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Volume 5, Issue 1 (2024)
J Clinic Care Skill 2024, 5(1): 25-31 |
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Received: 2024/01/16 | Accepted: 2024/02/6 | Published: 2024/02/21
Received: 2024/01/16 | Accepted: 2024/02/6 | Published: 2024/02/21
How to cite this article
Jamshidi H, Malekzadeh J, Afrasiabifar A, Alamdari A, Zamani Habibabad H, Hosseini N. Comparing the Effectiveness of Nutritional Education with and without Physical Activity on Blood Lipids and Liver Aminotransferase Enzymes in Non-Alcoholic Fatty Liver Diseased Men. J Clinic Care Skill 2024; 5 (1) :25-31
URL: http://jccs.yums.ac.ir/article-1-236-en.html
URL: http://jccs.yums.ac.ir/article-1-236-en.html
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Authors
H. Jamshidi1, J.M. Malekzadeh2, A. Afrasiabifar3, A.K. Alamdari *3, H. Zamani Habibabad3, N. Hosseini4
1- Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran
2- Department of Nutrition, School of Health and Nutrition, Yasuj University of Medical Sciences, Yasuj, Iran
3- Department of Nursing, School of Nursing, Yasuj University of Medical Sciences, Yasuj, Iran
4- Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
2- Department of Nutrition, School of Health and Nutrition, Yasuj University of Medical Sciences, Yasuj, Iran
3- Department of Nursing, School of Nursing, Yasuj University of Medical Sciences, Yasuj, Iran
4- Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
Abstract (557 Views)
Aims: Fatty liver disease is a type of fat accumulation in the liver parenchyma that can be related to lifestyle. Therefore, this study compared the effectiveness of nutrition education with and without physical activity on blood lipids and liver aminotransferase enzymes in men with non-alcoholic fatty liver disease.
Materials & Methods: This study is a randomized clinical trial with a control group, carried out on 80 employees working in the South Pars gas complex in Jam, Iran, suffering from fatty liver. The participants were allocated to four nutrition education groups; a physical activity group, a nutrition education group with physical activity, an education group without physical activity, and a control group (20 people each) using a random block sampling method. In all four groups, 48 hours before the intervention, 3 and 6 months after the intervention, blood lipids and liver enzymes were measured and recorded in a form. Data were analyzed using SPSS 21 software and chi-score statistics, one-way ANOVA, and repeated measures ANOVA test.
Findings: Alanine aminotransferase enzyme showed a significant improvement in each of the 3 intervention groups compared to the control group at 3 and 6 months after the research intervention (p=0.001). Low-density lipoprotein showed a significant improvement in 6 months, which was related to the group of physical activity combined with nutrition education (p=0.005).
Conclusion: Exercise and education interventions are more effective over a longer period of time in preventing and treating non-alcoholic fatty liver disease.
Materials & Methods: This study is a randomized clinical trial with a control group, carried out on 80 employees working in the South Pars gas complex in Jam, Iran, suffering from fatty liver. The participants were allocated to four nutrition education groups; a physical activity group, a nutrition education group with physical activity, an education group without physical activity, and a control group (20 people each) using a random block sampling method. In all four groups, 48 hours before the intervention, 3 and 6 months after the intervention, blood lipids and liver enzymes were measured and recorded in a form. Data were analyzed using SPSS 21 software and chi-score statistics, one-way ANOVA, and repeated measures ANOVA test.
Findings: Alanine aminotransferase enzyme showed a significant improvement in each of the 3 intervention groups compared to the control group at 3 and 6 months after the research intervention (p=0.001). Low-density lipoprotein showed a significant improvement in 6 months, which was related to the group of physical activity combined with nutrition education (p=0.005).
Conclusion: Exercise and education interventions are more effective over a longer period of time in preventing and treating non-alcoholic fatty liver disease.
