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Volume 5, Issue 2 (2024)
J Clinic Care Skill 2024, 5(2): 63-68 |
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Received: 2024/02/20 | Accepted: 2024/05/28 | Published: 2024/06/25
Received: 2024/02/20 | Accepted: 2024/05/28 | Published: 2024/06/25
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Ghorbani A, Kareem Abed E, Ghiyasvandian S, Salami M. Association between Health Literacy and Medication Adherence in Patients with Cirrhosis. J Clinic Care Skill 2024; 5 (2) :63-68
URL: http://jccs.yums.ac.ir/article-1-244-en.html
URL: http://jccs.yums.ac.ir/article-1-244-en.html
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1- Department of Medical-Surgical Nursing, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran
2- Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran
2- Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran
Abstract (830 Views)
Aims: Health literacy is a critical factor in achieving good health, as it plays a central role in health and healthcare. Another important factor affecting health outcomes is medication adherence, especially in patients with chronic liver disease and cirrhosis. Therefore, this study aimed to investigate the association between health literacy and medication adherence in patients with cirrhosis.
Instruments & Methods: This was a descriptive study on 141 cirrhosis patients from two teaching hospitals in Iraq between December 2022 and April 2023, recruited using a convenience sampling method. Data collection was carried out using three self-report questionnaires, including demographic characteristics, the All Aspects of Health Literacy Scale, and the Adherence to Refills and Medications Scale. Data analysis was performed using SPSS software version 16.
Findings: Most patients (92.90%) exhibited non-adherence to medication, with a medication adherence score of more than 16. Additionally, 75.88% of patients demonstrated a low level of health literacy. A positive and significant correlation was observed between medication adherence and total health literacy score (r=0.358, p<0.001).
Conclusion: The majority of patients exhibit low health literacy and non-adherence to medications.
Instruments & Methods: This was a descriptive study on 141 cirrhosis patients from two teaching hospitals in Iraq between December 2022 and April 2023, recruited using a convenience sampling method. Data collection was carried out using three self-report questionnaires, including demographic characteristics, the All Aspects of Health Literacy Scale, and the Adherence to Refills and Medications Scale. Data analysis was performed using SPSS software version 16.
Findings: Most patients (92.90%) exhibited non-adherence to medication, with a medication adherence score of more than 16. Additionally, 75.88% of patients demonstrated a low level of health literacy. A positive and significant correlation was observed between medication adherence and total health literacy score (r=0.358, p<0.001).
Conclusion: The majority of patients exhibit low health literacy and non-adherence to medications.
Keywords:
References
1. Zhao L, Chen S, Shi X, Cao H, Li L. A pooled analysis of mesenchymal stem cell-based therapy for liver disease. Stem Cell Res Ther. 2018;9(1):72. [Link] [DOI:10.1186/s13287-018-0816-2]
2. Kurokawa T, Ohkohchi N. Role of platelet, blood stem cell, and thrombopoietin in liver regeneration, liver cirrhosis, and liver diseases. In: Stem cells and cancer in hepatology: From the essentials to application. Cambridge: Academic Press; 2018. p. 159-77. [Link] [DOI:10.1016/B978-0-12-812301-0.00009-8]
3. Mujica-Mota RE, Roberts M, Abel G, Elliott M, Lyratzopoulos G, Roland M, et al. Common patterns of morbidity and multi-morbidity and their impact on health-related quality of life: Evidence from a national survey. Qual Life Res. 2015;24(4):909-18. [Link] [DOI:10.1007/s11136-014-0820-7]
4. Fernandez-Lazaro CI, García-González JM, Adams DP, Fernandez-Lazaro D, Mielgo-Ayuso J, Caballero-Garcia A, et al. Adherence to treatment and related factors among patients with chronic conditions in primary care: A cross-sectional study. BMC Fam Pract. 2019;20(1):132. [Link] [DOI:10.1186/s12875-019-1019-3]
5. Rademakers J, Heijmans M. Beyond reading and understanding: Health literacy as the capacity to act. Int J Environ Res Public Health. 2018;15(8):1676. [Link] [DOI:10.3390/ijerph15081676]
