IMEMR
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66.92
Index Copernicus
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About Journal of Clinical Care and Skills
Journal of Clinical Care and Skills (JCCS) is a quarterly peer-reviewed online journal that has been published by the Afarand Scholarly Publishing Institute in Iran since Winter 2020. It was established in 2018, at the Hazrat-e Zeynab Faculty of Nursing, affiliated with Yasuj University of Medical Sciences, Iran. The JCCS's main objective is to publish researches on the health of Iranian people. The mission of JCCS is to help promote studies in health sciences and educate experts and specialists in health centers across Iran as well as other countries.
Announcements
- Publication fees: all articles that submitted from September 22, 2024, will be charged for publication fees.
- JCCS has been accepted by the Iranian Commission for Medical Journals (Letter).
Announcements
- Publication fees: all articles that submitted from September 22, 2024, will be charged for publication fees.
- JCCS has been accepted by the Iranian Commission for Medical Journals (Letter).
12.3 days
Submission to First Review
61 days
Submission to Accept
17.5 days
Accept to Publish
38.91 %
Acceptance Rate
Editor-in-Chief
Nazafarin Hosseini; PhD
Professor of Nursing; Yasuj University of Medical Sciences, Yasuj, Iran
Scientific Supporters
Yasuj University of Medical Sciences
Articles
The Role of Digital Technologies in Self-Management of Chronic Diseases; Challenges and Opportunities
A. Marzban
This article has no abstract.
View Abstract
The relationship between the experience of the second victim phenomenon and the quality of professional life and silence about patient safety among nurses working in educational and medical centers
Jaafar Kooshki, amir sadeghi, Zahra Bakhtiari, Leili Tapak
Introduction: When adverse events due to nursing errors occur, nurses are affected as second victims. This study aimed to investigate the consequences and experiences of the second victim phenomenon in nurses and its relationship with the components of professional quality of life and silence about patient safety.
Methods: This is a descriptive-analytical correlational study that was conducted using a stratified-proportional random sampling method on 232 nurses working in healthcare centers of Lorestan University of Medical Sciences in 1402. To collect data, the Second Victim Experience Questionnaire, the Stam Professional Quality of Life Questionnaire, Fifth Edition, Patient Safety Silence, and the Demographic Information Checklist were used. The data were analyzed using SPSS version 26.
Findings: The mean score of the second victim experience among the participants was 114.38 with a standard deviation of 11.05 points. Most of the participants in the present study (94.4%) were at an average level in terms of second victim experience. There is a negative and statistically significant relationship between the experience of the second victim phenomenon and quality of life (p >0.001, r = -0.366). There was no statistically significant linear relationship between the experience of the second victim and patient safety silence (P < 0.05).
Conclusion: This study shows that the experience of the second victim phenomenon has negative effects on quality of life and some related factors, and the importance of addressing the working and psychological conditions of nurses to improve their quality of life is clear.
Methods: This is a descriptive-analytical correlational study that was conducted using a stratified-proportional random sampling method on 232 nurses working in healthcare centers of Lorestan University of Medical Sciences in 1402. To collect data, the Second Victim Experience Questionnaire, the Stam Professional Quality of Life Questionnaire, Fifth Edition, Patient Safety Silence, and the Demographic Information Checklist were used. The data were analyzed using SPSS version 26.
Findings: The mean score of the second victim experience among the participants was 114.38 with a standard deviation of 11.05 points. Most of the participants in the present study (94.4%) were at an average level in terms of second victim experience. There is a negative and statistically significant relationship between the experience of the second victim phenomenon and quality of life (p >0.001, r = -0.366). There was no statistically significant linear relationship between the experience of the second victim and patient safety silence (P < 0.05).
Conclusion: This study shows that the experience of the second victim phenomenon has negative effects on quality of life and some related factors, and the importance of addressing the working and psychological conditions of nurses to improve their quality of life is clear.
The Effect of Deracocephalum Kotschyi Boiss or Melisa Officinalis on Depression in Patients with Depression
Z. Hashemiئohammadabad, M. Hashemimohammadabad, I. Yazdanpanah, D. Razmjoue, F. Karimi, N. Hashemimohammadabad
Materials & Methods This study was a quasi-experimental study with pre-test and post-test phases with 39 patients in 2023. In the control group, escitalopram (10 mg daily, single tablet) was prescribed for 30 days, and in the intervention group escitalopram (10 mg daily, single tablet) and melissa officinalis hydrochloride capsules (500 mg daily, single tablet) were prescribed for 30 days. Depression was measured by the Hamilton Depression Rating Scale and the Beck Depression Inventory. For the analysis of the data, chi-square test, paired t-tests and independent t-tests with significance of 0.05, SPSS version 26 were used.
Findings Seventy-eight participants were divided into two groups of 39. Regarding demographic variables, there was no statistically significant difference in treatment rates between the intervention and control groups. There was no significant difference between the two groups in severity of depression as measured by the Beck and Hamilton scales in pre-test (p=0.533, p=0.570). The severity of depression on the depression scale decreased significantly (p<0.001) in both groups in post-test, but the severity of depression on both scales decreased significantly (p<0.001) in the intervention group after intervention.
Conclusion Melisa Officinalis extract may be effective in reducing symptoms of depression when used in combination with the medicine escitalopram. However, to confirm this finding and to establish lemon balm as a new treatment option, larger, longer term clinical studies are needed to investigate the potential side effects and the exact mechanism of action of the product.
View Abstract
Findings Seventy-eight participants were divided into two groups of 39. Regarding demographic variables, there was no statistically significant difference in treatment rates between the intervention and control groups. There was no significant difference between the two groups in severity of depression as measured by the Beck and Hamilton scales in pre-test (p=0.533, p=0.570). The severity of depression on the depression scale decreased significantly (p<0.001) in both groups in post-test, but the severity of depression on both scales decreased significantly (p<0.001) in the intervention group after intervention.
Conclusion Melisa Officinalis extract may be effective in reducing symptoms of depression when used in combination with the medicine escitalopram. However, to confirm this finding and to establish lemon balm as a new treatment option, larger, longer term clinical studies are needed to investigate the potential side effects and the exact mechanism of action of the product.
Death anxiety and related factors in CABG candidate patients
G. Rezaei, F. Salmani
Aims: Coronary artery bypass grafting (CABG) is a recommended and effective treatment for some heart patients. Among its psychological complications, death anxiety is one of the most common. Various factors can influence the development and severity of this anxiety. This study aimed to investigate death anxiety and its related factors in patients scheduled for CABG.
Methods: This descriptive-correlational study was conducted in 2024 at Shariati Hospital in Isfahan. A total of 100 CABG candidates admitted to the cardiac intensive care unit were selected via convenience sampling. After obtaining informed consent, participants were instructed on completing a questionnaire, which consisted of three parts: demographic data and Templer's Death Anxiety Scale. Data were analyzed using SPSS version 20 through descriptive statistics and Pearson correlation.
Findings: The overall level of death anxiety in patients was moderate. There was a significant relationship between death anxiety and variables such as age, sex, marital status, employment, and the presence of underlying disease (P≤0.05). However, no significant relationship was found with place of residence (urban/rural), education level, or duration of illness (P>0.05).
Conclusion: Death anxiety is prevalent among heart patients awaiting CABG. It is essential for healthcare providers, especially nurses in cardiac units, to recognize and address this concern. Understanding contributing factors can guide supportive interventions. Therefore, it is recommended to incorporate the topic of death anxiety into the training programs for caregivers of cardiac patients.
If you'd like a version under 200 or 150 words, I can adjust it further.
View Abstract
Methods: This descriptive-correlational study was conducted in 2024 at Shariati Hospital in Isfahan. A total of 100 CABG candidates admitted to the cardiac intensive care unit were selected via convenience sampling. After obtaining informed consent, participants were instructed on completing a questionnaire, which consisted of three parts: demographic data and Templer's Death Anxiety Scale. Data were analyzed using SPSS version 20 through descriptive statistics and Pearson correlation.
Findings: The overall level of death anxiety in patients was moderate. There was a significant relationship between death anxiety and variables such as age, sex, marital status, employment, and the presence of underlying disease (P≤0.05). However, no significant relationship was found with place of residence (urban/rural), education level, or duration of illness (P>0.05).
Conclusion: Death anxiety is prevalent among heart patients awaiting CABG. It is essential for healthcare providers, especially nurses in cardiac units, to recognize and address this concern. Understanding contributing factors can guide supportive interventions. Therefore, it is recommended to incorporate the topic of death anxiety into the training programs for caregivers of cardiac patients.
If you'd like a version under 200 or 150 words, I can adjust it further.
Systematic Review of Clinical Trials of Herbal Products on Menstrual Bleeding Severity
Fatemeh Hekmatzadeh, Fatemeh Goudarzi
Aim This study aimed to systematically review clinical trials of herbal products on the severity of menstrual bleeding.
Information & Methods In this review, all articles that used clinical trial methods in the field of "effectiveness of herbal compounds in the treatment of heavy menstrual bleeding" were searched without time limit until October 2024. Persian and English sources and search engines Pubmed, Cochrane, Web of Science, Scopus, Magiran, SID Iranmedex were reviewed. Keywords based on mesh that included menstrual bleeding, herbal medicine, complementary medicine, alternative care were used for the search. AND, OR operators were used in the search. These databases were searched without time limit until October 2024.
