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Volume 2, Issue 1 (2021)
J Clinic Care Skill 2021, 2(1): 41-43 |
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Received: 2020/05/20 | Accepted: 2020/08/28 | Published: 2021/01/20
Received: 2020/05/20 | Accepted: 2020/08/28 | Published: 2021/01/20
How to cite this article
Daneshyar Z, Shokripour M. Fibroepithelial Stromal Polyp as Low Back Lesion in 88-year-old Man: a Case Report. J Clinic Care Skill 2021; 2 (1) :41-43
URL: http://jccs.yums.ac.ir/article-1-89-en.html
URL: http://jccs.yums.ac.ir/article-1-89-en.html
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Authors
Z. Daneshyar *1, M. Shokripour2
1- Clinical Research Development Unit, Yasuj University of Medical Sciences, Yasuj, Iran
2- Department of Pathology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
2- Department of Pathology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract (2247 Views)
Introduction: Fibroepithelial stromal polyp (FESP) of the female lower genital tract is a rare benign lesion characterized by polypoid proliferation of stroma, covered by a benign squamous epithelium in the vulvovaginal region. These hormone-sensitive lesions usually occur in young to middle-aged women. The lesions are typically no larger than 5 cm in diameter and are found randomly during routine gynecologic examinations.
Patient Information: The case of this study was an 88-year-old man with a solitary polypoid lesion measuring 3×2×2 in the low back area showing the histological appearances of those described in the vulvovaginal region.
It was a well-circumscribed gray-brown lesion covered by wrinkled skin. Histopathological examination revealed edematous hypocellular lesion at low magnification with hyperplastic squamous epithelium coating with reactive epithelial change. At high magnification, the lesion consisted of bland-appearing spindle and stellate-shaped cells in an edematous and fibrous stroma with a large number of variably-sized blood vessels. Immunohistochemistry showed the lesional cells to be focally immunoreactive for EMA and negative for CD34, SMA in stromal cells.
Conclusion: FESPs is an uncommon benign lesion that can occur in men and areas other than the genitals with independence from female sex hormones. Although this is a benign finding, reporting it will increase the knowledge about this rare tumor.
Patient Information: The case of this study was an 88-year-old man with a solitary polypoid lesion measuring 3×2×2 in the low back area showing the histological appearances of those described in the vulvovaginal region.
It was a well-circumscribed gray-brown lesion covered by wrinkled skin. Histopathological examination revealed edematous hypocellular lesion at low magnification with hyperplastic squamous epithelium coating with reactive epithelial change. At high magnification, the lesion consisted of bland-appearing spindle and stellate-shaped cells in an edematous and fibrous stroma with a large number of variably-sized blood vessels. Immunohistochemistry showed the lesional cells to be focally immunoreactive for EMA and negative for CD34, SMA in stromal cells.
Conclusion: FESPs is an uncommon benign lesion that can occur in men and areas other than the genitals with independence from female sex hormones. Although this is a benign finding, reporting it will increase the knowledge about this rare tumor.
References
1. Yoo J, Je BK, Yeom SK, Park YS, Min KJ, Lee JH. Giant fibroepithelial stromal polyp of the vulva: Diffusion-weighted and conventional magnetic resonance imaging features and pathologic correlation. J Pediatr Adolesc Gynecol. 2019;32(1):93-7. [DOI:10.1016/j.jpag.2018.08.006] [PMID]
2. Halvorsen TB, Johannesen E. Fibroepithelial polyps of the vagina: Are they old granulation tissue polyps?. J Clin Pathol. 1992;45(3):235-40. [DOI:10.1136/jcp.45.3.235] [PMID] [PMCID]
3. Bozgeyik Z, Kocakoc E, Koc M, Ferda Dagli A. Giant fibroepithelial stromal polyp of the vulva: Extended field‐of‐view ultrasound and computed tomographic findings. Ultrasound Obstet Gynecol. 2007;30(5):791-2. [DOI:10.1002/uog.5143] [PMID]
4. Zulfikaroglu E, Kilic S, Taflan S, Tarhan I, Akbay S, Mollamahmutoglu L. Vulvar fibroepithelial stromal polyp in the early pregnancy. Van Tip Dergisil. 2013;20(2):88-90. [Turkish]
5. Shaaban AM, Turton EP, Merchant W. An unusual case of a large fibroepithelial stromal polyp presenting as a nipple mass. BMC Res Notes. 2013;6:345. [DOI:10.1186/1756-0500-6-345] [PMID] [PMCID]
6. Lee MH, Hwang JY, Lee JH, Kim DH, Song SH. Fibroepithelial polyp of the vulva accompanied by lymphangioma circumscriptum. Obstet Gynecol Sci. 2017;60(4):401-4. [DOI:10.5468/ogs.2017.60.4.401] [PMID] [PMCID]
7. Rexhepi M, Trajkovska E, Besimi F, Rufati N. Giant fibroepithelial polyp of vulva: A case report and review of literature. Prilozi. 2018;39(2-3):127-30. [DOI:10.2478/prilozi-2018-0051] [PMID]
8. Madueke-Laveaux OS, Gogoi R, Stoner G. Giant fibroepithelial stromal polyp of the vulva: Largest case reported. Ann Surg Innov Res. 2013;7:8. [DOI:10.1186/1750-1164-7-8] [PMID] [PMCID]
9. Arora BK. A clinical case of large fibroepithelial polyp of breast nipple. Int J Case Rep Images. 2019;10:100997Z01BA2019. [DOI:10.5348/100997Z01BA2019CR]
10. Hasan M, Afrose R, Kamal M. Cellular pseudosarcomatous fibroepithelial stromal polyp of the cervix: A lesion mimicking as sarcoma. Adv Cytol Pathol. 2018;3(1):21-3. [DOI:10.15406/acp.2018.03.00046]
11. Elwood HR. Skin nonmelanocytic tumor fibrous, fibrohistiocytic and myofibroblastic neoplasms fibroepithelial polyp [Internet]. Detroit: Pathology Outlines; 2015 [Cited 2020 9 29]. Available from: https://www.pathologyoutlines.com/topic/skintumornonmelanocyticfibroepithelialpolyp.html.