Keywords:
References
1. Gelli C, Tarocchi M, Abenavoli L, Di Renzo L, Galli A, De Lorenzo A. Effect of a counseling-supported treatment with the Mediterranean diet and physical activity on the severity of the non-alcoholic fatty liver disease. World J Gastroenterol. 2017;23(17):3150. [Link] [DOI:10.3748/wjg.v23.i17.3150]
2. Perdomo CM, Frühbeck G, Escalada J. Impact of nutritional changes on nonalcoholic fatty liver disease. Nutrients. 2019;11(3):677. [Link] [DOI:10.3390/nu11030677]
3. Chegeni M, Nili S, Darabi M, Gheysvandi E, Zahedi R, Sharifian E, et al. Prevalence of non-alcoholic fatty liver and its related factors in Iran: Systematic review and meta-analysis. J Educ Health Promot. 2023;12(1):356. [Link] [DOI:10.4103/jehp.jehp_1056_22]
4. Namjou Z, Jafari SA, Rezaeian A, Ghayour-Mobarhan M, Nasrfard S. The effect of nutritional education program on micronutrient intake in children with chronic liver disease: A clinical trial. J Educ Health Promot. 2021;10. [Link] [DOI:10.4103/jehp.jehp_855_20]
5. Makri E, Goulas A, Polyzos SA. Epidemiology, pathogenesis, diagnosis and emerging treatment of nonalcoholic fatty liver disease. Arch Med Res. 2021;52(1):25-37. [Link] [DOI:10.1016/j.arcmed.2020.11.010]
6. Fan J-G, Kim S-U, Wong VW-S. New trends on obesity and NAFLD in Asia. J Hepatol. 2017;67(4):862-73. [Link] [DOI:10.1016/j.jhep.2017.06.003]
7. Eslamparast T, Tandon P, Raman M. Dietary composition independent of weight loss in the management of non-alcoholic fatty liver disease. Nutrients. 2017;9(8):800. [Link] [DOI:10.3390/nu9080800]
8. Moghaddasifar I, Lankarani K, Moosazadeh M, Afshari M, Ghaemi A, Aliramezany M, et al. Prevalence of non-alcoholic fatty liver disease and its related factors in Iran. Int J Organ Transplantation Med. 2016;7(3):149-60. [Link]
9. Miele L, Targher G. Understanding the association between developing a fatty liver and subsequent cardio-metabolic complications. Expert Rev Gastroenterol Hepatol. 2015;9(10):1243-5. [Link] [DOI:10.1586/17474124.2015.1074860]
10. Younossi ZM. Non-alcoholic fatty liver disease-a global public health perspective. J Hepatol. 2019;70(3):531-44. [Link] [DOI:10.1016/j.jhep.2018.10.033]
11. Cali AM, Zern TL, Taksali SE, De Oliveira AM, Dufour S, Otvos JD, et al. Intrahepatic fat accumulation and alterations in lipoprotein composition in obese adolescents: A perfect proatherogenic state. Diabetes Care. 2007;30(12):3093-8. [Link] [DOI:10.2337/dc07-1088]
12. Shamsoddini A, Sobhani V, Chehreh MEG, Alavian SM, Zaree A. Effect of aerobic and resistance exercise training on liver enzymes and hepatic fat in Iranian men with nonalcoholic fatty liver disease. Hepat Mon. 2015;15(10). [Link] [DOI:10.5812/hepatmon.31434]
13. Del Ben M, Polimeni L, Baratta F, Pastori D, Loffredo L, Angelico F. Modern approach to the clinical management of non-alcoholic fatty liver disease. World J Gastroenterol. 2014;20(26):8341-50. [Link] [DOI:10.3748/wjg.v20.i26.8341]
14. Xiao J, Guo R, Fung ML, Liong EC, Tipoe GL. Therapeutic approaches to non-alcoholic fatty liver disease: Past achievements and future challenges. Hepatobiliary Pancreat Dis Int. 2013;12(2):125-35. [Link] [DOI:10.1016/S1499-3872(13)60021-1]
15. Mahady SE, George J. Exercise and diet in the management of nonalcoholic fatty liver disease. Metabolism. 2016;65(8):1172-82. [Link] [DOI:10.1016/j.metabol.2015.10.032]
16. Houghton D, Thoma C, Hallsworth K, Cassidy S, Hardy T, Burt AD, et al. Exercise reduces liver lipids and visceral adiposity in patients with nonalcoholic steatohepatitis in a randomized controlled trial. Clin Gastroenterol Hepatol. 2017;15(1):96-102. [Link] [DOI:10.1016/j.cgh.2016.07.031]