Findings Out of 28108 articles, 16 articles were reviewed. Most of the herbs reviewed reduced menstrual bleeding. The results of several studies on the effects of ginger, chamomile, and fennel on reducing menstrual bleeding were consistent.
Conclusion The medicinal products prepared in all studies were reported to be effective in reducing menstrual bleeding. Due to the insufficient number of articles on the herbs reviewed, further studies with different forms and doses are necessary to achieve reliable results and determine the effective dose and form of these herbs.
View Abstract
Information & Methods In this review, all articles that used clinical trial methods in the field of "effectiveness of herbal compounds in the treatment of heavy menstrual bleeding" were searched without time limit until October 2024. Persian and English sources and search engines Pubmed, Cochrane, Web of Science, Scopus, Magiran, SID Iranmedex were reviewed. Keywords based on mesh that included menstrual bleeding, herbal medicine, complementary medicine, alternative care were used for the search. AND, OR operators were used in the search. These databases were searched without time limit until October 2024.
Findings Out of 28108 articles, 16 articles were reviewed. Most of the herbs reviewed reduced menstrual bleeding. The results of several studies on the effects of ginger, chamomile, and fennel on reducing menstrual bleeding were consistent.
Conclusion The medicinal products prepared in all studies were reported to be effective in reducing menstrual bleeding. Due to the insufficient number of articles on the herbs reviewed, further studies with different forms and doses are necessary to achieve reliable results and determine the effective dose and form of these herbs.
Effect of patient Safety Culture on the Nurses's professional Behavior: A Field Trial Study
Mohammad Zoladl, MohammadSajjad Mousavi, Mohammadlatif Rastian, Fatemeh Tabatabaei, Mohsen Salari
Introduction & Objective: Patient safety is one of the fundamental pillars of healthcare and plays a crucial role in the quality of nursing services. Promoting a culture of safety can enhance nurses' professional behavior and help prevent medical errors. Therefore, this study was conducted to determine the effect of patient safety culture on professional behavior of the nurses.
Materials & Methods: In this randomized field trial, 84 eligible nurses from hospitals in Yasuj were randomly assigned to intervention and control groups using block randomization. Data on professional behavior of the nurses were collected both before the intervention and one month afterward. The collected data were analyzed using SPSS version 21, with a 95% confidence level. Chi-square, independent t-test, and paired t-test were used for statistical analysis.
Results: After the intervention, there was a statistically significant difference in the overall professional behavior scores between the intervention and control groups, with mean (SD) scores of 96.40 (12.70) and 52.00 (9.40), respectively (P < 0.0001).
Conclusion: Training in patient safety culture led to an improvement in professional behavior of the nurses.
View Abstract
Materials & Methods: In this randomized field trial, 84 eligible nurses from hospitals in Yasuj were randomly assigned to intervention and control groups using block randomization. Data on professional behavior of the nurses were collected both before the intervention and one month afterward. The collected data were analyzed using SPSS version 21, with a 95% confidence level. Chi-square, independent t-test, and paired t-test were used for statistical analysis.
Results: After the intervention, there was a statistically significant difference in the overall professional behavior scores between the intervention and control groups, with mean (SD) scores of 96.40 (12.70) and 52.00 (9.40), respectively (P < 0.0001).
Conclusion: Training in patient safety culture led to an improvement in professional behavior of the nurses.
The effect of sildenafil on fetal heart rate pattern during labor: a single-blind, randomized controlled trial
Zahra Asadikalameh, Fatemeh Golshahi, Mahboubeh Sharifi
Aims We aimed to evaluate the impact of sildenafil on the fetal heart rate pattern during delivery.
Materials & Methods The study was a single-blind randomized controlled trial carried out in the maternity unit of Imam Sajjad Hospital, Yasuj, in 2024. A total of two hundred patients were randomly assigned to two groups. In addition to standard practices during labor, the intervention group received oral sildenafil at a dose of 50 mg every 8 hours, not surpassing 150 mg, starting with the initial dose at the onset of the study. In the control group, standard routine care was implemented. The main outcome measure was fetal heart rate patterns. The secondary outcome measures included labor duration, meconium amniotic fluid, delivery method, postpartum hemorrhage, Apgar score, admission to the neonatal intensive care unit, and adverse effects.
Findings 96 cases in the Sildenafil group and 102 cases in the control group were included in the analysis. The reassuring fetal heart rate pattern was more common in the sildenafil group (80.2% compared to 56.9%). Among various non-reassuring fetal heart rate patterns, tachycardia and bradycardia were the most prevalent fetal heart rate patterns in the control group when compared to sildenafil. Cesarean sections were more frequent in the control group than in the sildenafil group. The neonatatl outcomes were similar in both groups. No side effects were reported.
Conclusion The impact of sildenafil on reducing nonreassuring fetal heart rate patterns revealed encouraging results. Further studies with larger sample sizes are needed for clearer conclusions.
View Abstract
Materials & Methods The study was a single-blind randomized controlled trial carried out in the maternity unit of Imam Sajjad Hospital, Yasuj, in 2024. A total of two hundred patients were randomly assigned to two groups. In addition to standard practices during labor, the intervention group received oral sildenafil at a dose of 50 mg every 8 hours, not surpassing 150 mg, starting with the initial dose at the onset of the study. In the control group, standard routine care was implemented. The main outcome measure was fetal heart rate patterns. The secondary outcome measures included labor duration, meconium amniotic fluid, delivery method, postpartum hemorrhage, Apgar score, admission to the neonatal intensive care unit, and adverse effects.
Findings 96 cases in the Sildenafil group and 102 cases in the control group were included in the analysis. The reassuring fetal heart rate pattern was more common in the sildenafil group (80.2% compared to 56.9%). Among various non-reassuring fetal heart rate patterns, tachycardia and bradycardia were the most prevalent fetal heart rate patterns in the control group when compared to sildenafil. Cesarean sections were more frequent in the control group than in the sildenafil group. The neonatatl outcomes were similar in both groups. No side effects were reported.
Conclusion The impact of sildenafil on reducing nonreassuring fetal heart rate patterns revealed encouraging results. Further studies with larger sample sizes are needed for clearer conclusions.
A Comparison of the Effects of Interferon Beta-1 (IFN-beta-1) and Dexamethasone on the Treatment of Hospitalized COVID-19 Patients
Mohammad amin Fazeli, Mohammad Malekzadeh, Habibeh Bayatmanesh, Parisa Neysarian, Nasir Arefkhaha, Moslem Sedaghattalab
Background: Despite the emergency need for treat the COVID-19 pandemic, there is no effective treatment to date. The present study aimed to compare the effects of interferon Beta-1 and dexamethasone on the treatment of hospitalized COVID-19 patients.
Methods: This phase 2, open-label, and randomized trial examined adult patients who admitted to hospitals of Yasuj, Iran from October 2021 to May 2022 due to COVID-19. Patients were randomly assigned into the intervention group1(88 patient), including Remdesivir, Interferon beta-1, and dexamethasone, and the intervention group2 (88 patient), including Remdesivir and dexamethasone in a ratio of 1:1. The mean arterial blood oxygen(O2) saturation, and length of hospitalization of both groups were compared.
Results: The two groups had no significant difference in terms of demographic characteristics, and disease related variables at the beginning of the study (P>0.05).
The mean and standard deviation of the O2 saturation at the time of discharge in group1 (90.14 ± 10.72) and group2 (92.54 ± 3.19) showed a significant difference (p<0.05). The mean and standard deviation of the length of hospitalization in the group1 (7.02 ± 2.56) and group2 (5.73 ± 2.04) were significantly different (p<0.01). There was a significant difference between the number of deaths in group 1 (7 people) and group 2 (0 people). (P<0.01).
Conclusions: The administration of remdesivir and dexamethasone compared to remdesivir, dexamethasone, and interferon decreased the length of hospitalization, mortality and improved O2 saturation.
View Abstract
Methods: This phase 2, open-label, and randomized trial examined adult patients who admitted to hospitals of Yasuj, Iran from October 2021 to May 2022 due to COVID-19. Patients were randomly assigned into the intervention group1(88 patient), including Remdesivir, Interferon beta-1, and dexamethasone, and the intervention group2 (88 patient), including Remdesivir and dexamethasone in a ratio of 1:1. The mean arterial blood oxygen(O2) saturation, and length of hospitalization of both groups were compared.
Results: The two groups had no significant difference in terms of demographic characteristics, and disease related variables at the beginning of the study (P>0.05).
The mean and standard deviation of the O2 saturation at the time of discharge in group1 (90.14 ± 10.72) and group2 (92.54 ± 3.19) showed a significant difference (p<0.05). The mean and standard deviation of the length of hospitalization in the group1 (7.02 ± 2.56) and group2 (5.73 ± 2.04) were significantly different (p<0.01). There was a significant difference between the number of deaths in group 1 (7 people) and group 2 (0 people). (P<0.01).
Conclusions: The administration of remdesivir and dexamethasone compared to remdesivir, dexamethasone, and interferon decreased the length of hospitalization, mortality and improved O2 saturation.
