Volume 5, Issue 1 (2024)                   J Clinic Care Skill 2024, 5(1): 1001-1013 | Back to browse issues page

Ethics code: IR.ZUMS.REC.1398.208

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Zakerian Zadeh A, Dadashi M, Maghbooli M, zarei F, zakeryanzade R. Assessment of motor, cognition and depressive symptoms after transcranial direct current stimulation (tDCS) in ischemic stroke. J Clinic Care Skill 2024; 5 (1) :1001-1013
1-, Yasuj University of Medical Sciences
2- ,
3-, Zanjan University of Medical Sciences
Abstract:   (147 Views)
Aims: Stroke leads to many symptoms such as defects in motor, sensation, language and cognitive functions, which may help patients to recover sooner using complementary techniques. Therefore, this study was conducted with the aim of evaluating depression symptoms, motor learning and cognitive function after transcranial direct current stimulation (tDCS) in patients with ischemic stroke.
Methods and Materials: This study was a randomized controlled clinical trial that was conducted on patients with ischemic stroke in Zanjan city. 35 patients were randomly selected and randomly assigned to tDCS (12), Sham (12), Control (11) groups. The subjects were evaluated before, after the intervention and follow-up (one month after the post-test). The Fugl-Meyer Assessment (FMA), Hamilton depression symptoms test, Montreal cognitive assessment (MoCA) and Mini-Mental state examination (MMSE) were used for evaluation. The first group received consecutive anodal stimulation in M1damH + Left-DLPFC areas, 12 sessions of 60 minutes, and the second group received Sham-tDCS and the third group (control group) did not receive any intervention. Data were analyzed using descriptive statistics and multivariate covariance analysis using spss-23 software.
Findings: The average age of the patients (16 men and 8 women) was 64.12 years and most of them were men (66.7%). A significant difference was observed between the study groups after the intervention and one month later in motor function, depression symptoms and cognitive function (P=0.001). In the paired comparison, these differences were more between the tDCS group and each of the sham and control groups, but no significant difference was shown between the control and sham groups in these outcome variables.
Conclusion: tDCS leads to the improvement of motor learning, cognitive functions and depression symptoms of stroke patients and its effects remain significantly after the intervention.

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Article Type: Original Research | Subject: General
Received: 2023/12/18 | Accepted: 2024/03/1 | Published: 2024/03/12
* Corresponding Author Address: Zanjan University of Medical Sciences

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