6. Nguyen MP, Amoon AT, Lee L, Chiang V, Sun AQ, Ji M, et al. Health literacy, knowledge, and risk factors for fatty liver disease among Asian American and Pacific Islanders and Latinos in Los Angeles. Asian Pac J Cancer Prev. 2021;22(6):1737-44. [Link] [DOI:10.31557/APJCP.2021.22.6.1737]
7. Ghisi GLM, Chaves GSDS, Britto RR, Oh P. Health literacy and coronary artery disease: A systematic review. Patient Educ Couns. 2018;101(2):177-84. [Link] [DOI:10.1016/j.pec.2017.09.002]
8. Neter E, Brainin E. Association between health literacy, eHealth literacy, and health outcomes among patients with long-term conditions: A systematic review. Eur Psychol. 2019;24(1):68-81. [Link] [DOI:10.1027/1016-9040/a000350]
9. Salem OA, Sulami A, Al-Ammar KA. Evaluation of health literacy among females in outpatient clinics. Ann Med Health Sci Res. 2018;8(1):100-4. [Link]
10. Taylor DM, Fraser S, Dudley C, Oniscu GC, Tomson C, Ravanan R, et al. Health literacy and patient outcomes in chronic kidney disease: A systematic review. Nephrol Dial Transplant. 2018;33(9):1545-58. [Link] [DOI:10.1093/ndt/gfx293]
11. Rajah R, Hassali MAA, Murugiah MK. A systematic review of the prevalence of limited health literacy in Southeast Asian countries. Public Health. 2019;167:8-15. [Link] [DOI:10.1016/j.puhe.2018.09.028]
12. Hoffman S, Marsiglia FF, Nevarez L, Porta M. Health literacy among youth in Guatemala City. Soc Work Public Health. 2017;32(1):30-7. [Link] [DOI:10.1080/19371918.2016.1188741]
13. Shiha G, Korenjak M, Eskridge W, Casanovas T, Velez-Moller P, Högström S, et al. Redefining fatty liver disease: An international patient perspective. Lancet Gastroenterol Hepatol. 2021;6(1):73-9. [Link] [DOI:10.1016/S2468-1253(20)30294-6]
14. Rowlands G, Shaw A, Jaswal S, Smith S, Harpham T. Health literacy and the social determinants of health: A qualitative model from adult learners. Health Promot Int. 2017;32(1):130-8. [Link]
15. Martinez C. Implementation of a medication adherence protocol in a large urban safety net hospital. New Haven: Yale School of Nursing Digital Theses; 2022. [Link]
16. Unni EJ. Medication adherence. In: Encyclopedia of pharmacy practice and clinical pharmacy. Amsterdam: Elsevier; 2019. p. 27-37. [Link]
17. Al-Haj Mohd MMM, Phung H, Sun J, Morisky DE. Improving adherence to medication in adults with diabetes in the United Arab Emirates. BMC Public Health. 2016;16(1):857. [Link] [DOI:10.1186/s12889-016-3492-0]
18. Milosavljevic A, Aspden T, Harrison J. Community pharmacist-led interventions and their impact on patients' medication adherence and other health outcomes: A systematic review. Int J Pharm Pract. 2018;26(5):387-97. [Link] [DOI:10.1111/ijpp.12462]
19. Polis S, Zang L, Mainali B, Pons R, Pavendranathan G, Zekry A, et al. Factors associated with medication adherence in patients living with cirrhosis. J Clin Nurs. 2016;25(1-2):204-12. [Link] [DOI:10.1111/jocn.13083]
20. Hayes PC, Davis JM, Lewis JA, Bouchier IA. Meta-analysis of value of propranolol in prevention of variceal haemorrhage. Lancet. 1990;336(8708):153-6. [Link] [DOI:10.1016/0140-6736(90)91668-Z]
21. De Geest S, Zullig LL, Dunbar-Jacob J, Helmy R, Hughes DA, Wilson IB, et al. ESPACOMP Medication Adherence Reporting Guideline (EMERGE). Ann Intern Med. 2018;169(1):30-5. [Link] [DOI:10.7326/M18-0543]
22. Zhang NJ, Terry A, McHorney CA. Impact of health literacy on medication adherence: A systematic review and meta-analysis. Ann Pharmacother. 2014;48(6):741-51. [Link] [DOI:10.1177/1060028014526562]
23. Hyvert S, Yailian AL, Haesebaert J, Vignot E, Chapurlat R, Dussart C, et al. Association between health literacy and medication adherence in chronic diseases: A recent systematic review. Int J Clin Pharm. 2023;45(1):38-51. [Link] [DOI:10.1007/s11096-022-01470-z]
24. Montazer GA, Al-Rikabi YK, editors. Identifying the obstacles of implementing e-learning in Iraqi universities. Proceedings of the 2021 7th International Conference on Web Research (ICWR). Tehran; 2021. [Link] [DOI:10.1109/ICWR51868.2021.9443154]
25. Dore‐Stites D, Lopez MJ, Magee JC, Bucuvalas J, Campbell K, Shieck V, et al. Health literacy and its association with adherence in pediatric liver transplant recipients and their parents. Pediatr Transplant. 2020;24(5):e13726. [Link] [DOI:10.1111/petr.13726]