The Effectiveness of Narcotics Anonymous Group Therapy on Impulsivity and the Brain-Behavioral Systems in Individuals with Substance Use Disorders
Nazanin Rahmatian Dehkordi, Alireza Taghvaee, Manouchehr Sattari Naeini
Aims: Impulsivity and dysregulated neural circuits characterize substance use disorders, necessitating interventions like Narcotics Anonymous (NA) to enhance self-regulation and recovery outcomes. This study aimed to evaluate the impact of engagement in NA group therapy on the reduction of impulsivity and the modulation of the brain-behavioral systems among individuals diagnosed with substance use disorders (SUDs).
Materials & Methods: This study utilized a quasi-experimental pre-test-post-test control group design to assess the effectiveness of the intervention. The study population comprised individuals with SUDs who sought support from the Shahrekord Narcotics Anonymous Association in 2023. A sample of 40 participants was randomly allocated to either the experimental group, which received NA group therapy, or the control group, with 20 participants in each. The experimental group engaged in the NA Twelve Step Education Package, consisting of 12 weekly 90-minute sessions, whereas the control group received standard methadone maintenance treatment. Data on impulsivity and brain/behavioral systems were collected using validated questionnaires administered at both pre- and post-intervention time points. Analysis of covariance (ANCOVA) was employed using SPSS version 23 to analyze the data.
Findings: Engagement in NA group therapy resulted in a statistically significant reduction in impulsivity and a significant improvement in the functioning of the brain-behavioral systems within the experimental group when compared to the control group (P<0.01).
Conclusions: NA group therapy significantly reduces impulsivity and improves brain behavioral system functioning, enhancing self-regulation in individuals with SUDs, highlighting its efficacy as a community-based intervention for neurobehavioral outcomes and long-term recovery.
View Abstract
Materials & Methods: This study utilized a quasi-experimental pre-test-post-test control group design to assess the effectiveness of the intervention. The study population comprised individuals with SUDs who sought support from the Shahrekord Narcotics Anonymous Association in 2023. A sample of 40 participants was randomly allocated to either the experimental group, which received NA group therapy, or the control group, with 20 participants in each. The experimental group engaged in the NA Twelve Step Education Package, consisting of 12 weekly 90-minute sessions, whereas the control group received standard methadone maintenance treatment. Data on impulsivity and brain/behavioral systems were collected using validated questionnaires administered at both pre- and post-intervention time points. Analysis of covariance (ANCOVA) was employed using SPSS version 23 to analyze the data.
Findings: Engagement in NA group therapy resulted in a statistically significant reduction in impulsivity and a significant improvement in the functioning of the brain-behavioral systems within the experimental group when compared to the control group (P<0.01).
Conclusions: NA group therapy significantly reduces impulsivity and improves brain behavioral system functioning, enhancing self-regulation in individuals with SUDs, highlighting its efficacy as a community-based intervention for neurobehavioral outcomes and long-term recovery.
Effect of Faye Glenn Abdellah's Nursing Theory on Quality of Life in Cancer Patients: A Randomized Controlled Trial
Z. Mahmoudi, F. Rahimi Dolat Abad, L. Gholami, A.H. Bayat, M.S. Mirzaee, M. Alishapour
Aims: Cancer disrupts the quality of life of patients, as well as increases the care burden of the patients' families. The current study aimed to determine the effect of Glenn Abdellah's nursing theory on quality of life of patients with cancer.
Materials & Methods: In this randomized control trial, 60 patients with cancer were selected by purposive sampling method in Shahid Modarres Hospital, Saveh city in 2020.
Then the samples were divided into intervention and control groups using random allocation. Then the samples were divided into intervention (n=30) and control (n=30) groups using random allocation. The intervention related to ten steps in Faye Glenn Abdellah’s Nursing Theory was implemented for intervention group, but there was no intervention in the control group. Information was collected before, after the intervention, and one month after the intervention through World Health Organization Quality-of-Life Scale (WHOQOL-BREF). Data were analyzed by SPSS 22 software, using descriptive statistics methods and inferential analysis tests.
Findings: In the intervention group, the mean score of patients' quality of life increased significantly after intervention and one month after intervention (p<0.001). After intervention and the follow-up period, the quality of life in the intervention group was better than that of the control group (p<0.001).
Conclusion: The use of nursing care theories, such as Faye Glenn Abdellah's nursing theory, can improve the quality of life in cancer patients.
View Abstract
Materials & Methods: In this randomized control trial, 60 patients with cancer were selected by purposive sampling method in Shahid Modarres Hospital, Saveh city in 2020.
Then the samples were divided into intervention and control groups using random allocation. Then the samples were divided into intervention (n=30) and control (n=30) groups using random allocation. The intervention related to ten steps in Faye Glenn Abdellah’s Nursing Theory was implemented for intervention group, but there was no intervention in the control group. Information was collected before, after the intervention, and one month after the intervention through World Health Organization Quality-of-Life Scale (WHOQOL-BREF). Data were analyzed by SPSS 22 software, using descriptive statistics methods and inferential analysis tests.
Findings: In the intervention group, the mean score of patients' quality of life increased significantly after intervention and one month after intervention (p<0.001). After intervention and the follow-up period, the quality of life in the intervention group was better than that of the control group (p<0.001).
Conclusion: The use of nursing care theories, such as Faye Glenn Abdellah's nursing theory, can improve the quality of life in cancer patients.
Effect of Hypnosis on Pulmonary Function and Severity of the Disease in Asthmatic Patients: A Randomized Clinical Trial
Z. Mohebbi, Sh. Najafi Doulatabad, M. Malekzadeh, S.H. Nabavizadeh, H. Marioryad, E. Momeni , M. Niazi, M. Zoladl
Aim: Asthma is one of the common, chronic respiratory diseases which psychological factors play an important role in it and comorbidities of several psychological disorders such as anxiety, depression, and panic attacks are common in asthmatic patients. The aim of this study was to determine the effect of hypnosis on pulmonary function and severity of the disease in asthmatic patients.
Materials and Methods: This randomized clinical trial study, was carried out on 64 asthmatic patients, who referred to the clinic of Shahid Mofattah in Yasuj, Iran in 2010. The subjects were selected by purposeful sampling method, and randomly assigned into the tow group of the intervention (subjects were treated by solo hypnosis in a 90-minute session and conventional treatments) and control group (subjects were treated by conventional treatments, in addition, providing an explanation about requirement care point for improvement of asthma in 15 minutes) by use of balanced block randomization. In addition to completing demographic information at the beginning of the study, determination of pulmonary function and asthma severity were conducted respectively through measurement of FEV1 and NAEPP classification (EPR-3) at the starting point of the study and one month after the completion of the research intervention. Data were analyzed using SPSS 21 software, through independent sample t-test, paired sample t-test, Chi-square test, and marginal homogeneity test.
Findings: one month after completing the research intervention, the FEV1 in the intervention group increased than the control group and the severity of asthma in the intervention group decreased than the control group.
Conclusion: Hypnosis as an adjuvant treatment is effective in the improvement of pulmonary function and reducing the disease severity in asthmatic patients.
View Abstract
Materials and Methods: This randomized clinical trial study, was carried out on 64 asthmatic patients, who referred to the clinic of Shahid Mofattah in Yasuj, Iran in 2010. The subjects were selected by purposeful sampling method, and randomly assigned into the tow group of the intervention (subjects were treated by solo hypnosis in a 90-minute session and conventional treatments) and control group (subjects were treated by conventional treatments, in addition, providing an explanation about requirement care point for improvement of asthma in 15 minutes) by use of balanced block randomization. In addition to completing demographic information at the beginning of the study, determination of pulmonary function and asthma severity were conducted respectively through measurement of FEV1 and NAEPP classification (EPR-3) at the starting point of the study and one month after the completion of the research intervention. Data were analyzed using SPSS 21 software, through independent sample t-test, paired sample t-test, Chi-square test, and marginal homogeneity test.
Findings: one month after completing the research intervention, the FEV1 in the intervention group increased than the control group and the severity of asthma in the intervention group decreased than the control group.
Conclusion: Hypnosis as an adjuvant treatment is effective in the improvement of pulmonary function and reducing the disease severity in asthmatic patients.
Performance Indicators of Affiliated Hospitals to Yasuj University of Medical Sciences, Iran (2011-2018): Pabon Lasso Model
A. Mousavizadeh, L. Manzouri, A. Karimi Baseri
Aims: Hospital indicators are one of the most important criteria of hospital efficiency. The aim of this study was to determine the performance indicators of affiliated hospitals of Yasuj University of Medical Sciences in 2011-2018.
Instruments & Methods: This cross-sectional descriptive study was conducted on 5 hospitals, including Shahid Beheshti, Shahid Rajaei, and Emam-Sajjad Yasuj hospitals, and Shahid Rajaei Hospital in Gachsaran and Emam-Khomeini Hospital in Dehdasht affiliated to Yasuj University of Medical Sciences in 2011-2018. Bed Occupancy Rate (BOR), Bed Turnover (BTR) and Average Length of Stay (ALS) were collected through hospital information system and analyzed according to Pabon Lasso model and compared with the standard levels.
