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Volume 7, Issue 1 (2026)
J Clinic Care Skill 2026, 7(1): 15-20 |
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Received: 2025/11/22 | Accepted: 2025/12/28 | Published: 2026/01/15
Received: 2025/11/22 | Accepted: 2025/12/28 | Published: 2026/01/15
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Mohammadhoseini A, Momtahan E, Mansourian A. Propofol vs. Dexmedetomidine Sedation in Post-Cholecystectomy Patients. J Clinic Care Skill 2026; 7 (1) :15-20
URL: http://jccs.yums.ac.ir/article-1-464-en.html
URL: http://jccs.yums.ac.ir/article-1-464-en.html
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1- “Department of Anesthesiology, Faculty of Medicine” and “Clinical Research Development Unit Shahid Jalil”, Yasuj University of Medical Science, Yasuj, Iran
2- Student Research Committee, Yasuj University of Medical Science, Yasuj, Iran
2- Student Research Committee, Yasuj University of Medical Science, Yasuj, Iran
Abstract (766 Views)
Aims: Propofol and dexmedetomidine are used for general anesthesia. This study aimed to compare the effects of propofol and dexmedetomidine infusion on sedation in the recovery room for patients undergoing cholecystectomy.
Materials & Methods: This randomized clinical trial was conducted on 70 patients scheduled for laparoscopic cholecystectomy in Yasuj between 2023 and 2024. Patients were randomly assigned to two groups, including 35 cases who received propofol and 35 cases who received dexmedetomidine. The level of agitation was assessed using the Richmond Agitation-Sedation Scale at 0 and 40 minutes after surgery by the researcher. Data analysis was performed using SPSS 27 software utilizing the Chi-square test, independent t-test, and paired t-test. A significance level of p<0.05 was considered.
Findings: At 40 minutes after the intervention, the mean agitation level in patients receiving dexmedetomidine (0.22±0.72) was significantly lower than that of the propofol group (0.63±0.81), indicating better sedation (p=0.028).
Conclusion: Dexmedetomidine is a preferable option than propofol for anesthesia management in patients undergoing laparoscopic cholecystectomy.
Materials & Methods: This randomized clinical trial was conducted on 70 patients scheduled for laparoscopic cholecystectomy in Yasuj between 2023 and 2024. Patients were randomly assigned to two groups, including 35 cases who received propofol and 35 cases who received dexmedetomidine. The level of agitation was assessed using the Richmond Agitation-Sedation Scale at 0 and 40 minutes after surgery by the researcher. Data analysis was performed using SPSS 27 software utilizing the Chi-square test, independent t-test, and paired t-test. A significance level of p<0.05 was considered.
Findings: At 40 minutes after the intervention, the mean agitation level in patients receiving dexmedetomidine (0.22±0.72) was significantly lower than that of the propofol group (0.63±0.81), indicating better sedation (p=0.028).
Conclusion: Dexmedetomidine is a preferable option than propofol for anesthesia management in patients undergoing laparoscopic cholecystectomy.
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