13. Taxy JB. Paranasal fungal sinusitis: contributions of histopathology to diagnosis: A report of 60 cases and literature review. Am J Surg Pathol. 2006;30(6):713-20. [DOI:10.1097/00000478-200606000-00006] [PMID]
14. Das A, Bal A, Chakrabarti A, Panda N, Joshi K. Spectrum of fungal rhinosinusitis: Histopathologist's perspective. Histopathology. 2009;54(7):854-9. [DOI:10.1111/j.1365-2559.2009.03309.x] [PMID]
15. Montone KT, Livolsi VA, Feldman MD, Palmer J, Chiu AG, Lanza DC, et al. Fungal rhinosinusitis: A retrospective microbiologic and pathologic review of 400 patients at a single university medical center. Int J Otolaryngol. 2012;2012:6848835. [DOI:10.1155/2012/684835] [PMID] [PMCID]
16. Deutsch PG, Whittaker J, Prasad S. Invasive and non-invasive fungal rhinosinusitis-a review and update of the evidence. Medicina. 2019;55(7):319. [DOI:10.3390/medicina55070319] [PMID] [PMCID]
17. Lawson W, Blitzer A. Fungal infections of the nose and paranasal sinuses: Part II. Otolaryngol Clin North Am. 1993;26(6):1037-68. [DOI:10.1016/S0030-6665(20)30743-X]
18. Stammberger H. Endoscopic surgery for mycotic and chronic recurring sinusitis. Ann Otol Rhinol Laryngol Suppl. 1985;119:1-11. [DOI:10.1177/00034894850940S501] [PMID]
19. Hadi U, Bitar M, Hachem R, Saade R, Husni R, Raad I. Fungal sinusitis in the immunocompetent patient: Risk factors and surgical management. Surg Infect. 2003;4(2):199-204. [DOI:10.1089/109629603766956997] [PMID]
20. Karthikeyan P, Coumare VN. Incidence and presentation of fungal sinusitis in patient diagnosed with chronic rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2010;62(4):381-5. [DOI:10.1007/s12070-010-0062-0] [PMID] [PMCID]
21. Badiei P, Gandomi B, Sabz GA, Jafarian H. A study on the frequency of fungal rhinosinusitis and to determine the sensitivity of the isolates to antifungal drugs in Shiraz, Iran 2012-2013. J Arak Univ Med Sci. 2015;18(3):1-8. [Persian] [link]
22. Fasunla AJ, Fayemiwo SA, Bakare RA, Ijaduola GTA. Aerobic bacteria and fungal isolates in maxillary sinusitis of adults in a resource poor environment. Afr J Clin Exp Microbiol. 2018;19(2):113. [DOI:10.4314/ajcem.v19i2.6]
23. Singh AK, Gupta P, Verma N, Khare V, Ahamad A, Verma V, et al. Fungal rhinosinusitis: Microbiological and histopathological perspective. J Clin Diagn Res. 2017;11(7):10-2. [DOI:10.7860/JCDR/2017/25842.10167] [PMID] [PMCID]
24. Collins MM, Nair SB, Wormald PJ. Prevalence of noninvasive fungal sinusitis in South Australia. Am J Rhinol. 2003;17(3):127-32. [DOI:10.1177/194589240301700303]
25. Awan NU, Cheema KM, Naumeri F, Qamar S. Allergic fungal rhino-sinusitis frequency in chronic rhino-sinusitis patients and accuracy of fungal culture in its diagnosis. Pak J Med Sci. 2020;36(3):555-8. [DOI:10.12669/pjms.36.3.1661]
26. Sharma S. Understanding allergic fungal rhino-sinusitis. Glob J Otolaryngol. 2018;13(3):1-6. [DOI:10.19080/GJO.2018.13.555865]
27. Irshad-ul-Haq M, Farooq M, Qadri SH. Prevalence of allergic fungal sinusitis among patients with nasal polyps. JSZMC. 2014;5(4):690-2. [link]
28. Rehman A, Rafiq F, Uppal AA. Evaluation of allergic fungal sinusitis occurrence in patients with nasal polyps. Pak J Med Health Sci. 2015;9(3):875-8. [link]
29. Singh S, Beena PM. Comparative study of different microscopic techniques and culture media for the isolation of dermatophytes. Indian J Med Microbiol. 2003;21(1):21-4. [link]
30. Sabz G, Gharaghani M, Mirhendi H, Ahmadi B, Gatee MA, Sisakht MT, et al. Clinical and microbial epidemiology of otomycosis in the city of Yasuj, southwest Iran, revealing aspergillus tubingensis as the dominant causative agent. J Med Microbiol. 2019;68(4):585-90. [DOI:10.1099/jmm.0.000948] [PMID]
31. Nowrozi H, Alavi S, Kazemi A, Razmpa E, Emami M, Oshaghi M. Fungus paranasal sinusitis in non- immunocompromised patients in Tehran, Iran (2006-07). J Gorgan Univ Med Sci. 2012;14(1):129-35. [Persian] [link]
32. Nikakhlagh S, Saki N. Functional endoscopic sinus surgery for fungal sinusitis (three years experience). Iranian J Otorhinolaryngol. 2004;16(3):36-41. [Persian] [link]
33. Hosseini SMS, Borghei P. Rhinocerebral mucormycosis: Pathways of spread. Eur Arch Otorhinolaryngol. 2005;262(11):932-8. [DOI:10.1007/s00405-005-0919-0] [PMID]
34. Parikh SL, Venkatraman G, DelGaudio JM. Invasive fungal sinusitis: a 15-year review from a single institution. Am J Rhinol. 2004;18(2):75-81. [DOI:10.1177/194589240401800202]
35. Suresh S, Arumugam D, Zacharias G, Palaninathan S, Vishwanathan R, Venkatraman V. Prevalence and clinical profile of fungal rhinosinusitis. Allergy Rhinol. 2016;7(2):115-20. [DOI:10.2500/ar.2016.7.0156] [PMID] [PMCID]
36. Rupa V, Jacob M, Mathews M, Job A, Kurien M, Chandi S. Clinicopathological and mycological spectrum of allergic fungal sinusitis in south India. Mycoses. 2002;45(9‐10):364-7. [DOI:10.1046/j.1439-0507.2002.00784.x] [PMID]
37. Saravanan K, Panda NK, Chakrabarti A, Das A, Bapuraj RJ. Allergic fungal rhinosinusitis: an attempt to resolve the diagnostic dilemma. Arch Otolaryngol Head Neck Surg. 2006;132(2):173-8. [DOI:10.1001/archotol.132.2.173] [PMID]
38. Chen CY, Sheng WH, Cheng A, Chen YC, Tsay W, Tang JL, et al. Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan. BMC Infect Dis. 2011;11:250. [DOI:10.1186/1471-2334-11-250] [PMID] [PMCID]