Findings: The mean BTR (98.76 times per year), ALS (2.12 days) and BOR (70.9%) in hospitals in 2011-2018 were favorable. ALS was 15.24 days in Shahid Rajaei hospital in Yasuj. Shahid Beheshti hospital was in zone 3 in all years. Emam-Sajjad hospital was in zone 3 in all years except 2014. Shahid Rajaei hospital of Yasuj was in zone 4 in 2011-2018. Emam-Khomeini hospital was in zone 1 in 2015-2016, zone 3 in 2011-2012, 2014, 2017-2018, and zone 4 in 2013. Shahid Rajaei hospital of Gachsaran was in zone 3 only in 2012, zone 1 in 2016-2019 and zone 2 in 2011 and 2013-2015.
Conclusion: The performance indicators of affiliated hospitals of Yasuj University of Medical Sciences are at the favorable and moderate level, and in total, in 2011-2018, most of the hospitals have been in zone 3, which indicates good performance.
View Abstract
Instruments & Methods: This cross-sectional descriptive study was conducted on 5 hospitals, including Shahid Beheshti, Shahid Rajaei, and Emam-Sajjad Yasuj hospitals, and Shahid Rajaei Hospital in Gachsaran and Emam-Khomeini Hospital in Dehdasht affiliated to Yasuj University of Medical Sciences in 2011-2018. Bed Occupancy Rate (BOR), Bed Turnover (BTR) and Average Length of Stay (ALS) were collected through hospital information system and analyzed according to Pabon Lasso model and compared with the standard levels.
Findings: The mean BTR (98.76 times per year), ALS (2.12 days) and BOR (70.9%) in hospitals in 2011-2018 were favorable. ALS was 15.24 days in Shahid Rajaei hospital in Yasuj. Shahid Beheshti hospital was in zone 3 in all years. Emam-Sajjad hospital was in zone 3 in all years except 2014. Shahid Rajaei hospital of Yasuj was in zone 4 in 2011-2018. Emam-Khomeini hospital was in zone 1 in 2015-2016, zone 3 in 2011-2012, 2014, 2017-2018, and zone 4 in 2013. Shahid Rajaei hospital of Gachsaran was in zone 3 only in 2012, zone 1 in 2016-2019 and zone 2 in 2011 and 2013-2015.
Conclusion: The performance indicators of affiliated hospitals of Yasuj University of Medical Sciences are at the favorable and moderate level, and in total, in 2011-2018, most of the hospitals have been in zone 3, which indicates good performance.
Psychometric Properties of the Iranian Version of Physical Disability Sexual and Body Esteem Questionnaire in Women with Polycystic Ovary Syndrome
Sh. Aramesh , H. Allan, F. Bazarganipour , Z. khashavi, M. Taheri, Sh. Salari
Aims: The objective of this study was to evaluate the psychometric properties of the Iranian version of the physical disability sexual and body esteem questionnaire (PDSBE) in women with polycystic ovary syndrome (PCOS).
Materials & Methods: The present cross sectional study was conducted on 100 women with PCOS referred to the infertility clinic in Hormozgan province, Iran. After translating the questionnaire and to determine the linguistic validity, a panel of experts evaluated the content validity index (CVI) and content validity ratio (CVR). Exploratory factor analysis (EFA) was done to assess the questionnaire structure. Discriminate and convergent validity were evaluated, using known group comparisons and correlating PDSBE with body image concern inventory (BICI).
Finding: CVI and CVR results were 0.9 and 0.95, respectively. The results of EFA showed a 2 factor structure (sexual esteem and sexual attraction perceived by others) responsible for 61.21% of variance. A Cronbach's alpha test of the questionnaire was satisfactory. The results of known group comparisons showed that PDSBE differentiates well between patients, who differ in terms of clinical characteristics. Moreover, the results of convergent validity were indicative of a desirable correlation between the scores of BICI questionnaire and the domains of sexual esteem (r=0.43, p<0.001) and attractiveness of PDSBE (r= 0.48; p<0.001).
Conclusion: The PDSBE is an understandable and readable questionnaire. Also, women with normal clinical features had higher level of sexual esteem and felt more attractive.
Materials & Methods: The present cross sectional study was conducted on 100 women with PCOS referred to the infertility clinic in Hormozgan province, Iran. After translating the questionnaire and to determine the linguistic validity, a panel of experts evaluated the content validity index (CVI) and content validity ratio (CVR). Exploratory factor analysis (EFA) was done to assess the questionnaire structure. Discriminate and convergent validity were evaluated, using known group comparisons and correlating PDSBE with body image concern inventory (BICI).
Finding: CVI and CVR results were 0.9 and 0.95, respectively. The results of EFA showed a 2 factor structure (sexual esteem and sexual attraction perceived by others) responsible for 61.21% of variance. A Cronbach's alpha test of the questionnaire was satisfactory. The results of known group comparisons showed that PDSBE differentiates well between patients, who differ in terms of clinical characteristics. Moreover, the results of convergent validity were indicative of a desirable correlation between the scores of BICI questionnaire and the domains of sexual esteem (r=0.43, p<0.001) and attractiveness of PDSBE (r= 0.48; p<0.001).
Conclusion: The PDSBE is an understandable and readable questionnaire. Also, women with normal clinical features had higher level of sexual esteem and felt more attractive.
Effect of Caffeine on Coughing in Children Aged 3-36 Months: A Randomized Clinical Trial
M. Tagrian Esfahani , K. Keshavarz, A. Keshtkari, H. Sadeghi Mansourkhani, M. Akbartabar Toori , M. Zoladl
Aims: Coughing is one of the most common clinical complaints in pediatric medicine. Since caffeine, as a central nervous system stimulant from methylxanthine, inhibits tumor necrosis factor-alpha (TNFα) and leukotriene synthesis and reduces inflammation and initiates the immune process, the aim of this study was to determine the effect of caffeine on coughing in children aged 3-36 months.
Materials and Methods: In this randomized clinical trial study in 2015, among children referred to the Shahid Mofateh Pediatric Clinic of Yasuj, 120 children aged 3-36 months with coughing due to bronchiolitis, lower respiratory viral disease, increased airway sensitivity, or moderate persistent asthma were selected by convenience sampling method. They were assigned in intervention (reciving salbutamol and caffeine) and control (reciving salbutamol alone) groups by quadratic block randomization. In addition to completing demographic information at the beginning of the study, data on daily and nocturnal cough at the beginning of the study, 48 hours, 1 week, and 2 weeks after starting the drug were recorded. The data were analyzed by SPSS 21 software, using Mann-Whitney test, Chi-square or Fisher's exact test, generalized estimating equation, Friedman, and Wilcoxon statistical tests.
Findings: Daily cough and nocturnal cough significantly decreased in the intervention group at 48 hours, 1 and 2 weeks after beginning the treatment (p<0.05).
Conclusion: Prescription of caffeine with salbutamol is effective in accelerating improvement of cough in children.
View Abstract
Materials and Methods: In this randomized clinical trial study in 2015, among children referred to the Shahid Mofateh Pediatric Clinic of Yasuj, 120 children aged 3-36 months with coughing due to bronchiolitis, lower respiratory viral disease, increased airway sensitivity, or moderate persistent asthma were selected by convenience sampling method. They were assigned in intervention (reciving salbutamol and caffeine) and control (reciving salbutamol alone) groups by quadratic block randomization. In addition to completing demographic information at the beginning of the study, data on daily and nocturnal cough at the beginning of the study, 48 hours, 1 week, and 2 weeks after starting the drug were recorded. The data were analyzed by SPSS 21 software, using Mann-Whitney test, Chi-square or Fisher's exact test, generalized estimating equation, Friedman, and Wilcoxon statistical tests.
Findings: Daily cough and nocturnal cough significantly decreased in the intervention group at 48 hours, 1 and 2 weeks after beginning the treatment (p<0.05).
Conclusion: Prescription of caffeine with salbutamol is effective in accelerating improvement of cough in children.
Comparison the Effect of Fennel on Maternal Serum Prolactin Level and Neonatal Weight Gain with Effect of Domperidon and Placebo
A. Keshtkari, A. Mehboudi, M.A. Ghatee, N. Bagheri
Aims: Breastfeeding is an economic and valuable method to protect infant health during the life and provides unique biological and emotional effect for mothers and infants. The aim of this study was to compare the effect of fennel on maternal serum prolactin level and neonatal weight gain to effect of domperidon and placebo on these variables.
Materials & Methods: In this single blind randomized clinical trial (RCT), 150 volunteer mothers who had delivery and their newborns in Imam Sajad Hospital of Yasuj University of Medical Science, Yasuj, Iran in 2018, were selected by convenience sampling method and randomly assigned into three equal groups: placebo, domperidone, and fennel groups. Participants used placebo, domperidone tablets and fennel seeds powder for 14 days. Serum prolactin levels of mothers were measured with ELISA method before and after interventions. The weight of newborns were measured using digital scales on birth day, 14th and 28th days of study. Data were analyzed by SPSS 21 software using Chi square test, paired t-test, and one-way ANOVA.
Findings: The mean serum prolactin level of the mothers before and after intervention in all three groups were not significantly different (p>0.05). The mean weight of neonates on the birth day, 14th day and 28th day in three groups did not show any significant difference (p>0.05).
