IMEMR
66.92
Volume 1, Issue 4 (2020)                   J Clinic Care Skill 2020, 1(4): 165-170 | Back to browse issues page
Article Type:
Original Research |

Print XML PDF HTML


History

How to cite this article
Hekmatzadeh S, Aramesh S, Baashti S. Comparing the Effect of Boiled Anethum graveolens Seed with Oxytocin on the Duration of Labor and Pain in Iranian Women: A Randomized Clinical Trial. J Clinic Care Skill 2020; 1 (4) :165-170
URL: http://jccs.yums.ac.ir/article-1-73-en.html
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rights and permissions
1- Medicinal Plant Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
2- Gynecology & Obstetrics Department, Yasuj University of Medical Sciences, Yasuj, Iran
* Corresponding Author Address: Yasuj University of Medical Sciences, Yasuj, Iran. (sf.hekmatzadeh@yahoo.com)
Abstract   (1620 Views)
Aim(s): To advance birth and avoid prolonged labor, oxytocin is routinely used globally. However there are a number of side-effects in this therapy. The aim of this study was to evaluate the effect of boiled Anethum graveolens seed on the duration and intensity of labor pain in comparison to oxytocin.
Materials & Methods: This randomized clinical trial was conducted on 88 pregnant women admitted to the birth center of Imam Sajjad, Yasuj hospital, Iran in 2015-2016. The subjects were selected by purposive sampling method and randomly allocated to Anethum graveolens (n=41) and oxytocin (n=47) groups. In Anethum graveolens group, 10gr of Anethum graveolens seed was boiled in 100ml of water for 10 minutes and, after filtration, was given to participants to swallow at the start of active labor. In oxytocin group, 10 units of oxytocin in 1000ml of Ringer’s solution was diluted and administered by infusion when the contractions were established. Data were analyzed by SPSS 21 software using chi square, Mann-Whitney U and independent t test.
Findings: Labor was shorter in the first, second and third stages in Anethum graveolens group compared to oxytocin group. However there was a significant difference only in the 1st stage of labor (p<0.001). The dilatation and effacement scores improved in Anethum graveolens group than the oxytocin group (p<0.05) at one, two, three, and four hours of continuous intervention.
Conclusion: Using boiled Anethum graveolens seed can be effective in reducing the length of labor and improving dilatation and effacement during birth.
Keywords:

References
1. Hekmatzadeh SF, Mirmolaei ST, Hosseini N. The effect of boiled dill (Anethum graveolens) seeds on the long active phase and labor pain intensity. Armaghan-e-Danesh. 2012;17(1):50-9. [Persian] [link]
2. Zhang J, Klebanoff MA, DerSimonian R. Epidural analgesia in association with duration of labor and mode of delivery: a quantitative review. Am J Obstet Gynecol. 1999;180(4):970-7. [link] [DOI:10.1016/S0002-9378(99)70669-1]
3. Cheng YW, Hopkins LM, Caughey AB. How long is too long: Does a prolonged second stage of labor in nulliparous women affect maternal and neonatal outcomes? Am J Obstet Gynecol. 2004;191(3):933-8. [link] [DOI:10.1016/j.ajog.2004.05.044] [PMID]
4. Cheng YW, Hopkins LM, Laros RK, Jr., Caughey AB. Duration of the second stage of labor in multiparous women: maternal and neonatal outcomes. Am J Obstet Gynecol. 2007;196(6):585.e1-6. [link] [DOI:10.1016/j.ajog.2007.03.021] [PMID]
5. Parashi S, Kashanian M, Bazzaz Banaei N. Comparison between two oxytocin regimen for induction of labor. Feyz. 2005;9(2):6-10. [Persian] [link]
6. Wortsman J, de Angeles S, Futterweit W, Singh KB, Kaufmann RC. Gestational diabetes and neonatal macrosomia in the polycystic ovary syndrome. J Reprod Med. 1991;36(9):659-61. [link]
7. Ebrahimzadeh Zagami S, Golmakani N, Kabirian M, Shakeri MT. Effect of dill (Anethum graveolens Linn.) seed on uterus contractions pattern in active phase of labor. Indian J Trad Knowledge. 2012;11(4):602-6. [link]
8. Orief YI, Farghaly NF, Ibrahim MIA. Use of herbal medicines among pregnant women attending family health centers in Alexandria. Middle East Fertil Soc J. 2014;19(1):42-50. [link] [DOI:10.1016/j.mefs.2012.02.007]
9. Ishikawa T, Kudo M, Kitajima J. Water-soluble constituents of dill. Chem Pharm Bull. 2002;50(4):501-7. [link] [DOI:10.1248/cpb.50.501] [PMID]
10. Lis-Balchin M, Hart S. A preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro. J Ethnopharmacol. 1997;58(3):183-7. [link] [DOI:10.1016/S0378-8741(97)00103-7]
11. Hekmatzadeh SF, Bazarganipour F, Malekzadeh J, Goodarzi F, Aramesh S. A randomized clinical trial of the efficacy of applying a simple protocol of boiled Anethum Graveolens seeds on pain intensity and duration of labor stages. Complement Ther Med. 2014;22(6):970-6. [link] [DOI:10.1016/j.ctim.2014.10.007] [PMID]
12. Mahdavian M, Golmakani N, Mansoori A, Hosseinzadeh H, Afzalaghaei M. An investigation of effectiveness of oral dill extracts on postpartum hemorrhage. Iran J Obstet Gynecol Infertil. 2001;4(7-8):19-26. [Persian] [link]
13. Koren G, Boskovic R, Hard M, Maltepe C, Navioz Y, Einarson A. Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy. Am J Obstet Gynecol. 2002;186(5 Suppl Understanding):S228-31. [link] [DOI:10.1067/mob.2002.123054] [PMID]
14. Donyavi T, Naieni KH, Nedjat S, Vahdaninia M, Najafi M, Montazeri A. Socioeconomic status and mortality after acute myocardial infarction: a study from Iran. Int J Equity Health. 2011;10:9. [link] [DOI:10.1186/1475-9276-10-9] [PMID] [PMCID]
15. Owen J, Szychowski JM, Hankins G, Iams JD, Sheffield JS, Perez-Delboy A, et al. Does Mid-trimester Cervical Length ≥25 mm Predict Preterm Birth in High-Risk Women? Am J Obstet Gynecol. 2010;203(4):393.e1-5. [link] [DOI:10.1016/j.ajog.2010.06.025] [PMID] [PMCID]
16. Chang WY, Knochenhauer ES, Bartolucci AA, Azziz R. Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups. Fertil Steril. 2005;83(6):1717-23. [link] [DOI:10.1016/j.fertnstert.2005.01.096] [PMID]
17. Taghavi SA, Bazarganipour F, Allan H, Khashavi Z, Reisi N, Dosha N, et al. Pelvic floor dysfunction and polycystic ovary syndrome. Hum Fertil. 2017;20(4):262-7. [link] [DOI:10.1080/14647273.2017.1292003] [PMID]
18. Goldman AS, Thorpe LW, Goldblum RM, Hanson LA. Anti-inflammatory properties of human milk. Acta Paediatr Scand. 1986;75(5):689-95. [link] [DOI:10.1111/j.1651-2227.1986.tb10275.x] [PMID]
19. Hatami H, Seyednozadi M, Razavi SM, Majlesi F, Parizade SMJ, Eftekhar Ardabili H. Textbook of public health‏. Volume 3. Tehran: Arjmand; 2006. [Persian] [link]
20. Committee for Veterinary Medicinal Products. Juniperi fructus is the dried berry-like cones of Juniperus communis. London: The European Agency for the Evaluation of Medicinal Products; 1999 Mar. Report No. EMEA/MRL/562-99-FINAL. [link]
21. Mansouri M, Nayebi N, Keshtkar A, Hasani-Ranjbar S, Taheri E, Larijani B. The effect of 12 weeks Anethum graveolens (dill) on metabolic markers in patients with metabolic syndrome; a randomized double blind controlled trial. Daru. 2012;20(1):47. [link] [DOI:10.1186/2008-2231-20-47] [PMID] [PMCID]
22. Vankrieken L. Testosterone and the free androgen index. Los Angeles, CA: Diagnostic Products Corporation; 1997. [link]