17. McCarthy EM, Rinella ME. The role of diet and nutrient composition in nonalcoholic fatty liver disease. J Acad Nutr Dietetics. 2012;112(3):401-9. [Link] [DOI:10.1016/j.jada.2011.10.007]
18. Paknahad Z, Zeraei-Bidgoli H. Metabolic syndrome and nonalcoholic fatty liver disease: Nutritional approach for prevention. J Isfahan Med School. 2013;31(252):1461-80. [Persian] [Link]
19. Katsagoni CN, Georgoulis M, Papatheodoridis GV, Panagiotakos DB, Kontogianni MD. Effects of lifestyle interventions on clinical characteristics of patients with non-alcoholic fatty liver disease: A meta-analysis. Metabolism. 2017;68:119-32. [Link] [DOI:10.1016/j.metabol.2016.12.006]
20. Hosseini Kakhk A, Khalegh Zadeh H, Nematy M, Hamedi Nia M. The effect of combined aerobic-resistance training on lipid profile and liver enzymes in patients with non-alcoholic fatty liver under nutrition diet. Sport Physiol. 2015;7(27):65-84. [Persian] [Link]
21. Barani F, Afzalpour ME, Ilbeigi S, Kazemi T, Mohammadifard M. The effect of resistance and combined exercise on serum levels of liver enzymes and fitness indicators in women with nonalcoholic fatty liver disease. 2014;21(2):188-202. [Persian] [Link]
22. Nikroo H, Nematy M, Sima H, AttarzadeHosseini S, Pezeshki M, Esmaeilzadeh A, et al. Therapeutic effects of aerobic exercise and low-calorie diet on nonalcoholic steatohepatitis. Govaresh. 2013;17(4):245-53. [Persian] [Link]
23. Chaudhary S, Kang MK, Sandhu JS. The effects of aerobic versus resistance training on cardiovascular fitness in obese sedentary females. Asian J Sports Med. 2010;1(4):177. [Link] [DOI:10.5812/asjsm.34835]
24. Behzadimoghadam M, Galedari M, Motalebi L. The effect of eight weeks resistance training and low-calorie diet on plasma levels of liver enzymes and liver fat in Non-Alcoholic Fatty Liver Disease±NAFLD). Iran J Nutr Sci Food Technol. 2018;12(4):25-32. [Link]
25. Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, et al. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut. 2011:60(9):1278-83. [Link] [DOI:10.1136/gut.2011.242073]
26. Hasani A, Ansari R, Mazani A. Effect of 8 weeks of aerobic training and using chicory extractive supplementation on serum levels of ALT and AST enzymes in women with fatty liver. Iran J Obstet Gynecol Infertility. 2016;19(10):1-8. [Persian] [Link]
27. Skrypnik D, Ratajczak M, Karolkiewicz J, Mądry E, Pupek-Musialik D, Hansdorfer-Korzon R, et al. Effects of endurance and endurance-strength exercise on biochemical parameters of liver function in women with abdominal obesity. Biomed Pharmacother. 2016;80:1-7. [Link] [DOI:10.1016/j.biopha.2016.02.017]
28. Centis E, Moscatiello S, Bugianesi E, Bellentani S, Fracanzani AL, Calugi S, et al. Stage of change and motivation to healthier lifestyle in non-alcoholic fatty liver disease. J Hepatol. 2013;58(4):771-7. [Link] [DOI:10.1016/j.jhep.2012.11.031]
29. Monserrat-Mesquida M, Quetglas-Llabrés M, Bouzas C, Montemayor S, Mascaró CM, Casares M, et al. A Greater Improvement of intrahepatic fat contents after 6 months of lifestyle intervention is related to a better oxidative stress and inflammatory status in non-alcoholic fatty liver disease. Antioxidants. 2022;11(7):1266. [Link] [DOI:10.3390/antiox11071266]
30. Ghorbanian B, Kordi MR, Ravasi AA, Hedayati M, Ghasemnian AA. The effects of eight weeks interval endurance training on lymphocyte ABCA1 protein expression, plasma apolipoprotein ai and lipid profiles in overweight and obese boy adolescents. Int J Endocrinol Metab. 2013;11(2):76-81. [Link] [DOI:10.5812/ijem.8178]
31. Shearman J, Micklewright D, Hardcastle J, Hamlin MJ, Draper N. The effect of physical activity on serum lipids, lipoprotein, and apolipoproteins. Arch Exercise Health Dis. 2010;1(2):43-9. [Link]