Conclusion: Fennel and domperidone have no effect on the serum prolactin level of lactating mothers and weight gain of newborns.
Effect of Aspirin on Pre-eclampsia and Fetal Growth Restriction in Obese Pregnant Women: A Randomized Controlled Clinical Trial
R. Vanda, Sh. Aramesh, M. Sadeghian, M.A. Ghatee, P. Ghaffari
Aim(s): Obesity in pregnant women is a serious health problem that has many complications such as pre-eclampsia and fetal growth restriction (FGR). The aim of the present study was to evaluate the effect of aspirin on prevalence of pre-eclampsia and FGR in obese pregnant women.
Materials & Methods: This randomized controlled clinical trial was conducted on 187 pregnant women referring to birth center of Mofatteh Clinic, Yasuj University of Medical Sciences, Yasuj, Iran in 2017-2018.
The subjects were selected using purposive sampling method and randomly divided into two groups; intervention group (n=89) and control group (n=98). The intervention group received 80mg/day aspirin and the control group received placebo at 13-20 weeks of gestation until 34 weeks of pregnancy. Data were analyzed by SPSS 21 software using Chi square test.
Findings: The prevalence of pre-eclampsia (1.1 vs. 11.2) and FGR (3.4 vs. 21.4) were significantly lower in the intervention group compared to the control group (p<0.05).
Conclusion: Administration of 80mg/daily of aspirin from 13-20 weeks of gestation in obese pregnant women reduces the incidence of pre-eclampsia and FGR, which could support the positive role of aspirin in preventing pre-eclampsia and FGR.
View Abstract
Materials & Methods: This randomized controlled clinical trial was conducted on 187 pregnant women referring to birth center of Mofatteh Clinic, Yasuj University of Medical Sciences, Yasuj, Iran in 2017-2018.
The subjects were selected using purposive sampling method and randomly divided into two groups; intervention group (n=89) and control group (n=98). The intervention group received 80mg/day aspirin and the control group received placebo at 13-20 weeks of gestation until 34 weeks of pregnancy. Data were analyzed by SPSS 21 software using Chi square test.
Findings: The prevalence of pre-eclampsia (1.1 vs. 11.2) and FGR (3.4 vs. 21.4) were significantly lower in the intervention group compared to the control group (p<0.05).
Conclusion: Administration of 80mg/daily of aspirin from 13-20 weeks of gestation in obese pregnant women reduces the incidence of pre-eclampsia and FGR, which could support the positive role of aspirin in preventing pre-eclampsia and FGR.
Comparison of Deferoxamine, Deferiprone and Deferasirox Iron-Chelating Agents in Reducing Serum Ferritin Levels in Patients with Thalassemia Major
A. Arya, S. Jokar, P. Etemadfar, J.M. Malekzadeh, R. Jannesar, M. Rohani, T. Mohamadi, F. Kharaman, M. Yosefi, S. Hatamipour, A. Roozbehi
Aims: Patients with thalassemia major suffer from iron overload due to excessive cell lysis. Iron-chelating agents are used to preventing the effects of iron overload on the body. Deferoxamine, deferiprone, and deferasirox are the most common iron-chelating agents. The aim of this study was to compare deferoxamine, deferiprone, and deferasirox iron-chelating agents in reducing serum ferritin levels in patients with thalassemia major.
Instrument & Methods: This descriptive cross-sectional study was performed on 114 thalassemia major patients in the Cooley's ward of Shahid Beheshti Hospital, Yasuj, Iran, in 2018 who had been taking iron supplements for the past year. Census sampling was done. After recording patients’ information, such as age, sex, and type of iron used, the blood sample was taken from the patients to measure serum ferritin and the results were analyzed using SPSS 22 software and multivariate analysis of variance.
Findings: The mean serum ferritin level was 3438.70±2872.88 ng/ml. 14 patients were taking deferoxamine, 62 patients were using deferiprone, and 38 patients were consuming deferasirox. There was no significant difference between iron-chelating agents in reducing ferritin levels (p>0.05). Also, there was no significant difference between males and females in terms of decreased ferritin levels (p>0.05).
Conclusion: There is no difference between deferoxamine, deferiprone and deferasirox iron-chelating agents in reducing the ferritin levels of patients with thalassemia and all can be administrated considering the cost, availability, condition, and patient's desire.
View Abstract
Instrument & Methods: This descriptive cross-sectional study was performed on 114 thalassemia major patients in the Cooley's ward of Shahid Beheshti Hospital, Yasuj, Iran, in 2018 who had been taking iron supplements for the past year. Census sampling was done. After recording patients’ information, such as age, sex, and type of iron used, the blood sample was taken from the patients to measure serum ferritin and the results were analyzed using SPSS 22 software and multivariate analysis of variance.
Findings: The mean serum ferritin level was 3438.70±2872.88 ng/ml. 14 patients were taking deferoxamine, 62 patients were using deferiprone, and 38 patients were consuming deferasirox. There was no significant difference between iron-chelating agents in reducing ferritin levels (p>0.05). Also, there was no significant difference between males and females in terms of decreased ferritin levels (p>0.05).
Conclusion: There is no difference between deferoxamine, deferiprone and deferasirox iron-chelating agents in reducing the ferritin levels of patients with thalassemia and all can be administrated considering the cost, availability, condition, and patient's desire.
Association between IL-10 rs1800872 Polymorphism in the Promoter Region of Human IL-10 Gene and Susceptibility to Rheumatoid Arthritis in the Patients in Southwest of Iran
S. Hassanzadeh, F. Hedayati, E. Hosseini, J.M. Malekzadeh, E. Masnavi, A. Keshtkari
Aims: Interleukin-10 is an important immunoregulatory cytokine that has an inhibitory effect on the initiation and progression of inflammatory responses in different situations such as autoimmune diseases including rheumatoid arthritis. Polymorphism in IL-10 promoter region affects the expression of this gene. It therefore seems reasonable that these polymorphisms may contribute to rheumatoid arthritis susceptibility in special populations. the aim of this study was to investigate the association between IL-10 rs1800872 polymorphism in the promoter region of human IL-10 gene and susceptibility to rheumatoid arthritis in the patients in southwest of Iran.
Materials & Methods: The present study is a case-control study conducted among patients with and without rheumatoid arthritis referred to the Mofateh clinic in Yasuj, Iran. Both case (n=64) and control (n=65) groups were selected using purposive sampling and were matched in terms of age, gender and ethnicity. Peripheral blood samples were collected from subjects and rs1800872 genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism method. SPSS 26.0 software was used for statistical analysis of data
Findings: The association between the frequency of TT genotypes and the incidence of rheumatoid arthritis was significant (OR=6.45; 95% CI= 1.30-32.00; p=0.023). On the other hand, the distribution of the T allele showed a significant relationship with rheumatoid arthritis (OR= 2.23; 95% CI= 1.26–3.97; p=0.006).
Conclusion: TT genotype of rs1800872 polymorphism is associated with rheumatoid arthritis susceptibility in southwestern Iranian population and can be considered as a risk factor for rheumatism.
View Abstract
Materials & Methods: The present study is a case-control study conducted among patients with and without rheumatoid arthritis referred to the Mofateh clinic in Yasuj, Iran. Both case (n=64) and control (n=65) groups were selected using purposive sampling and were matched in terms of age, gender and ethnicity. Peripheral blood samples were collected from subjects and rs1800872 genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism method. SPSS 26.0 software was used for statistical analysis of data
Findings: The association between the frequency of TT genotypes and the incidence of rheumatoid arthritis was significant (OR=6.45; 95% CI= 1.30-32.00; p=0.023). On the other hand, the distribution of the T allele showed a significant relationship with rheumatoid arthritis (OR= 2.23; 95% CI= 1.26–3.97; p=0.006).
Conclusion: TT genotype of rs1800872 polymorphism is associated with rheumatoid arthritis susceptibility in southwestern Iranian population and can be considered as a risk factor for rheumatism.
A survey about psoriasis patients in Yasuj, Iran
Z. Saeedinezhad, N. Dabiri
Aims: Psoriasis is a common immune-related skin disorder that affects 2-3% of worldwide people. This study aimed to determine the disease characteristics of psoriasis patients.
Materials & Methods: In this descriptive cross-sectional study, using the convenience sampling method, 164 psoriatic patients who were referred to a dermatology clinic in Yasuj from 2013 to 2014 participated. Demographic information and medical parameters were collected by a dermatologist through observation and using a researcher-made checklist. SPSS software version 19 was used for the statistical analysis of data.
Findings: Participants were consisting of 106 males and 58 females. The mean age of females was 28.72±15.89, and for males was 29.83±23.19. Most of them had the mild disease (48.3%), and common plaque-type psoriasis (87.7%). Sites of skin involvement were 80.4% on extremities. Nail involvement was 31.7% and arthritis was detected in 3% of cases. There was a history of pruritus or burning sensation in 41.5% of cases. There was only a 17.1% positive family history.
Conclusion: According to the results of this study, the ratio of men with psoriasis to women was higher. Most of the skin lesions caused by this disease were observed in the extremities, head, face and trunk, respectively, and in this respect both gender were similar and few participants reported a positive family history in this regard.