26. Chinn D, McCarthy C. All Aspects of Health Literacy Scale (AAHLS): Developing a tool to measure functional, communicative and critical health literacy in primary healthcare settings. Patient Educ Couns. 2013;90(2):247-53. [Link] [DOI:10.1016/j.pec.2012.10.019]
27. Siddiqui R. A comprehensive approach to health literacy: Validating the all aspects of health literacy scale in a respresentative sample of Arabic-speaking adult Syrian refugees [MA Thesis]. Canada: McMaster University-Department of Global Health; 2017. [Link]
28. Alammari G, Alhazzani H, AlRajhi N, Sales I, Jamal A, Almigbal TH, et al. Validation of an Arabic Version of the Adherence to Refills and Medications Scale (ARMS). Healthcare. 2021;9(11):1430. [Link] [DOI:10.3390/healthcare9111430]
29. Lomper K, Chabowski M, Chudiak A, Białoszewski A, Dudek K, Jankowska-Polańska B. Psychometric evaluation of the Polish version of the Adherence to Refills and Medications Scale (ARMS) in adults with hypertension. Patient Prefer Adherence. 2018;12:2661-70. [Link] [DOI:10.2147/PPA.S185305]
30. Mitra D, Davis KL, Beam C, Medjedovic J, Rustgi V. Treatment patterns and adherence among patients with chronic hepatitis C virus in a US managed care population. Value Health. 2010;13(4):479-86. [Link] [DOI:10.1111/j.1524-4733.2009.00691.x]
31. Xu K, Liu LM, Farazi PA, Wang H, Rochling FA, Watanabe-Galloway S, et al. Adherence and perceived barriers to oral antiviral therapy for chronic hepatitis B. Glob Health Action. 2018;11(1):1433987. [Link] [DOI:10.1080/16549716.2018.1433987]
32. Rahmati M, Rejeh N, Heravi Karimooi M, Tadrisi SD. Investigating the relationship between health literacy and adherence with treatment regimen in the elderly with hypertension. Iran J Nurs Res. 2019;13(5):15-22. [Persian] [Link]
33. Kugler C, Vlaminck H, Haverich A, Maes B. Nonadherence with diet and fluid restrictions among adults having hemodialysis. J Nurs Scholarsh. 2005;37(1):25-9. [Link] [DOI:10.1111/j.1547-5069.2005.00009.x]
34. Kamezaki H, Kanda T, Arai M, Wu S, Nakamoto S, Chiba T, et al. Adherence to medication is a more important contributor to viral breakthrough in chronic hepatitis B patients treated with entecavir than in those with lamivudine. Int J Med Sci. 2013;10(5):567-74. [Link] [DOI:10.7150/ijms.5795]
35. Kooshyar H, Shoorvazi M, Dalir Z, Hosseini M. Health literacy and its relationship with medical adherence and health-related quality of life in diabetic community-residing elderly. J Mazandaran Univ Med Sci. 2013;22(1):134-43. [Persian] [Link]
36. Reisi M, Mostafavi F, Hasanzade A, Sharifirad GR. The relationship between health literacy, health status and healthy behaviors among elderly in Isfahan, Iran. J Health Syst Res. 2011;7(4). [Persian] [Link]
37. Goldsworthy MA, Fateen W, Thygesen H, Aldersley MA, Rowe IA, Jones RL. Patient understanding of liver cirrhosis and improvement using multimedia education. Frontline Gastroenterol. 2017;8(3):214-9. [Link] [DOI:10.1136/flgastro-2016-100761]
38. Burnham B, Wallington S, Jillson IA, Trandafili H, Shetty K, Wang J, et al. Knowledge, attitudes, and beliefs of patients with chronic liver disease. Am J Health Behav. 2014;38(5):737-44. [Link] [DOI:10.5993/AJHB.38.5.11]
39. Majid B, Khan R, Junaid Z, Khurshid O, Rehman SH, Jaffri SN, et al. Assessment of knowledge about the risk factors of chronic liver disease in patients admitted in civil hospital Karachi. Cureus. 2019;11(10):e5945. [Link] [DOI:10.7759/cureus.5945]
40. Lee YM, Yu HY, You MA, Son YJ. Impact of health literacy on medication adherence in older people with chronic diseases. Collegian. 2017;24(1):11-8. [Link] [DOI:10.1016/j.colegn.2015.08.003]
41. Lor M, Koleck TA, Bakken S, Yoon S, Dunn Navarra AM. Association between health literacy and medication adherence among Hispanics with hypertension. J Racial Ethn Health Disparities. 2019;6(3):517-24. [Link] [DOI:10.1007/s40615-018-00550-z]
42. Suhail M, Saeed H, Saleem Z, Younas S, Hashmi FK, Rasool F, et al. Association of health literacy and medication adherence with health-related quality of life (HRQoL) in patients with ischemic heart disease. Health Qual Life Outcomes. 2021;19(1):118. [Link] [DOI:10.1186/s12955-021-01761-5]
43. Qobadi M, Besharat MA, Rostami R, Rahiminezhad A. Health literacy and medical adherence in hemodialysis patients: The mediating role of disease-specific knowledge. Thrita J Neu. 2015;4(1):e26195. [Link] [DOI:10.5812/thrita.26195]