View Abstract
Materials & Methods: In this descriptive cross-sectional study, using the convenience sampling method, 164 psoriatic patients who were referred to a dermatology clinic in Yasuj from 2013 to 2014 participated. Demographic information and medical parameters were collected by a dermatologist through observation and using a researcher-made checklist. SPSS software version 19 was used for the statistical analysis of data.
Findings: Participants were consisting of 106 males and 58 females. The mean age of females was 28.72±15.89, and for males was 29.83±23.19. Most of them had the mild disease (48.3%), and common plaque-type psoriasis (87.7%). Sites of skin involvement were 80.4% on extremities. Nail involvement was 31.7% and arthritis was detected in 3% of cases. There was a history of pruritus or burning sensation in 41.5% of cases. There was only a 17.1% positive family history.
Conclusion: According to the results of this study, the ratio of men with psoriasis to women was higher. Most of the skin lesions caused by this disease were observed in the extremities, head, face and trunk, respectively, and in this respect both gender were similar and few participants reported a positive family history in this regard.
Effect of Prayer-Based Movements on Pain and Endurance of Flexor Muscles in Patients with Non-specific Chronic Low Back Pain
A. Jokarborzabad, Z. Karimi, P. Yazdanpanah, N. Roustaei, S. Mohammadhossini
Aims: Chronic non-specific low back pain is the most common chronic lower back pain, and developing a therapeutic and rehabilitative plan to more rapidly mend patients with lower back pain has always been discussed. The present study aimed to determine the effect of prayer-based movements on pain and endurance of flexor muscles in patients with non-specific chronic low back pain.
Materials & Methods: This quasi-experimental study was conducted on all the patients with a chronic non-specific LBP referring to Shahid Mofatteh Clinic No. 1 in Yasuj, 2020. According to block random assignment, Sixty-six patients were divided into two groups of the intervention and control. In the intervention group, prayer-based exercises were performed three sessions a week for eight weeks. The control group was not instructed. The demographic questionnaire and Quebec back pain disability scale were used to measure pain, and the maintain the 60° angle test was used to collect data before intervention; the visual pain measurement scale was used immediately after the intervention, and the endurance test of spine flexor muscles performed at the angle of 60° was used a week after the intervention. The collected data were analyzed by SPSS 21 using descriptive statistics and statistical tests of Paired T, Mann-Whitney, Independent T, Wilcoxon, Chi-square, and Shapiro-Wilk.
Findings: There was no significant difference between the two groups in terms of pain severity and endurance of the flexor muscles at the starting point (p>0.05). The comparisons of the mean immediately and a week after the intervention were significant (p<0.05).
Conclusion: Prayer-based exercises effectively affect pain severity and endurance of flexor muscles in patients with non-chronic lower back pain.
View Abstract
Materials & Methods: This quasi-experimental study was conducted on all the patients with a chronic non-specific LBP referring to Shahid Mofatteh Clinic No. 1 in Yasuj, 2020. According to block random assignment, Sixty-six patients were divided into two groups of the intervention and control. In the intervention group, prayer-based exercises were performed three sessions a week for eight weeks. The control group was not instructed. The demographic questionnaire and Quebec back pain disability scale were used to measure pain, and the maintain the 60° angle test was used to collect data before intervention; the visual pain measurement scale was used immediately after the intervention, and the endurance test of spine flexor muscles performed at the angle of 60° was used a week after the intervention. The collected data were analyzed by SPSS 21 using descriptive statistics and statistical tests of Paired T, Mann-Whitney, Independent T, Wilcoxon, Chi-square, and Shapiro-Wilk.
Findings: There was no significant difference between the two groups in terms of pain severity and endurance of the flexor muscles at the starting point (p>0.05). The comparisons of the mean immediately and a week after the intervention were significant (p<0.05).
Conclusion: Prayer-based exercises effectively affect pain severity and endurance of flexor muscles in patients with non-chronic lower back pain.
Comparison the Effect of Omeprazole, Esomeprazole and Lansoprazole on Treatment of Gastroesophageal Reflux Disease in Infants
R. Abassi , F. Abassi , A. Mosavizadeh , H. Sadeghi , A. Keshtkari
Aims: Gastroesophageal reflux Disease (GERD) results impairment in the quality of life of the infants. Various studies have shown that proton pump inhibitors have a beneficial effect on the treatment of GERD. The aim of this study was to compare the effect of omeprazole, esomeprazole, and lansoprazole in the treatment of GERD in infants.
Materials & Method: This study is a randomized double blinded clinical trial that was conducted on 2-24-month-old infants with GERD referred to the Shahid Mofatteh clinic in Yasuj, Iran in 2016. 90 samples were selected by purposive sampling method and randomly assigned to three intervention groups including lansoprazole, omeprazole and esomeprazole (30 subjects per group). Infants in each group daily received 1mg/kg body weight of their prescription drugs. Before and after two and four weeks of treatment, the GERD-Q questionnaire was completed. Data were analyzed by SPSS 21 software using statistical tests.
Findings: There was no significant difference in the severity of GERD among the 3 groups before and 2 and 4 weeks after the intervention. Although, esomeprazole had a greater and faster effect on recovery. The symptoms of GERD in esomeprazole group were similar to the other two groups, but this difference was not significant. However, each of the three interventions alone improved GERD.
Conclusion: All three drugs, lansoprazole, omeprazole, and esomeprazole, are effective on GERD recovery. In comparison, although there is no significant difference among these 3 drugs, However esomeprazole appears to have a better clinical effect.
Materials & Method: This study is a randomized double blinded clinical trial that was conducted on 2-24-month-old infants with GERD referred to the Shahid Mofatteh clinic in Yasuj, Iran in 2016. 90 samples were selected by purposive sampling method and randomly assigned to three intervention groups including lansoprazole, omeprazole and esomeprazole (30 subjects per group). Infants in each group daily received 1mg/kg body weight of their prescription drugs. Before and after two and four weeks of treatment, the GERD-Q questionnaire was completed. Data were analyzed by SPSS 21 software using statistical tests.
Findings: There was no significant difference in the severity of GERD among the 3 groups before and 2 and 4 weeks after the intervention. Although, esomeprazole had a greater and faster effect on recovery. The symptoms of GERD in esomeprazole group were similar to the other two groups, but this difference was not significant. However, each of the three interventions alone improved GERD.
Conclusion: All three drugs, lansoprazole, omeprazole, and esomeprazole, are effective on GERD recovery. In comparison, although there is no significant difference among these 3 drugs, However esomeprazole appears to have a better clinical effect.
Comparison of the Effect of Two Doses of Vitamin D (Vit D-Ca and Vit D-Ca+Vit D) from the 16th Week on Preterm Labor in Pregnant Women
N.S. Mosallanejad, A.V. Taghavi, M. Saadat, M. Rajaii, F. Bazarganipour
Aims Preterm labor (delivery earlier than 37 weeks) is one of the most common problems
with midwifery. Recently, vitamin D deficiencies have been reported with adverse maternal
outcomes such as pregnancy toxicity, intrauterine growth limitation, and preterm labor. The
aim of this study was to compare the effect of 2 doses of vitamin D (Vit D-Ca and Vit D-Ca+Vit
D) from the 16th week on preterm labor in pregnant women.
Materials & Methods The present single-blind randomized clinical trial was conducted
on 202 pregnant women referred to 5 obstetric and gynecological clinics in Bandar Abbas,
Hormozgan province, Iran during January 2016 to March 2017. The subjects were selected
by randomization sampling method and were randomly assigned into group A (n=150) and
group B (n=152). Group A received Vit D-Ca supplements, containing 400 IU/day, and group
B received Vit D-Ca supplement plus Vit D (with D3 brand), containing 1000 IU/day from
the 16th week of pregnancy until delivery. The subjects were examined from the 16th week
of pregnancy until delivery. The data were analyzed by SPSS 21 software, using independent
t-test, Mann-Whitney U test and Chi-square test.
Findings The incidence of preterm labor in the group receiving Vit D-Ca+Vit D (group B) was
24 (16.0%) and in the group receiving Vit D-Ca alone was 25 (16.7%). There was a significant
difference between the two groups in terms of preterm labor (p=0.01).
Conclusion Vit D-Ca plus Vit D intake reduces preterm labor in pregnant women more than
Vit D-Ca alone intake.
View Abstract
with midwifery. Recently, vitamin D deficiencies have been reported with adverse maternal
outcomes such as pregnancy toxicity, intrauterine growth limitation, and preterm labor. The
aim of this study was to compare the effect of 2 doses of vitamin D (Vit D-Ca and Vit D-Ca+Vit
D) from the 16th week on preterm labor in pregnant women.
Materials & Methods The present single-blind randomized clinical trial was conducted
on 202 pregnant women referred to 5 obstetric and gynecological clinics in Bandar Abbas,
Hormozgan province, Iran during January 2016 to March 2017. The subjects were selected
by randomization sampling method and were randomly assigned into group A (n=150) and
group B (n=152). Group A received Vit D-Ca supplements, containing 400 IU/day, and group
B received Vit D-Ca supplement plus Vit D (with D3 brand), containing 1000 IU/day from
the 16th week of pregnancy until delivery. The subjects were examined from the 16th week
of pregnancy until delivery. The data were analyzed by SPSS 21 software, using independent
t-test, Mann-Whitney U test and Chi-square test.
Findings The incidence of preterm labor in the group receiving Vit D-Ca+Vit D (group B) was
24 (16.0%) and in the group receiving Vit D-Ca alone was 25 (16.7%). There was a significant
difference between the two groups in terms of preterm labor (p=0.01).
Conclusion Vit D-Ca plus Vit D intake reduces preterm labor in pregnant women more than
Vit D-Ca alone intake.
Efficacy of Pregabalin on Reducing Pain in Patients with Lumbosacral Radiculopathy
H. Mohammadi, M. Afkari, N. Salehi, A. Roozbehi
Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.
Materials & Methods: In this clinical trial, 90 patients with lumbosacral radiculopathy referring to the clinic of Shahid Mofatteh, Yasuj, Iran in 2018, were selected using purposeful convenience sampling and divided into intervention (N=45) and control (N=45) groups. The pain severity was assessed by a standard visual analog scale (VAS). In the intervention group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin, and in the control group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin placebo were prescribed. After 8 weeks, the severity of the pain was again assessed and compared.
Findings: At the beginning of the study, the mean pain severity in the intervention and control group did not differ significantly (p>0.05). After the intervention, the mean pain severity between the two groups did not show a significant difference (p>0.05). The severity of the pain did not differ significantly between the two groups of intervention and control according to age, disease history, location of pain, and body weight (p>0.05).
Conclusion: The efficacy of pregabalin and NSAID in comparison with NSAID use in patients with lumbosacral radiculopathy is not different in reducing pain severity.Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.
View Abstract
Materials & Methods: In this clinical trial, 90 patients with lumbosacral radiculopathy referring to the clinic of Shahid Mofatteh, Yasuj, Iran in 2018, were selected using purposeful convenience sampling and divided into intervention (N=45) and control (N=45) groups. The pain severity was assessed by a standard visual analog scale (VAS). In the intervention group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin, and in the control group, 100 mg celecoxib every 12 hours, plus 75 mg per day pregabalin placebo were prescribed. After 8 weeks, the severity of the pain was again assessed and compared.
Findings: At the beginning of the study, the mean pain severity in the intervention and control group did not differ significantly (p>0.05). After the intervention, the mean pain severity between the two groups did not show a significant difference (p>0.05). The severity of the pain did not differ significantly between the two groups of intervention and control according to age, disease history, location of pain, and body weight (p>0.05).
Conclusion: The efficacy of pregabalin and NSAID in comparison with NSAID use in patients with lumbosacral radiculopathy is not different in reducing pain severity.Aims: Pregabalin is one of the anti-seizure and analgesic drugs, which is widely used in the treatment of neuropathic pain and chronic radiculopathy in the form of monotherapy. The aim of this study was to evaluate the effectiveness of pregabalin drug therapy with common treatment (an NSAID) on reducing pain in patients with lumbosacral radiculopathy.
Comparative Evaluation of the Clinical and Paraclinical Diagnosis in Patients with Acute Appendicitis
A. Azizi, F. Arefpoor, S. Jokar, R. Hoseinpoor
Aims: Acute appendicitis is the most common emergency surgery; thus, its diagnosis requires high accuracy. This study aimed to determine the agreement between clinical and paraclinical diagnoses in patients with acute appendicitis.
Instrument & Methods: This descriptive study was performed on patients referred to Shahid Beheshti Hospital in Yasouj with suspicion of acute appendicitis in 2018. After considering the inclusion criteria, the files of 200 patients were included in the study by purposive sampling. Age, sex, main problem, symptoms, clinical signs, white blood cell count, and ultrasonography and pathology report were extracted from the patients' files, and the Modified Alvarado Score was calculated based on their information.
Findings: The mean age of the patients was 24.3±13.2 years, and the most common symptoms were anorexia and abdominal tenderness. The Modified Alvarado Score was 4-6 in 126 (63%) and 7 or higher (37%) in 74 patients. In addition, 182 patients (91%) had a positive pathology for appendicitis. There was a statistically significant relationship (p=0.03) between Modified Alvarado Score and pathology; however, there was no statistically significant relationship (p=0.43) between Modified Alvarado Score and ultrasonography. There was a significant relationship (p=0.0001) between pathology and ultrasonography. The ultrasonography sensitivity was 37.1%, specificity was 87.2%, positive predictive value was 96.8%, and negative predictive value was 11.7%.
Conclusion: There is an agreement between the Modified Alvarado Score and ultrasonography in diagnosing acute appendicitis with the pathology as the gold standard in the diagnosis of appendicitis; however, there is no agreement between the Modified Alvarado Score and ultrasonography.
View Abstract
Instrument & Methods: This descriptive study was performed on patients referred to Shahid Beheshti Hospital in Yasouj with suspicion of acute appendicitis in 2018. After considering the inclusion criteria, the files of 200 patients were included in the study by purposive sampling. Age, sex, main problem, symptoms, clinical signs, white blood cell count, and ultrasonography and pathology report were extracted from the patients' files, and the Modified Alvarado Score was calculated based on their information.
Findings: The mean age of the patients was 24.3±13.2 years, and the most common symptoms were anorexia and abdominal tenderness. The Modified Alvarado Score was 4-6 in 126 (63%) and 7 or higher (37%) in 74 patients. In addition, 182 patients (91%) had a positive pathology for appendicitis. There was a statistically significant relationship (p=0.03) between Modified Alvarado Score and pathology; however, there was no statistically significant relationship (p=0.43) between Modified Alvarado Score and ultrasonography. There was a significant relationship (p=0.0001) between pathology and ultrasonography. The ultrasonography sensitivity was 37.1%, specificity was 87.2%, positive predictive value was 96.8%, and negative predictive value was 11.7%.
Conclusion: There is an agreement between the Modified Alvarado Score and ultrasonography in diagnosing acute appendicitis with the pathology as the gold standard in the diagnosis of appendicitis; however, there is no agreement between the Modified Alvarado Score and ultrasonography.
Effect of Oral Extract of Centella asiatica on Burn Pain and Wound Healing; A Randomized Controlled Trial
R. Kazemi Dermenaki Farahani , K. Rahzani, D. Hekmat Pu, A. Rostami
Aims: Burns and wounds caused by it are a global injury. Finding natural ingredients to accelerate wound healing in patients with fewer side effects could be valuable. This study aimed to determine the effect of oral Centella asiatica extract on the healing of pain and wound of burn in patients.
Materials & Methods: This study is a clinical trial in which 76 patients hospitalized in the burn department were randomly divided into two intervention (n=38) and control (n=38) groups. The intervention group, in addition to the usual antibiotic treatments, received capsules containing 200mg of Centella asiatica twice daily, and the control group received capsules containing 200mg of starch twice daily. Data collection tools were Bates-Jensen Wound Assessment tool and Visual Analog Scale. Patients' pain and wound healing status were examined at different time of the study.
Findings: The mean burn pain score showed a significant improvement in the intervention group compared to the control group (p<0.001). The average wound healing score did not show significant improvement in the intervention group compared to the control group (p=0.561). However, size (p=0.023), the degree of destruction of the underlying tissues (p=0.032), the amount of necrotic tissue (p=0.015), and the amount of granulation tissue (p=0.001) improved significantly in the intervention group. In addition, the peripheral tissue edema in the control group decrease significantly compared to the intervention group (p=0.008).
Conclusion: Oral extract of Centella asiatica reduces pain in burn patients. However, it does not affect wound healing, although it improves some wound healing indicators.
View Abstract
Materials & Methods: This study is a clinical trial in which 76 patients hospitalized in the burn department were randomly divided into two intervention (n=38) and control (n=38) groups. The intervention group, in addition to the usual antibiotic treatments, received capsules containing 200mg of Centella asiatica twice daily, and the control group received capsules containing 200mg of starch twice daily. Data collection tools were Bates-Jensen Wound Assessment tool and Visual Analog Scale. Patients' pain and wound healing status were examined at different time of the study.
Findings: The mean burn pain score showed a significant improvement in the intervention group compared to the control group (p<0.001). The average wound healing score did not show significant improvement in the intervention group compared to the control group (p=0.561). However, size (p=0.023), the degree of destruction of the underlying tissues (p=0.032), the amount of necrotic tissue (p=0.015), and the amount of granulation tissue (p=0.001) improved significantly in the intervention group. In addition, the peripheral tissue edema in the control group decrease significantly compared to the intervention group (p=0.008).
Conclusion: Oral extract of Centella asiatica reduces pain in burn patients. However, it does not affect wound healing, although it improves some wound healing indicators.
Fibroepithelial Stromal Polyp as Low Back Lesion in 88-year-old Man: a Case Report
z. Daneshyar, M. Shokripour
Introduction: Fibroepithelial stromal polyp (FESP) of the female lower genital tract is a rare benign lesion characterized by polypoid proliferation of stroma, covered by a benign squamous epithelium in the vulvovaginal region. These hormone-sensitive lesions usually occur in young to middle-aged women. The lesions are typically no larger than 5 cm in diameter and are found randomly during routine gynecologic examinations.
Patient Information: The case of this study was an 88-year-old man with a solitary polypoid lesion measuring 3×2×2 in the low back area showing the histological appearances of those described in the vulvovaginal region.
It was a well-circumscribed gray-brown lesion covered by wrinkled skin. Histopathological examination revealed edematous hypocellular lesion at low magnification with hyperplastic squamous epithelium coating with reactive epithelial change. At high magnification, the lesion consisted of bland-appearing spindle and stellate-shaped cells in an edematous and fibrous stroma with a large number of variably-sized blood vessels. Immunohistochemistry showed the lesional cells to be focally immunoreactive for EMA and negative for CD34, SMA in stromal cells.
Conclusion: FESPs is an uncommon benign lesion that can occur in men and areas other than the genitals with independence from female sex hormones. Although this is a benign finding, reporting it will increase the knowledge about this rare tumor.
View Abstract
Patient Information: The case of this study was an 88-year-old man with a solitary polypoid lesion measuring 3×2×2 in the low back area showing the histological appearances of those described in the vulvovaginal region.
It was a well-circumscribed gray-brown lesion covered by wrinkled skin. Histopathological examination revealed edematous hypocellular lesion at low magnification with hyperplastic squamous epithelium coating with reactive epithelial change. At high magnification, the lesion consisted of bland-appearing spindle and stellate-shaped cells in an edematous and fibrous stroma with a large number of variably-sized blood vessels. Immunohistochemistry showed the lesional cells to be focally immunoreactive for EMA and negative for CD34, SMA in stromal cells.
Conclusion: FESPs is an uncommon benign lesion that can occur in men and areas other than the genitals with independence from female sex hormones. Although this is a benign finding, reporting it will increase the knowledge about this rare tumor.
Comparison of the Effect of Teach-Back Method and Video Clip Training on the Sense of Coherence of Mothers with Children Suffering from Asthma
A. Poursamad, Z. Karimi, M.S. Mousavi
Aims: Mothers whose children suffer from chronic diseases experience high levels of stress. Promoting the sense of coherence can be a way to reduce the stress. The aim of this study was to compare the effect of teach-back method and video clip teaching on the sense of coherence of mothers with children suffering from asthma.
Materials & Methods: In this randomized controlled trial, 75 eligible mothers with children suffering from asthma in Yasuj in 2020 were selected by convenience sampling method and randomly assigned into three groups: video clip group, teach-back method group and control group. In video clip group, training was performed through a 15-minute clip in two sessions. In teach-back method group 8 training sessions were held. Data were collected using the Antonovsky's Sense of Coherence scale-13 at baseline and one month after the intervention. Data were analyzed using SPSS 21 by descriptive and inferential statistics.
Findings: Before the intervention, there was no significant difference in the mean score of sense of coherence and its subscale in the three groups (p>0.05). One month after the intervention, there was a significant difference in the mean score of sense of coherence and its subscales between the two intervention groups with the control group (p=0.001). Also, a significant difference was observed between the two intervention groups in the mean scores of the sense of coherence and comprehensibility (p<0.05).
Conclusion: Both video clip and teach-back methods improves mothers' sense of coherence, but teach-back method is more effective than video clip teaching.
View Abstract
Materials & Methods: In this randomized controlled trial, 75 eligible mothers with children suffering from asthma in Yasuj in 2020 were selected by convenience sampling method and randomly assigned into three groups: video clip group, teach-back method group and control group. In video clip group, training was performed through a 15-minute clip in two sessions. In teach-back method group 8 training sessions were held. Data were collected using the Antonovsky's Sense of Coherence scale-13 at baseline and one month after the intervention. Data were analyzed using SPSS 21 by descriptive and inferential statistics.
Findings: Before the intervention, there was no significant difference in the mean score of sense of coherence and its subscale in the three groups (p>0.05). One month after the intervention, there was a significant difference in the mean score of sense of coherence and its subscales between the two intervention groups with the control group (p=0.001). Also, a significant difference was observed between the two intervention groups in the mean scores of the sense of coherence and comprehensibility (p<0.05).
Conclusion: Both video clip and teach-back methods improves mothers' sense of coherence, but teach-back method is more effective than video clip teaching.
Effect of P6 Point Acupressure on Anxiety Caused by Venipuncture in Patients with Thalassemia: A Clinical Trial Study
S. Avini, M. Hosseini, M. Behnammoghadam, M. Zoladl
Aims: Anxiety caused by repeated venipuncture is common in patients with thalassemia in the thalassemia ward. Acupressure is one of the methods used to reduce patients' anxiety. This study aimed to determine the effect of the P6 point acupressure on anxiety caused by venipuncture in thalassemia patients.
Materials & Methods: This randomized controlled clinical trial was conducted on 80 patients with thalassemia at Shahid Beheshti Hospital in Yasuj city in 2019, who were divided into two intervention and control groups by blocked random allocation. Acupressure intervention was performed at P6 point on the inner side of the arm and in the cavity between the bones of the forearm, above the crease of the wrist. The Spielberger State-Trait Anxiety Inventory was used to collect information. Data were analyzed using descriptive and inferential statistics (independent t-test, paired t-test, and chi-square test) through SPSS 21 software.
Findings: There was no significant difference in the state and trait anxiety between the intervention and control groups at the beginning of the study (p>0.05). However, a significant difference was observed in the state anxiety between the intervention and control groups after the intervention (p<0.05), but there was no significant difference in the trait anxiety score between the two groups (p>0.05).
Conclusion: Acupressure reduces trait anxiety caused by venipuncture in thalassemia patients hospitalized to the thalassemia ward, while it does not affect their trait anxiety.
View Abstract
Materials & Methods: This randomized controlled clinical trial was conducted on 80 patients with thalassemia at Shahid Beheshti Hospital in Yasuj city in 2019, who were divided into two intervention and control groups by blocked random allocation. Acupressure intervention was performed at P6 point on the inner side of the arm and in the cavity between the bones of the forearm, above the crease of the wrist. The Spielberger State-Trait Anxiety Inventory was used to collect information. Data were analyzed using descriptive and inferential statistics (independent t-test, paired t-test, and chi-square test) through SPSS 21 software.
Findings: There was no significant difference in the state and trait anxiety between the intervention and control groups at the beginning of the study (p>0.05). However, a significant difference was observed in the state anxiety between the intervention and control groups after the intervention (p<0.05), but there was no significant difference in the trait anxiety score between the two groups (p>0.05).
Conclusion: Acupressure reduces trait anxiety caused by venipuncture in thalassemia patients hospitalized to the thalassemia ward, while it does not affect their trait anxiety.
Effect of Increasing the Speed of Pumped Blood Volume Delivered to the Dialyzer on the Sleep Quality of Patients Undergoing Hemodialysis
S. Zabolypour, A. Afrasiabifar, S. Mohammadi, M. Farzannia
Aims: Sleep is one of the basic physiological needs of human beings, and sleep quality is an effective criterion on the quality of life of hemodialysis patients. Therefore, paying attention to sleep and its improvement should be a priority in nursing care. This study aimed to determine the effect of increasing the pumped blood volume delivered to dialyzer on sleep quality in hemodialysis patients.
Materials & Methods: This semi-experimental study is a clinical trial carried out on 50 hemodialysis patients referred to the hospitals affiliated with Tehran University of Medical Sciences in 2011. Convenience sampling selected samples and randomly divided them into control and intervention groups through permuted block randomization. Data were collected by Pittsburgh Sleep Quality Index in the three stages before intervention and 2 and 4 weeks after intervention. The blood volume delivered to the dialyzer increased by 25ml in the first two weeks and 50ml in the second two weeks compared to before the intervention. Data were analyzed by SPSS 21 software using repeated measures ANOVA and Kruskal-Wallis test.
Findings: The mean score of sleep quality in the intervention group before the intervention and two and four weeks after the intervention were 10.2±2.6, 8.8±3.4 and 6.9±2.9, respectively and in the control group were 11.4±2.8, 12.5±3.3, and 12.6±3.4, respectively. There was no significant difference in the total score of sleep quality and some of its dimensions between the intervention and control groups (p<0.05).
Conclusion: Increasing blood volume delivered to the dialyzer has improved hemodialysis patients' sleep quality, and this improvement seems to be clinically significant.
View Abstract
Materials & Methods: This semi-experimental study is a clinical trial carried out on 50 hemodialysis patients referred to the hospitals affiliated with Tehran University of Medical Sciences in 2011. Convenience sampling selected samples and randomly divided them into control and intervention groups through permuted block randomization. Data were collected by Pittsburgh Sleep Quality Index in the three stages before intervention and 2 and 4 weeks after intervention. The blood volume delivered to the dialyzer increased by 25ml in the first two weeks and 50ml in the second two weeks compared to before the intervention. Data were analyzed by SPSS 21 software using repeated measures ANOVA and Kruskal-Wallis test.
Findings: The mean score of sleep quality in the intervention group before the intervention and two and four weeks after the intervention were 10.2±2.6, 8.8±3.4 and 6.9±2.9, respectively and in the control group were 11.4±2.8, 12.5±3.3, and 12.6±3.4, respectively. There was no significant difference in the total score of sleep quality and some of its dimensions between the intervention and control groups (p<0.05).
Conclusion: Increasing blood volume delivered to the dialyzer has improved hemodialysis patients' sleep quality, and this improvement seems to be clinically significant.
